Species Summary

  Experimental Data
 Saccharomyces cerevisiae

Compound Dosage Unit CG Lifespan(AVG/MED days) TG Lifespan(AVG/MED days) Lifespan Change(AVG/MED%) CG Lifespan(MAX days) TG Lifespan(MAX days) Lifespan Change(MAX%) Significant Strain Gender PubMed Active Label
neohesperidin 0.1 umol/L 0 S BY4742 31766122 Active
hesperetin 0.1 umol/L NS BY4742 31766122 Inactive
hesperidin 0.1 umol/L NS BY4742 31766122 Inactive
Inokosterone 3 umol/L 6.4 8.5 0.33 S K6001 35204097 Active
Inokosterone 0.1 umol/L 6.4 7.7 0.2 NS K6001 35204097 Inactive
Inokosterone 10 umol/L 6.4 7.7 0.2 NS K6001 35204097 Inactive
Inokosterone 0.3 umol/L 6.4 8 0.25 S K6001 35204097 Active
Inokosterone 1 umol/L 6.4 10.1 0.58 S K6001 35204097 Active
naringin 100 umol/L NS BY4742 31766122 Inactive
quercetin 200 umol/L 72.84 S BY4741 32394448 Active
quercetin 300 umol/L 79.72 S BY4741 32394448 Active
resveratrol 10 umol/L 6.4 8.6 0.34 S K6001 35204097 Active
hesperidin 10 umol/L 0 S K6001 22484922 Active
hesperidin 5 umol/L 0 S K6001 22484922 Active
Alstonia angustiloba leaf extract 100 ug/mL 0 S 1783 34685698 Active
Calotropis gigantea leaf extract 100 ug/mL 0 S 1783 34685698 Active
Manihot esculenta leaf extract 100 ug/mL 0 S 1783 34685698 Active
Tabernaemontana divaricata leaf extract 100 ug/mL 0 S 1783 34685698 Active
Thevetia peruviana leaf extract 100 ug/mL 0 S 1783 34685698 Active
Wodyetia bifurcata leaf extract 100 ug/mL 0 S 1783 34685698 Active
Ziziphus mauritiana leaf extract 100 ug/mL 0 S 1783 34685698 Active
Astaxanthin 30 umol/L S 30312390
caffeine 0.4 mM Unclear 18513215
(-)-Rapamycin 0.55 nM Unclear 18513215
resveratrol 100 mg/mL NS W303R 15684413 Inactive
resveratrol 100 mg/mL NS PSY316 15684413 Inactive
resveratrol 100 mg/mL NS BY4741 15684413 Inactive
spermidine 1 mM 20 S 19801973
4,4'-Dimethoxychalcone 50 umol/L 4.5 6 0.33 S 30842997 Active
Acetyl-L-carnitine 1 mM 13 23 62.4 Unclear CML3911A 20550520
Amarogentin 1 umol/L 7.8 9.8 0.26 S K6001 32831994 Active
Amarogentin 20 umol/L 7.8 8.1 0.04 NS K6001 32831994 Inactive
Amarogentin 3 umol/L 7.8 10.6 0.36 S K6001 32831994 Active
Amarogentin 10 umol/L 7.8 9.8 0.26 S K6001 32831994 Active
butein 10 umol/L 31 S PSY316AT 12939617 Active
Charantagenin E 1 umol/L 7.7 9.68 0.26 S K6001 29765490 Active
Charantagenin E 3 umol/L 7.7 9.75 0.27 S K6001 29765490 Active
charantoside II 3 umol/L 7.7 9.73 0.26 S K6001 29765490 Active
charantoside II 1 umol/L 7.7 9.63 0.25 S K6001 29765490 Active
charantoside IV 3 umol/L 7.7 9 0.17 S K6001 29765490 Active
charantoside IV 1 umol/L 7.7 9.03 0.17 S K6001 29765490 Active
CHEMBL400981 3 umol/L 7.7 10.1 0.31 S K6001 29765490 Active
CHEMBL400981 1 umol/L 7.7 9.68 0.26 S K6001 29765490 Active
CHLOROGENIC ACID 25 umol/L 5.84 8.15 0.4 S DBY746 32481725 Active
CHLOROGENIC ACID 10 umol/L 5.84 7.6 0.3 S DBY746 32481725 Active
CHLOROGENIC ACID 5 umol/L 5.84 6.4 0.1 NS DBY746 32481725 Inactive
Cucurbitacin B 0.3 umol/L 6.95 8.95 0.29 S K6001 31281576 Active
Cucurbitacin B 1 umol/L 7.05 9.65 0.37 S K6001 31281576 Active
Cucurbitacin B 0.4 umol/L 6.95 8.9 0.28 S K6001 31281576 Active
Cucurbitacin B 1 umol/L 6.95 9.6 0.38 S K6001 31281576 Active
2-Amino-2-Deoxy-D-Glucopyranose 0.5 mg/mL 0 NS W303R 11805047 Inactive
glycerol 1 M 49.8 S PSY316 12391171 Active
xylitol 1 M 36.8 S PSY316 12391171 Active
Ehretiquinone 3 umol/L 7.42 10.33 0.39 S K6001 33510837 Active
Ehretiquinone 10 umol/L 7.42 10.58 0.43 S K6001 33510837 Active
Ehretiquinone 0.1 umol/L 7.42 7.3 -0.02 NS K6001 33510837 Inactive
Ehretiquinone 30 umol/L 7.42 7.78 0.05 NS K6001 33510837 Inactive
Ehretiquinone 1 umol/L 7.42 9.63 0.3 S K6001 33510837 Active
Fisetin 10 umol/L 55 S PSY318AT 12939617 Active
Fisetin 10 umol/L 55 S 31201898 Active
Gentiopicroside 3 umol/L 8.05 10.25 0.27 S K6001 32832008 Active
Gentiopicroside 10 umol/L 8.05 10.48 0.3 S K6001 32832008 Active
Gentiopicroside 0.3 umol/L 8.05 8.08 0 NS K6001 32832008 Inactive
Gentiopicroside 30 umol/L 8.05 9.73 0.21 NS K6001 32832008 Inactive
Gentiopicroside 1 umol/L 8.05 11.35 0.41 S K6001 32832008 Active
D-Glc 20 % 63.1 S PSY316 12391171 Active
D-Glc 10 % 19.8 S PSY316 12391171 Active
Glyceollin 12.5 nM 40 S 24399048 Active
Goyaglycoside b 3 umol/L 7.7 10.25 0.33 S K6001 29765490 Active
Goyaglycoside b 1 umol/L 7.7 11.08 0.44 S K6001 29765490 Active
Goyaglycoside D 3 umol/L 7.7 10.08 0.31 S K6001 29765490 Active
Goyaglycoside D 1 umol/L 7.7 9.55 0.24 S K6001 29765490 Active
guanine 20 umol/L 23.39 22.7 -0.03 NS BY4741 32232569 Inactive
Karaviloside III 1 umol/L 7.7 10.4 0.35 S K6001 29765490 Active
Karaviloside III 3 umol/L 7.7 10.7 0.39 S K6001 29765490 Active
L-carnitine 1 mM 13 17 21.4 Unclear CML3911A 20550520
LITHOCHOLIC ACID 50 umol/L 105.5 93 S N2 30405886 Active
LITHOCHOLIC ACID 50 umol/L 15 31 1.07 21 42 1 S BY4741 20622262 Active
momordicoside F2 1 umol/L 7.7 11.03 0.43 S K6001 29765490 Active
momordicoside F2 3 umol/L 7.7 9.68 0.26 S K6001 29765490 Active
Momordicoside G 3 umol/L 7.7 10.13 0.32 S K6001 29765490 Active
Momordicoside G 1 umol/L 7.7 9.75 0.27 S K6001 29765490 Active
mycophenolic acid 10 mg/L 23.39 28.56 0.22 S BY4741 32232569 Active
nicotinamide 5 mM 8.9 12.1 0.36 11.6 17.4 0.5 S W303-1A 27320176 Active
nicotinamide 1 mM 8.9 10.7 0.2 11.6 13.9 0.2 S W303-1A 27320176 Active
nicotinamide riboside 10 umol/L 20 S BY4741 17482543 Active
Nolinospiroside F 10 umol/L 6.43 7.8 0.21 S K6001 23439553 Active
Nolinospiroside F 3 umol/L 6.43 7.88 0.23 S K6001 23439553 Active
Nolinospiroside F 1 umol/L 6.43 7.65 0.19 S K6001 23439553 Active
Propionyl-L-Carnitine 1 mM 13 20 42.8 Unclear CML3911A 20550520
3,4-DIHYDROXYBENZOIC ACID 0.002 mg/mL 13 18 0.38 S N2 31792269 Active
quercetin 0.008 mg/mL 13 18 0.38 S N2 31792269 Active
resveratrol 100 umol/L 40 S PSY319AT 12939617 Active
resveratrol 10 umol/L 70 S PSY321AT 12939617 Active
resveratrol 10 umol/L 21.4 30.3 0.42 S PSY316AT 17156081 Active
resveratrol 10 ug/mL 20 S FY631 28727758 Active
resveratrol 10 umol/L 7.8 10.4 0.33 S K6001 32831994 Active
resveratrol 10 umol/L 8.05 11.13 0.38 S K6001 32832008 Active
resveratrol 10 umol/L 60.7 S PSY317AT 12939617 Active
resveratrol 500 umol/L 39.5 S PSY320AT 12939617 Active
resveratrol 10 umol/L 23.3 31.2 0.34 S PSY316AT 17156081 Active
resveratrol 10 umol/L 6.43 7.55 0.17 S K6001 23439553 Active
resveratrol 10 umol/L 7.42 10.2 0.37 S K6001 33510837 Active
resveratrol 10 umol/L 7.35 10.57 0.44 S K6001 31198492 Active
resveratrol 10 umol/L 6.95 9.03 0.3 S K6001 31281576 Active
resveratrol 10 umol/L 70 S 30526767 Active
resveratrol 10 umol/L 7.05 9.05 0.28 S K6001 31281576 Active
resveratrol 10 umol/L 7.8 11.05 0.42 S BY4741 34205671 Active
resveratrol 10 umol/L 5.84 8.49 0.45 S DBY746 32481725 Active
D-Sorbitol 1 M 29.9 S PSY316 12391171 Active
triptolide 10 umol/L 70 S 31201898 Active
3,5-hydroxy-4’-acetoxy-stilbene 10 umol/L 21.4 36 0.68 S PSY316AT 17156081 Active
3,5-hydroxy-4’-ethyl-stilbene 10 umol/L 23.3 35.3 0.52 S PSY316AT 17156081 Active
3,5-hydroxy-4’-thiomethyl-stilbene 10 umol/L 23.3 28.6 0.23 S PSY316AT 17156081 Active
Apple 1 % 78.5 NS MCY4/KlLSM4::kanMX4 22970337 Inactive
Apple flesh 1 % 7 NS MCY4/KlLSM4::kanMX4 22970337 Inactive
Apple peal 1 % 28.5 NS MCY4/KlLSM4::kanMX4 22970337 Inactive
Arabica 0.6 mg/mL 2.2 4 0.82 S BY4741 33327536 Active
bis(4-hydroxybenzyl)ether mono-β-L-galactopyranoside 3 umol/L 11 17 0.55 NS YOM36 31198492 Inactive
bis(4-hydroxybenzyl)ether mono-β-L-galactopyranoside 1 umol/L 7.35 9.93 0.35 S K6001 31198492 Active
bis(4-hydroxybenzyl)ether mono-β-L-galactopyranoside 0.1 umol/L 7.35 8.78 0.19 S K6001 31198492 Active
bis(4-hydroxybenzyl)ether mono-β-L-galactopyranoside 1 umol/L 11 11 0 NS YOM36 31198492 Inactive
bis(4-hydroxybenzyl)ether mono-β-L-galactopyranoside 10 umol/L 7.35 9.69 0.32 S K6001 31198492 Active
bis(4-hydroxybenzyl)ether mono-β-L-galactopyranoside 3 umol/L 7.35 10.13 0.38 S K6001 31198492 Active
Geniposidic 4-isoamyl ester 0.3 umol/L 7.8 10.4 0.33 S BY4741 34205671 Active
Geniposidic 4-isoamyl ester 3 umol/L 7.8 10.5 0.35 S BY4741 34205671 Active
Geniposidic 4-isoamyl ester 1 umol/L 7.8 11.08 0.42 S BY4741 34205671 Active
Hom Dang rice bran extract 0.1 mg/mL 13 18 0.38 S N2 31792269 Active
Robusta 0.6 mg/mL 2.2 2 -0.09 S BY4741 33327536 Inactive
almondskin extract 2 mg/mL 5.84 7.44 0.27 S DBY746 32481725 Active
  Experimental Data Visualization
 Saccharomyces cerevisiae

  Statistics Data
 Saccharomyces cerevisiae

Compound Lifespan Change(AVG/MED%) Lifespan Change(MAX%) Count Reference Count Data point
3,5-hydroxy-4’-acetoxy-stilbene 0.68 1 1
3,5-hydroxy-4’-ethyl-stilbene 0.52 1 1
3,5-hydroxy-4’-thiomethyl-stilbene 0.23 1 1
almondskin extract 0.27 1 1
Apple 78.5 1 1
Apple flesh 7 1 1
Apple peal 28.5 1 1
Arabica 0.82 1 1
bis(4-hydroxybenzyl)ether mono-β-L-galactopyranoside 0.55 1 5
Geniposidic 4-isoamyl ester 0.42 1 3
Hom Dang rice bran extract 0.38 1 1
Robusta -0.09 1 1
Goyaglycoside b 0.44 1 2
Charantagenin E 0.27 1 2
triptolide 70 1 1
L-carnitine 21.4 1 1
Amarogentin 0.36 1 4
guanine -0.03 1 1
Karaviloside III 0.39 1 2
Glyceollin 40 1 1
CHLOROGENIC ACID 0.4 1 3
Propionyl-L-Carnitine 42.8 1 1
charantoside II 0.26 1 2
charantoside IV 0.17 1 2
CHEMBL400981 0.31 1 2
nicotinamide riboside 20 1 1
Inokosterone 0.58 1 5
Goyaglycoside D 0.31 1 2
momordicoside F2 0.43 1 2
resveratrol 70 13 18
mycophenolic acid 0.22 1 1
quercetin 79.72 2 3
butein 31 1 1
Cucurbitacin B 0.38 1 4
Fisetin 55 2 2
4,4'-Dimethoxychalcone 0.33 1 1
D-Sorbitol 29.9 1 1
D-Glc 63.1 1 2
Ehretiquinone 0.43 1 5
xylitol 36.8 1 1
Acetyl-L-carnitine 62.4 1 1
3,4-DIHYDROXYBENZOIC ACID 0.38 1 1
glycerol 49.8 1 1
Nolinospiroside F 0.23 1 3
Gentiopicroside 0.41 1 4
Momordicoside G 0.32 1 2
nicotinamide 0.36 0.5 1 2
LITHOCHOLIC ACID 105.5 93 2 2
  Statistics Data Visualization
 Saccharomyces cerevisiae

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