Compound Summary
trimethadione
Compound Information
trimethadione
Compound Name: | trimethadione |
Compound CID: | 5576 |
Synonyms: | trimethadione 127-48-0 Tridione Troxidone Trimetadione More... |
Iupac Name: | 3,5,5-trimethyl-1,3-oxazolidine-2,4-dione |
InChI: | InChI=1S/C6H9NO3/c1-6(2)4(8)7(3)5(9)10-6/h1-3H3 |
InChIKey: | IRYJRGCIQBGHIV-UHFFFAOYSA-N |
Canonical Smiles: | CC1(C(=O)N(C(=O)O1)C)C |
Isomeric Smiles: | CC1(C(=O)N(C(=O)O1)C)C |
Molecular Weight: | 143.14 |
Molecular Formula: | C6H9NO3 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
trimethadione
Molecular Weight: | 143.14 |
Molecular Formula: | C6H9NO3 |
Hydrogen Bond Donor Count: | 0 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 0 |
Heavy Atom Count: | 10 |
Complexity: | 197 |
Synonyms
trimethadione
| trimethadione | trimethadione |
|---|---|
trimethadione |
127-48-0 |
Tridione |
Troxidone |
Trimetadione |
Trimethadion |
Trimetin |
Absentol |
Convenixa |
Convexina |
Epidione |
Petidion |
Petimalin |
Tioxanona |
Tridilona |
Trimedal |
Trimethin |
Trioxanona |
Absetil |
Epixal |
Petidon |
Petilep |
Ptimal |
Tridion |
Edion |
Minoaleviatin |
Trimethdione |
2,4-OXAZOLIDINEDIONE, 3,5,5-TRIMETHYL- |
Minoaleuiatin |
3,5,5-Trimethyl-1,3-oxazolidine-2,4-dione |
Tredione |
Tricione |
Trilidona |
Trimedone |
Triozanona |
Tromedone |
Epidone |
Etydion |
Pitmal |
Tridone |
3,5,5-Trimethyloxazolidine-2,4-dione |
Mino-Aleviatin |
3,5,5-Trimethyl-2,4-oxazolidinedione |
3,5,5,-Trimethyloxazolidine-2,4-dione |
A 2297 |
3,3,5-Trimethyl-2,4-diketooxazolidine |
UNII-R7GV3H6FQ4 |
NSC 15799 |
3,5,5-Trojmetylooksazolidyno-2,4-dion |
R7GV3H6FQ4 |
Trimethinum |
Trioksal |
3,5,5-TRIMETHYL-OXAZOLIDINE-2,4-DIONE |
trimethyl-1,3-oxazolidine-2,4-dione |
NCGC00016383-01 |
Trimetadiona |
Trimethadionum |
CAS-127-48-0 |
Trimetadione DCIT |
DSSTox_CID_1396 |
2, 3,5,5-trimethyl- |
DSSTox_RID_76137 |
DSSTox_GSID_21396 |
Trimetadiona INN-Spanish |
Trimethadionum INN-Latin |
3,5-Trimethyl-2,4-oxazolidinedione |
3,5-Trimethyl-2,4-diketooxazolidine |
WLN: T5OVNV EHJ C1 E1 E1 |
Tridione (TN) |
EINECS 204-845-8 |
3,5,5-Trojmetylooksazolidyno-2,4-dion Polish |
BRN 0121627 |
Mino aleviatin |
Tridione Dulcet |
Trimethadione USP:INN:BAN:JAN |
Prestwick_815 |
MFCD00047084 |
ACMC-1BYOW |
Prestwick0_000515 |
Prestwick1_000515 |
Prestwick2_000515 |
Prestwick3_000515 |
CHEMBL695 |
Trimethadione (JP17/INN) |
SCHEMBL28882 |
BSPBio_000469 |
MLS001076685 |
SPBio_002390 |
BPBio1_000517 |
CHEBI:9727 |
GTPL7316 |
DTXSID9021396 |
IRYJRGCIQBGHIV-UHFFFAOYSA- |
HMS1569H11 |
HMS2093D10 |
HMS2096H11 |
HMS2235E12 |
HMS3713H11 |
HMS3886I12 |
Pharmakon1600-01505466 |
HY-A0092 |
NSC15799 |
ZINC1530710 |
Tox21_110408 |
Tox21_200231 |
BDBM50227239 |
NSC-15799 |
NSC169503 |
NSC759152 |
s5567 |
Trimethadione 1.0 mg/ml in Methanol |
AKOS006229172 |
CCG-213460 |
DB00347 |
MCULE-4761457520 |
NSC-169503 |
NSC-759152 |
3,5,5-Trimethyl oxazolidine-2,4-dione |
NCGC00016383-02 |
NCGC00016383-03 |
NCGC00016383-05 |
NCGC00257785-01 |
BS-15128 |
SMR000499583 |
SBI-0206923.P001 |
FT-0694585 |
ST50411784 |
D00392 |
D84162 |
20503-EP2275420A1 |
20503-EP2280008A2 |
20503-EP2298764A1 |
20503-EP2298765A1 |
20503-EP2308867A2 |
20503-EP2308870A2 |
20503-EP2314585A1 |
3,5,5-Trimethyl-1,3-oxazolidine-2,4-dione # |
Q827916 |
SR-01000763540 |
J-005496 |
SR-01000763540-2 |
BRD-K16606819-001-07-7 |
3,5,5,-Trimethyloxazolidine-2,4-dione, analytical standard |
Trimethadione, European Pharmacopoeia (EP) Reference Standard |
Trimethadione, United States Pharmacopeia (USP) Reference Standard |
Experimental Data
trimethadione
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 10.000000000000000 | mM | Unclear | N2 | 33683565 | ||||||||
| Caenorhabditis elegans | 10.000000000000000 | mM | Unclear | N2 | 33683565 | ||||||||
| Caenorhabditis elegans | 5.000000000000000 | mM | Unclear | N2 | 33683565 | ||||||||
| Caenorhabditis elegans | 5.000000000000000 | mM | Unclear | N2 | 33683565 | ||||||||
| Caenorhabditis elegans | 50.000000000000000 | mM | Unclear | N2 | 33683565 | ||||||||
| Caenorhabditis elegans | 50.000000000000000 | mM | Unclear | N2 | 33683565 | ||||||||
| Caenorhabditis elegans | 4.000000000000000 | mg/mL | 16.700000000000000 | 15.500000000000000 | -7.000000000000000 | 23.300000000000000 | 21.000000000000000 | -10.000000000000000 | Unclear | N2 | 15653505 | Inactive | |
| Caenorhabditis elegans | 28.000000000000000 | mM | 16.200000000000000 | 23.500000000000000 | 45.000000000000000 | 23.300000000000000 | 36.900000000000000 | 58.000000000000000 | S | N2 | 18248662 | Active | |
| Caenorhabditis elegans | 4.000000000000000 | mg/mL | -7.000000000000000 | -10.000000000000000 | NS | N2 | 33683565 | Inactive | |||||
| Caenorhabditis elegans | 4.000000000000000 | mg/mL | 47.000000000000000 | 57.000000000000000 | S | N2 | 33683565 | Active | |||||
| Caenorhabditis elegans | 4.000000000000000 | mg/mL | 24.000000000000000 | 29.000000000000000 | S | N2 | 33683565 | Active | |||||
| Caenorhabditis elegans | 4.000000000000000 | mg/mL | 16.700000000000000 | 24.600000000000000 | 47.000000000000000 | 23.300000000000000 | 36.500000000000000 | 57.000000000000000 | S | N2 | 15653505 | Active | |
| Caenorhabditis elegans | 32.000000000000000 | S | N2 | 16872777 | Active | ||||||||
| Caenorhabditis elegans | 4.000000000000000 | mg/mL | 41.000000000000000 | 23.000000000000000 | S | N2 | 33683565 | Active | |||||
| Caenorhabditis elegans | 4.000000000000000 | mg/mL | 39.000000000000000 | 33.000000000000000 | S | N2 | 33683565 | Active | |||||
| Caenorhabditis elegans | 4.000000000000000 | mg/mL | 16.700000000000000 | 20.700000000000000 | 24.000000000000000 | 23.300000000000000 | 30.100000000000000 | 29.000000000000000 | S | N2 | 15653505 | Active |
Experimental Data Visualization
trimethadione
Statistics Data
trimethadione
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 47.000000000000000 | 58.000000000000000 | 4 | 16 |
Statistics Data Visualization
trimethadione
