Compound Summary

pimozide
  Compound Information
 pimozide

Compound Name:

pimozide

Compound CID:

16362

Synonyms:

pimozide

2062-78-4

Orap

Opiran

Pimozidum

More...

Iupac Name:

3-[1-[4,4-bis(4-fluorophenyl)butyl]piperidin-4-yl]-1H-benzimidazol-2-one

InChI:

InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34)

InChIKey:

YVUQSNJEYSNKRX-UHFFFAOYSA-N

Canonical Smiles:

C1CN(CCC1N2C3=CC=CC=C3NC2=O)CCCC(C4=CC=C(C=C4)F)C5=CC=C(C=C5)F

Isomeric Smiles:

C1CN(CCC1N2C3=CC=CC=C3NC2=O)CCCC(C4=CC=C(C=C4)F)C5=CC=C(C=C5)F

Molecular Weight:

461.5

Molecular Formula:

C28H29F2N3O

  Compound Structure
 2D Structure:
 3D Structure:
  Computed Properties
 pimozide

Molecular Weight:

461.5

Molecular Formula:

C28H29F2N3O

Hydrogen Bond Donor Count:

1

Hydrogen Bond Acceptor Count:

4

Rotatable Bond Count:

7

Heavy Atom Count:

34

Complexity:

632

  Synonyms
 pimozide

pimozide pimozide

pimozide

2062-78-4

Orap

Opiran

Pimozidum

Pimozidum INN-Latin

McN-JR-6238

R-6238

R 6238

R6238

UNII-1HIZ4DL86F

NSC 170984

McN-JR 6238

3-1-4,4-bis(4-fluorophenyl)butylpiperidin-4-yl-1H-benzimidazol-2-one

2H-Benzimidazol-2-one, 1-1-4,4-bis(4-fluorophenyl)butyl-4-piperidinyl-1,3-dihydro-

1-(1-(4,4-Bis(p-fluorophenyl)butyl)-4-piperidyl)-2-benzimidazolinone

1-1-4,4-Bis(p-fluorophenyl)butyl-4-piperidyl-2-benzimidazolinone

1HIZ4DL86F

CHEMBL1423

1-(4,4-Bis(p-fluorophenyl)butyl)-4-(2-oxo-1-benzimidazolinyl)piperidine

1-1-4,4-bis(4-Fluorophenyl)butyl-4-piperidinyl-1,3-dihydro-2H-benzimidazol-2-one

MLS000028410

MLS002702058

CHEBI:8212

MFCD00055081

NSC170984

1-{1-4,4-bis(4-fluorophenyl)butylpiperidin-4-yl}-1,3-dihydro-2H-benzimidazol-2-one

1-{1-4,4-bis(4-fluorophenyl)butylpiperidin-4-yl}-2,3-dihydro-1H-1,3-benzodiazol-2-one

2H-Benzimidazol-2-one, 1-(1-(4,4-bis(4-fluorophenyl)butyl)-4-piperidinyl)-1,3-dihydro-

NSC-170984

NCGC00015802-08

NCGC00015802-18

Primozida

SMR000058385

CAS-2062-78-4

DSSTox_CID_3474

1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)-1H-benzodimidazol-2(3H)-one

DSSTox_RID_77042

DSSTox_GSID_23474

Primozida INN-Spanish

pimozida

Primozide

C28H29F2N3O

Pimozida INN-Spanish

1-4,4-Bis(p-fluorophenyl)butyl-4-(2-oxo-1-benzimidazolinyl)piperidine

CCRIS 9172

Orap (TN)

SR-01000075392

EINECS 218-171-7

BRN 0729089

1-(1-(4,4-bis(4-fluorophenyl)butyl)-4-piperidinyl)-1,3-dihydro-2H-benzimidazol-2-one

Prestwick_395

Pimozide USAN:USP:INN:BAN:JAN

Spectrum_000445

Tocris-0937

Opera_ID_1580

Prestwick0_000308

Prestwick1_000308

Prestwick2_000308

Prestwick3_000308

Spectrum2_001026

Spectrum3_001451

Spectrum4_000420

Spectrum5_001308

Lopac-P-1793

GTPL90

NCIMech_000356

P 1793

Lopac0_000946

SCHEMBL41584

BSPBio_000276

BSPBio_001439

BSPBio_002941

KBioGR_000720

KBioSS_000925

5-24-02-00367 (Beilstein Handbook Reference)

MLS001077311

BIDD:GT0435

DivK1c_000386

Methyl-(2-m-tolylethyl)amine

SPECTRUM1501134

Pimozide (JP17/USP/INN)

SPBio_001211

SPBio_002495

BPBio1_000304

SCHEMBL7519553

DTXSID8023474

BCBcMAP01_000043

HMS501D08

KBio1_000386

KBio2_000925

KBio2_003493

KBio2_006061

KBio3_002441

AOB5780

NINDS_000386

HMS1568N18

HMS1791H21

HMS1921H19

HMS1989H21

HMS2089C11

HMS2092F09

HMS2095N18

HMS2231P23

HMS3262N14

HMS3267E19

HMS3370N13

HMS3402H21

HMS3411J16

HMS3675J16

HMS3712N18

Pharmakon1600-01501134

ZINC4175630

Tox21_110224

Tox21_301586

Tox21_500946

BDBM50334150

CCG-35918

CCG-36461

CCG-39728

NSC757854

s4358

2-Benzimidazolinone, 1-1-4,4-bis(p-fluorophenyl)butyl-4-piperidyl-

3-1-4,4-bis(4-fluorophenyl)butyl-4-piperidyl-1H-benzimidazol-2-one

AKOS024458706

Tox21_110224_1

DB01100

LP00946

NSC-757854

SDCCGSBI-0050920.P004

IDI1_000386

SMP1_000241

NCGC00015802-01

NCGC00015802-02

NCGC00015802-03

NCGC00015802-04

NCGC00015802-05

NCGC00015802-06

NCGC00015802-07

NCGC00015802-09

NCGC00015802-10

NCGC00015802-11

NCGC00015802-12

NCGC00015802-13

NCGC00015802-14

NCGC00015802-15

NCGC00015802-16

NCGC00015802-26

NCGC00015802-29

NCGC00016601-01

NCGC00022282-03

NCGC00024888-01

NCGC00024888-02

NCGC00024888-03

NCGC00024888-04

NCGC00024888-05

NCGC00024888-06

NCGC00024888-07

NCGC00255294-01

NCGC00261631-01

AS-13916

HY-12987

M828

SBI-0050920.P003

AB00052215

CS-0012921

EU-0100946

FT-0673903

R-623

SW196639-3

C07566

D00560

AB00052215-06

AB00052215_07

AB00052215_08

062P784

117210-EP2272537A2

117210-EP2275420A1

117210-EP2295061A1

117210-EP2298776A1

L000494

Q144085

WLN: T56 BMVNJ D- DT6NTJ A3YR DF&R DF

J-013477

SR-01000075392-1

SR-01000075392-3

SR-01000075392-4

SR-01000075392-6

BRD-K01292756-001-06-0

BRD-K01292756-001-13-6

Pimozide, European Pharmacopoeia (EP) Reference Standard

Z241910386

2-Benzimidazolinone,4-bis(p-fluorophenyl)butyl-4-piperidyl-

N-benzyl-N-(3-isobutoxy-2-(pyrrolidin-1-yl)propyl)benzenamine

Pimozide, United States Pharmacopeia (USP) Reference Standard

1-1-4,4-Bis(p-flurophenyl)butyl-4-piperidyl-2-benzimidazolinone

1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)-1,3-dihydro-2H-benzodimidazol-2-one

1-{1-4,4-bis-(4-fluoro-phenyl)-butyl-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one

2H-Benzimidazol-2-one,4-bis(4-fluorophenyl)butyl-4-piperidinyl-1,3-dihydro-

1-{1-4,4-Bis-(4-fluoro-phenyl)-butyl-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Pimozide)

Pimozide (1-1-4,4-Bis(4-fluorophenyl)butyl-4-piperidinyl-1,3-dihydro-2H-benzimidaol-2-one)

PIMOZIDE1-{1-4,4-BIS-(4-FLUORO-PHENYL)-BUTYL-PIPERIDIN-4-YL}-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE
  Experimental Data
 pimozide

Species Dose Unit Control(Avg days) Treatment(Avg days) Avg/Med Lifespan Change(%) Control(Max days) Treatment(Max days) Max Lifespan Change(%) Significant Strain Gender PubMed Avg/Med Lifespan Change tab
Caenorhabditis elegans 100.000000000000000 umol/L 15.160000000000000 17.840000000000000 17.730000000000000 S N2 33008901 Active
Caenorhabditis elegans 10.000000000000000 umol/L 16.580000000000000 15.860000000000000 -4.343000000000000 NS N2 33008901 Inactive
Drosophila melanogaster 20.000000000000000 umol/L 46.240000000000000 48.620000000000000 5.149000000000000 NS FEMALES 33008901 Inactive
Drosophila melanogaster 200.000000000000000 umol/L 46.640000000000000 43.850000000000000 -5.975000000000000 NS MALES 33008901 Inactive
Caenorhabditis elegans 33.000000000000000 umol/L -32.000000000000000 NS N2 24134630 Inactive
  Experimental Data Visualization
 pimozide

  Statistics Data
 pimozide

Species Avg/Med Lifespan Change(%) Max Lifespan Change(%) Count Reference Count Data point
Caenorhabditis elegans 17.730000000000000 2 3
Drosophila melanogaster 5.149000000000000 1 2
  Statistics Data Visualization
 pimozide

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