Compound Summary
Compound Information
nicotinamide riboside
Compound Name: | nicotinamide riboside |
Compound CID: | 439924 |
Synonyms: | nicotinamide riboside nicotinamide ribose 1341-23-7 N-ribosylnicotinamide nicotinamide-beta-riboside More... |
Iupac Name: | 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyridin-1-ium-3-carboxamide |
InChI: | InChI=1S/C11H14N2O5/c12-10(17)6-2-1-3-13(4-6)11-9(16)8(15)7(5-14)18-11/h1-4,7-9,11,14-16H,5H2,(H-,12,17)/p+1/t7-,8-,9-,11-/m1/s1 |
InChIKey: | JLEBZPBDRKPWTD-TURQNECASA-O |
Canonical Smiles: | C1=CC(=C[N+](=C1)C2C(C(C(O2)CO)O)O)C(=O)N |
Isomeric Smiles: | C1=CC(=C[N+](=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)C(=O)N |
Molecular Weight: | 255.25 |
Molecular Formula: | C11H15N2O5+ |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
nicotinamide riboside
Molecular Weight: | 255.25 |
Molecular Formula: | C11H15N2O5+ |
Hydrogen Bond Donor Count: | 4 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 3 |
Heavy Atom Count: | 18 |
Complexity: | 314 |
Synonyms
nicotinamide riboside
| nicotinamide riboside | nicotinamide riboside |
|---|---|
nicotinamide riboside |
nicotinamide ribose |
1341-23-7 |
N-ribosylnicotinamide |
nicotinamide-beta-riboside |
nicotinamide ribonucleoside |
ribosylnicotinamide |
1-(beta-D-Ribofuranosyl)nicotinamide |
UNII-0I8H2M0L7N |
3-Carbamoyl-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridin-1-ium |
0I8H2M0L7N |
CHEBI:15927 |
1-(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-ylpyridin-1-ium-3-carboxamide |
Pyridinium, 3-(aminocarbonyl)-1-beta-D-ribofuranosyl- |
3-carbamoyl-1-beta-D-ribofuranosylpyridinium |
Niagen |
TruNiagen |
SRT647 |
SRT 647 |
SRT-647 |
N-ribosyl-nicotinamide |
beta-nicotinamide D-riboside |
N-Ribosyl-Nicotinamide New |
SCHEMBL938611 |
CHEMBL438497 |
C12H15F3N2O8S |
DTXSID501010039 |
ZINC4096036 |
1-(beta-D ribofuranosyl)nicotinamide |
1-b-D-ribosyl-3-Pyridinecarboxamide |
1-beta-D-ribosyl-3-Pyridinecarboxamide |
AM84366 |
DB14933 |
1-beta-delta-ribosyl-3-Pyridinecarboxamide |
AB0072017 |
HY-123033 |
CS-0080934 |
Z5778 |
C03150 |
3-(aminocarbonyl)-1-beta-d-ribofuranosylpyridinium |
3-(aminocarbonyl)-1beta-d-ribofuranosylpyridinium |
3-(aminocarbonyl)-1-beta-D-ribofuranosyl-Pyridinium |
Q3334152 |
3-(aminocarbonyl)-1-beta-delta-ribofuranosyl-Pyridinium |
3-carbamoyl-1-(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl-1$l^{5}-pyridin-1-ylium |
Experimental Data
nicotinamide riboside
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mus musculus | 1000 | ppm | 787 | 763 | -3 | 1047 | 1019 | -3 | NS | C57BL/6 J | MALES | 33788371 | Inactive |
| Mus musculus | 1000 | ppm | 874 | 875 | 0 | 1047 | 1068 | 2 | NS | C57BL/6 J | FEMALES | 33788371 | Inactive |
| Mus musculus | 400 | mg/kg | 829 | 868 | 0.05 | S | C57BL/6J | 27127236 | Active | ||||
| Saccharomyces cerevisiae | 10 | umol/L | 20 | S | BY4741 | 17482543 | Active |
Experimental Data Visualization
nicotinamide riboside
Statistics Data
nicotinamide riboside
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Mus musculus | 0.05 | 2 | 2 | 3 |
| Saccharomyces cerevisiae | 20 | 1 | 1 |
Statistics Data Visualization
nicotinamide riboside
