Compound Summary
Compound Information
mycophenolic acid
Compound Name: | mycophenolic acid |
Compound CID: | 446541 |
Synonyms: | mycophenolic acid 24280-93-1 Mycophenolate Melbex Myfortic More... |
Iupac Name: | (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoic acid |
InChI: | InChI=1S/C17H20O6/c1-9(5-7-13(18)19)4-6-11-15(20)14-12(8-23-17(14)21)10(2)16(11)22-3/h4,20H,5-8H2,1-3H3,(H,18,19)/b9-4+ |
InChIKey: | HPNSFSBZBAHARI-RUDMXATFSA-N |
Canonical Smiles: | CC1=C2COC(=O)C2=C(C(=C1OC)CC=C(C)CCC(=O)O)O |
Isomeric Smiles: | CC1=C2COC(=O)C2=C(C(=C1OC)C/C=C(\C)/CCC(=O)O)O |
Molecular Weight: | 320.3 |
Molecular Formula: | C17H20O6 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
mycophenolic acid
Molecular Weight: | 320.3 |
Molecular Formula: | C17H20O6 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 6 |
Rotatable Bond Count: | 6 |
Heavy Atom Count: | 23 |
Complexity: | 486 |
Synonyms
mycophenolic acid
| mycophenolic acid | mycophenolic acid |
|---|---|
mycophenolic acid |
24280-93-1 |
Mycophenolate |
Melbex |
Myfortic |
Mycophenolsaeure |
Lilly-68618 |
6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid |
483-60-3 |
Acido micofenolico |
Micofenolico acido |
NSC-129185 |
Acide mycophenolique |
Acidum mycophenolicum |
(4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoic acid |
CCRIS 5565 |
NSC 129185 |
UNII-HU9DX48N0T |
(E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoic acid |
Ly 68618 |
(E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid |
(E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoic acid |
6-(1,3-Dihydro-7-hydroxy-5-methoxy-4-methyl-1-oxoisobenzofuran-6-yl)-4-methyl-4-hexanoic acid |
MFCD00036814 |
Lilly 68618 |
CHEMBL866 |
HU9DX48N0T |
CHEBI:168396 |
TNP00198 |
RS-61443 AS MOFETIL |
NSC129185 |
4-Hexenoic acid, 6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-, (E)- |
4-Methyl-5-methoxy-7-hydroxy-6-(5-carboxy-3-methylpent-2-en-1-yl)-phthalide (E)- |
6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid (E)- |
4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, (E)- |
NCGC00016786-01 |
CAS-24280-93-1 |
6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methylhex-4-enoic acid |
DSSTox_CID_21070 |
DSSTox_RID_79619 |
DSSTox_GSID_41070 |
(E)-6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic acid |
Mycophenolic acid-d3 solution |
Mycophenoic acid |
Micofenolico acido Spanish |
(4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxohydroisobenzofuran-5-yl)-4-methylhex -4-enoic acid |
6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic acid |
MOA |
SMR000471887 |
Acido micofenolico INN-Spanish |
Acide mycophenolique INN-French |
Acidum mycophenolicum INN-Latin |
SR-01000597602 |
EINECS 246-119-3 |
mycophenolic-acid |
6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-isobenzofuran-5-yl)-4-methyl-4-hexenoic acid |
Prestwick_817 |
EINECS 207-595-8 |
Mycophenolic acid USAN:INN:BAN |
Tocris-1505 |
(Z)-Mycophenolic Acid |
1jr1 |
Mycophenolic acid (TN) |
Prestwick2_000556 |
Prestwick3_000556 |
Spectrum5_001654 |
Mycophenolic Acid (MPA) |
Mycophenolic acid solution |
UPCMLD-DP028 |
4-Hexenoic acid, (E)- |
EC 246-119-3 |
Mycophenolate;RS-61443 |
SCHEMBL4549 |
Mycophenolic (Mycophenolate) |
Mycophenolic acid, >=98% |
BSPBio_000631 |
BSPBio_002534 |
MLS001074701 |
MLS002222265 |
MLS002695945 |
BIDD:GT0456 |
SPECTRUM1500674 |
BPBio1_000695 |
GTPL6832 |
MEGxm0_000120 |
Mycophenolic acid (USAN/INN) |
Myfortic (mycophenolate sodium) |
SCHEMBL2514376 |
ZINC1758 |
DTXSID4041070 |
UPCMLD-DP028:001 |
ACon0_000960 |
ACon1_000496 |
BDBM19264 |
CHEBI:92545 |
HMS500H08 |
AOB5506 |
EX-A975 |
HMS1569P13 |
HMS1921A18 |
HMS2089A17 |
HMS2092G22 |
HMS2096P13 |
HMS2268H22 |
HMS3403P09 |
HMS3412F09 |
HMS3676F09 |
Pharmakon1600-01500674 |
ACT02623 |
AMY40494 |
BCP05321 |
HY-B0421 |
Tox21_110610 |
BBL034696 |
CCG-39914 |
NSC757424 |
s2487 |
STL419986 |
Mycophenolic acid, analytical standard |
AKOS015888214 |
Tox21_110610_1 |
AC-4491 |
BCP9000970 |
DB01024 |
DS-1638 |
MCULE-1991681277 |
NSC-757424 |
SDCCGMLS-0066618.P001 |
(E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-isobenzofuran-5-yl)-4-methyl-hex-4-enoic acid |
IDI1_000146 |
NCGC00016786-02 |
NCGC00016786-03 |
NCGC00016786-04 |
NCGC00016786-05 |
NCGC00016786-06 |
NCGC00016786-07 |
NCGC00016786-08 |
NCGC00016786-09 |
NCGC00016786-10 |
NCGC00016786-11 |
NCGC00016786-12 |
NCGC00016786-15 |
NCGC00025190-01 |
NCGC00025190-02 |
NCGC00025190-03 |
NCGC00025190-04 |
NCGC00025190-05 |
NCGC00025190-07 |
NCGC00025190-08 |
NCGC00025190-09 |
NCGC00025190-10 |
4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, (4E)- |
BM164624 |
ST044516 |
Mycophenolic Acid - CAS 24280-93-1 |
SBI-0051945.P003 |
AB0011511 |
A-249 |
M2216 |
SW196951-2 |
C20380 |
D05096 |
M 5255 |
M02087 |
AB00052466-13 |
AB00052466-14 |
AB00052466_15 |
AB00052466_16 |
Mycophenolic acid 100 microg/mL in Acetonitrile |
280M931 |
A817192 |
Mycophenolate mofetil impurity, mycophenolic acid- |
Q420553 |
SR-01000597602-1 |
SR-01000597602-3 |
SR-01000597602-4 |
BRD-K63750851-001-06-6 |
BRD-K63750851-001-13-2 |
Mycophenolic acid, powder, BioReagent, suitable for cell culture, >=98% |
6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthanlanyl)-4-methyl-4-hexanoic acid |
(4E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoic Acid (Mycophenolic Acid) |
(E)-6-(1,3-dihydro-4-hydroxy-6- methoxy-7-methyl-3-oxoisobenzofuran-5-yl)-4-methyl-4-hexenoic acid |
(E)-6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxoisobenzofuran-5-yl)-4-methyl-4-hexenoic acid |
1162256-90-7 |
4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, (4E)- (9CI) |
4-Hexenoic acid, 6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-, (E)- (8CI) |
4-Hexenoic acid,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5- isobenzofuranyl)-4-methyl-, (E)- |
4-Hexenoic acid,6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, (4E)- |
4-Methyl-6-3-oxo-7-methyl-4-hydroxy-6-methoxy-1,3-dihydroisobenzofuran-5-yl-4-hexenoic acid |
6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoic acid |
E-6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic acid |
Mycophenolic acid solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material |
Experimental Data
mycophenolic acid
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 10 | umol/L | 17.01 | 17.05 | 0.2381 | NS | N2 | 33008901 | Inactive | ||||
| Drosophila melanogaster | 200 | umol/L | 43.17 | 45.79 | 6.085 | NS | MALES | 33008901 | Inactive | ||||
| Drosophila melanogaster | 20 | umol/L | 44.63 | 50.74 | 13.7 | S | FEMALES | 33008901 | Active | ||||
| Caenorhabditis elegans | 100 | umol/L | 15.78 | 15.9 | 0.8207 | NS | N2 | 33008901 | Inactive | ||||
| Saccharomyces cerevisiae | 10 | mg/L | 23.39 | 28.56 | 0.22 | S | BY4741 | 32232569 | Active |
Experimental Data Visualization
mycophenolic acid
Statistics Data
mycophenolic acid
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 0.8207 | 1 | 2 | |
| Drosophila melanogaster | 13.7 | 1 | 2 | |
| Saccharomyces cerevisiae | 0.22 | 1 | 1 |
Statistics Data Visualization
mycophenolic acid
