Compound Summary
t-0156
Compound Information
t-0156
Compound Name: | t-0156 |
Compound CID: | 5368 |
Synonyms: | t-0156 T0156 CHEMBL540294 methyl 2-(2-methylpyridin-4-yl)methyl-1-oxo-8-(pyrimidin-2-ylmethoxy)-4-(3,4,5-trimethoxyphenyl)-1,2-dihydro-2,7-naphthyridine-3-carboxylate Methyl 2-((2-methylpyridin-4-yl)methyl)-1-oxo-8-(pyrimidin-2-ylmethoxy)-4-(3,4,5-trimethoxyphenyl)-1,2-dihydro-2,7-naphthyridine-3-carboxylate More... |
Iupac Name: | methyl 2-[(2-methylpyridin-4-yl)methyl]-1-oxo-8-(pyrimidin-2-ylmethoxy)-4-(3,4,5-trimethoxyphenyl)-2,7-naphthyridine-3-carboxylate |
InChI: | InChI=1S/C31H29N5O7/c1-18-13-19(7-11-32-18)16-36-27(31(38)42-5)25(20-14-22(39-2)28(41-4)23(15-20)40-3)21-8-12-35-29(26(21)30(36)37)43-17-24-33-9-6-10-34-24/h6-15H,16-17H2,1-5H3 |
InChIKey: | JEMJAABFSYOLAP-UHFFFAOYSA-N |
Canonical Smiles: | CC1=NC=CC(=C1)CN2C(=C(C3=C(C2=O)C(=NC=C3)OCC4=NC=CC=N4)C5=CC(=C(C(=C5)OC)OC)OC)C(=O)OC |
Isomeric Smiles: | CC1=NC=CC(=C1)CN2C(=C(C3=C(C2=O)C(=NC=C3)OCC4=NC=CC=N4)C5=CC(=C(C(=C5)OC)OC)OC)C(=O)OC |
Molecular Weight: | 583.6 |
Molecular Formula: | C31H29N5O7 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
t-0156
Molecular Weight: | 583.6 |
Molecular Formula: | C31H29N5O7 |
Hydrogen Bond Donor Count: | 0 |
Hydrogen Bond Acceptor Count: | 11 |
Rotatable Bond Count: | 11 |
Heavy Atom Count: | 43 |
Complexity: | 978 |
Synonyms
t-0156
| t-0156 | t-0156 |
|---|---|
t-0156 |
T0156 |
CHEMBL540294 |
methyl 2-(2-methylpyridin-4-yl)methyl-1-oxo-8-(pyrimidin-2-ylmethoxy)-4-(3,4,5-trimethoxyphenyl)-1,2-dihydro-2,7-naphthyridine-3-carboxylate |
Methyl 2-((2-methylpyridin-4-yl)methyl)-1-oxo-8-(pyrimidin-2-ylmethoxy)-4-(3,4,5-trimethoxyphenyl)-1,2-dihydro-2,7-naphthyridine-3-carboxylate |
NCGC00016057-01 |
Tocris-1676 |
Lopac-T-8067 |
Lopac0_001212 |
SCHEMBL687326 |
GTPL5275 |
CHEMBL1190161 |
CHEBI:93111 |
ZINC3963610 |
BDBM50130017 |
HSCI1_000141 |
CCG-205286 |
NCGC00016057-02 |
NCGC00016057-03 |
NCGC00025257-01 |
NCGC00025257-02 |
BRD-K63516691-001-01-6 |
BRD-K63516691-003-01-2 |
Q27088906 |
1-Oxo-2-(2-methyl-4-pyridinylmethyl)-4-(3,4,5-trimethoxyphenyl)-8-(2-pyrimidinylmethoxy)-1,2-dihydro-2,7-naphthyridine-3-carboxylic acid methyl ester |
2-(2-Methyl-pyridin-4-ylmethyl)-1-oxo-8-(pyrimidin-2-ylmethoxy)-4-(3,4,5-trimethoxy-phenyl)-1,2-dihydro-2,7naphthyridine-3-carboxylic acid methyl ester; hydrochloride |
324572-92-1 |
Experimental Data
t-0156
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | 4.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
t-0156
Statistics Data
t-0156
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 4.000000000000000 | 1 | 1 |
Statistics Data Visualization
t-0156
