Compound Summary

terfenadine
  Compound Information
 terfenadine

Compound Name:

terfenadine

Compound CID:

5405

Synonyms:

terfenadine

50679-08-8

Seldane

Ternadin

Triludan

More...

Iupac Name:

1-(4-tert-butylphenyl)-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butan-1-ol

InChI:

InChI=1S/C32H41NO2/c1-31(2,3)26-18-16-25(17-19-26)30(34)15-10-22-33-23-20-29(21-24-33)32(35,27-11-6-4-7-12-27)28-13-8-5-9-14-28/h4-9,11-14,16-19,29-30,34-35H,10,15,20-24H2,1-3H3

InChIKey:

GUGOEEXESWIERI-UHFFFAOYSA-N

Canonical Smiles:

CC(C)(C)C1=CC=C(C=C1)C(CCCN2CCC(CC2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O)O

Isomeric Smiles:

CC(C)(C)C1=CC=C(C=C1)C(CCCN2CCC(CC2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O)O

Molecular Weight:

471.7

Molecular Formula:

C32H41NO2

  Compound Structure
 2D Structure:
 3D Structure:
  Computed Properties
 terfenadine

Molecular Weight:

471.7

Molecular Formula:

C32H41NO2

Hydrogen Bond Donor Count:

2

Hydrogen Bond Acceptor Count:

3

Rotatable Bond Count:

9

Heavy Atom Count:

35

Complexity:

582

  Synonyms
 terfenadine

terfenadine terfenadine

terfenadine

50679-08-8

Seldane

Ternadin

Triludan

Teldane

Allerplus

Teldanex

Aldaban

Terdin

Terfenadina

RMI 9918

RMI-9918

1-(4-(tert-butyl)phenyl)-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butan-1-ol

1-(4-tert-butylphenyl)-4-4-hydroxy(diphenyl)methylpiperidin-1-ylbutan-1-ol

alpha-4-(1,1-Dimethylethyl)phenyl-4-(hydroxydiphenylmethyl)-1-piperidinebutanol

MDL-9918

MFCD00079622

CHEMBL17157

MLS000028499

CHEBI:9453

Cyater

Terfen

alpha-(4-(1,1-Dimethylethyl)phenyl)-4-(hydroxydiphenylmethyl)-1-piperidinebutanol

1-Piperidinebutanol, .alpha.-4-(1,1-dimethylethyl)phenyl-4-(hydroxydiphenylmethyl)-

NCGC00016064-04

NCGC00016064-06

Terfenadinum

SMR000058260

Terfex

DSSTox_CID_3642

1-(4-tert-butylphenyl)-4-4-(hydroxydiphenylmethyl)piperidin-1-ylbutan-1-ol

1-(4-(tert-Butyl)phenyl)-4-(4-(hydroxydiphenylmethyl)-piperidin-1-yl)butan-1-ol

DSSTox_RID_77124

DSSTox_GSID_23642

Terfenadinum INN-Latin

Terfenadina INN-Spanish

C32H41NO2

1-(4-tert-butylphenyl)-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butan-1-ol

MDL 9918

alpha-(4-1,1-Dimethylethylphenyl)-4-hydroxydiphenylmethyl-1-piperidinebutanol

Seldane (TN)

HSDB 6508

SR-01000000104

EINECS 256-710-8

BRN 5857899

teraenadine

UNII-7BA5G9Y06Q

Terfenadin

Terfenadine (JAN/USAN/INN)

Terfenadine,(S)

(-)-Terfenadine

alpha-(p-tert-Butylphenyl)-4-(hydroxydiphenylmethyl)-1-piperidinebutanol

Prestwick_460

1-(4-tert-Butylphenyl)-4-(4-(alpha-hydroxybenzhydryl)piperidino)-butan-1-ol

1-(p-tert-Butylphenyl)-4-(4-(alpha-hydroxydiphenylmethyl)-1-piperidyl)butanol

CAS-50679-08-8

1-Piperidinebutanol, alpha-(4-(1,1-dimethylethyl)phenyl)-4-(hydroxydiphenylmethyl)-

Terfenadine USAN:USP:INN:BAN:JAN

Opera_ID_334

Prestwick0_000138

Prestwick1_000138

Prestwick2_000138

Prestwick3_000138

(.+/-.)-Terfenadine

T 9652

SCHEMBL5152

Lopac0_001213

Oprea1_343139

BSPBio_000216

MLS001148415

DivK1c_001011

SPBio_002155

7BA5G9Y06Q

BPBio1_000238

GTPL2608

DTXSID2023642

HMS503K03

KBio1_001011

MDL-991

NINDS_001011

HMS1568K18

HMS2089I14

HMS2093I11

HMS2095K18

HMS2231N07

HMS3263D08

HMS3373J07

HMS3712K18

Pharmakon1600-01503708

HY-B1193

Tox21_110295

Tox21_110296

Tox21_501213

AC-928

BDBM50017376

NSC665802

NSC758627

s4353

AKOS015962091

Tox21_110295_1

CCG-205287

CS-4800

DB00342

LP01213

MCULE-8216311776

NSC 665802

NSC 758627

NSC-665802

NSC-758627

SDCCGSBI-0051180.P004

VA11848

1-(4-tert-butylphenyl)-4-4-hydroxy(diphenyl)methyl-1-piperidylbutan-1-ol

1-4-(1,1-dimethylethyl)phenyl-4-{4-hydroxy(diphenyl)methylpiperidin-1-yl}butan-1-ol

IDI1_001011

NCGC00016064-03

NCGC00016064-05

NCGC00016064-08

NCGC00016064-09

NCGC00016064-12

NCGC00016064-19

NCGC00089746-02

NCGC00089746-03

NCGC00089746-04

NCGC00261898-01

( inverted exclamation markA)-Terfenadine

AC-15791

AS-75636

BT166253

NCI60_022784

SBI-0051180.P003

DB-051821

AB00052367

EU-0101213

FT-0630637

ST50307835

SW196677-3

BIM-0051180.0001

C07463

D00521

D82079

AB00052367-16

AB00052367_17

AB00052367_18

A828247

L000888

Q417909

( inverted exclamation markA)-Terfenadine;MDL-991

( inverted exclamation markA)-Terfenadine;MDL-9918

SR-01000000104-2

SR-01000000104-4

SR-01000000104-7

BRD-A06352418-001-03-6

BRD-A06352418-001-15-0

Terfenadine, European Pharmacopoeia (EP) Reference Standard

Terfenadine, United States Pharmacopeia (USP) Reference Standard

.alpha.-(p-tert-Butylphenyl)-4-(hydroxydiphenylmethyl)-1-piperidinebutanol

1-4-(tert-butyl)phenyl-4-4-(hydroxydiphenylmethyl)piperidylbutan-1-ol

(+/-)1-(4-tert-butylphenyl)-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butan-1-ol

(RS)-1-(4-tert-butylphenyl)-4-{4-hydroxy(diphenyl)methylpiperidin-1-yl}-butan-1-ol

.alpha.-(4-(1,1-dimethylethyl)phenyl)-4-(hydroxydiphenyl-methyl)-1-piperidine butanol

.alpha.-(4-(1,1-Dimethylethyl)phenyl)-4-(hydroxydiphenylmethyl)-1-piperidinebutanol

1-(4-tert-Butyl-phenyl)-4-4-(hydroxy-diphenyl-methyl)-piperidin-1-yl-butan-1-ol

1-(4-tert-Butylphenyl)-4-(4-hydroxy(diphenyl)methyl-1-piperidinyl)-1-butanol #

1-(4-tert-butylphenyl)-4-4-hydroxy-di(phenyl)methylpiperidin-1-ylbutan-1-ol

a-4-(1,1-Dimethylethyl)phenyl-4-(hydroxydiphenylmethyl)-1-piperidinebutanol

1-(4-tert-Butyl-phenyl)-4-4-(hydroxy-diphenyl-methyl)-piperidin-1-yl-butan-1-ol(Terfenadine)

  Experimental Data
 terfenadine

Species Dose Unit Control(Avg days) Treatment(Avg days) Avg/Med Lifespan Change(%) Control(Max days) Treatment(Max days) Max Lifespan Change(%) Significant Strain Gender PubMed Avg/Med Lifespan Change tab
Caenorhabditis elegans 33.000000000000000 umol/L 43.000000000000000 NS N2 24134630 Inactive
  Experimental Data Visualization
 terfenadine

  Statistics Data
 terfenadine

Species Avg/Med Lifespan Change(%) Max Lifespan Change(%) Count Reference Count Data point
Caenorhabditis elegans 43.000000000000000 1 1
  Statistics Data Visualization
 terfenadine

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