Compound Summary

ofloxacin
  Compound Information
 ofloxacin

Compound Name:

ofloxacin

Compound CID:

4583

Synonyms:

ofloxacin

82419-36-1

Floxin

Ofloxacine

Tarivid

More...

Iupac Name:

7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid

InChI:

InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)

InChIKey:

GSDSWSVVBLHKDQ-UHFFFAOYSA-N

Canonical Smiles:

CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O

Isomeric Smiles:

CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O

Molecular Weight:

361.4

Molecular Formula:

C18H20FN3O4

  Compound Structure
 2D Structure:
 3D Structure:
  Computed Properties
 ofloxacin

Molecular Weight:

361.4

Molecular Formula:

C18H20FN3O4

Hydrogen Bond Donor Count:

1

Hydrogen Bond Acceptor Count:

8

Rotatable Bond Count:

2

Heavy Atom Count:

26

Complexity:

634

  Synonyms
 ofloxacin

ofloxacin ofloxacin

ofloxacin

82419-36-1

Floxin

Ofloxacine

Tarivid

Oxaldin

Ocuflox

Hoe-280

OFLX

Ofloxacino

Ofloxacinum

Exocin

DL-8280

Floxin otic

HOE 280

Dextrofloxacin

9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-1,4oxazino2,3,4-ijquinoline-6-carboxylic acid

9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-3,7-dihydro-2H-1,4oxazino2,3,4-ijquinoline-6-carboxylic acid

DL-ofloxacin

CHEBI:7731

Oflocet

Visiren

CHEMBL4

MFCD00226105

MLS000028749

Ofloxacina

Ofloxacin Otic

Ofloxacina DCIT

Ofloxacine French

Ofloxacinum Latin

Exocine

Flobacin

SMR000058192

Zanocin

Floxil

Ofloxacino Spanish

DSSTox_CID_21085

DSSTox_RID_79623

DSSTox_GSID_41085

8-Fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid

OFX

C18H20FN3O4

FLOXIN IN DEXTROSE 5%

DL 8280

MFCD00865049

PT 01

ORF 18489

(-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido1,2,3-de-1;(-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido1,2,3-de-1

9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido1,2,3-de-1,4-benzoxazine-6-carboxylic acid

Floxin (TN)

CCRIS 5233

(+/-)-Floxin

SR-01000076050

FLOXIN IN DEXTROSE 5% IN PLASTIC CONTAINER

BRN 3657947

Monoflocet

ofloxacin;

HSDB 8030

J01MA01

Ofloxacin,(S)

NCGC00016948-01

Ofloxacin (Floxin)

CAS-82419-36-1

DL8280

Exocin (eye drops)

Ofloxacin USAN:USP:INN:BAN:JAN

(+-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid

WP-0405

Spectrum_001186

(R)-Ofloxacin-d3

Opera_ID_1114

Prestwick0_000237

Prestwick1_000237

Prestwick2_000237

Prestwick3_000237

Spectrum2_001464

Spectrum3_001499

Spectrum4_000324

Spectrum5_001063

ACMC-20m40v

Epitope ID:116889

O 8757

Lopac0_000904

Oprea1_242882

SCHEMBL24373

BSPBio_000313

BSPBio_003117

KBioGR_000667

KBioSS_001666

83380-47-6

fluoro-methyl-(4-methylpiperazin-1-yl)-oxo-?carboxylic acid

MLS001074203

MLS006011774

DivK1c_000721

SPECTRUM1502044

SPBio_001387

SPBio_002234

(S)-Ofloxacin;Levaquin;Quixin

Ofloxacin (JP17/USP/INN)

BPBio1_000345

DTXSID3041085

SCHEMBL14163982

GTPL10918

HMS502E03

KBio1_000721

KBio2_001666

KBio2_004234

KBio2_006802

KBio3_002617

NINDS_000721

HMS1568P15

HMS1921H12

HMS2090F07

HMS2092B10

HMS2095P15

HMS2235C05

HMS3259G07

HMS3262F10

HMS3369B01

HMS3393K06

HMS3604B17

HMS3712P15

Pharmakon1600-01502044

7H-Pyrido1,2,3-de-1,4-benzoxazine-6-carboxylicacid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (3R)-

AMY22220

BCP14346

BCP22048

EBD13209

HY-B0125

RKL10083

Ofloxacin, fluoroquinolone antibiotic

Tox21_110703

Tox21_500904

BBL005605

BDBM50045004

CCG-39210

NSC727071

NSC758178

s1463

STK256723

AKOS001033517

AKOS016042783

Ofloxacine; DL-8280; HOE-280

Tox21_110703_1

AC-7616

BCP9000851

CS-1891

DB01165

KS-5011

LP00904

NC00466

NSC 727071

NSC 758178

NSC-727071

NSC-758178

SDCCGSBI-0050879.P004

VA11432

IDI1_000721

NCGC00015772-02

NCGC00015772-03

NCGC00015772-04

NCGC00015772-05

NCGC00015772-06

NCGC00015772-07

NCGC00015772-08

NCGC00015772-09

NCGC00015772-10

NCGC00015772-12

NCGC00015772-13

NCGC00015772-22

NCGC00094219-01

NCGC00094219-02

NCGC00094219-03

NCGC00094219-04

NCGC00094219-05

NCGC00094219-06

NCGC00178284-01

NCGC00178284-02

NCGC00261589-01

Ofloxacin 100 microg/mL in Acetonitrile

(+-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxazin-6-carbonsaeure

(+/-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido1,2,3-de-1,4-benzoxazine-6-carboxylic acid

7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 2,3-dihydro-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (+-)-

7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (+-)-

9-Fluoro-3,7-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2H-1,4oxazino2,3,4-ijquinoline-6-carboxylic Acid

H778

ST073364

SY007392

SBI-0050879.P003

AB0013254

DB-056608

AB00513820

EU-0100904

FT-0627808

FT-0630905

FT-0670773

FT-0673216

O0403

Ofloxacin, VETRANAL(TM), analytical standard

VU0243192-7

86O854

C07321

D00453

J10376

O-2800

AB00052263-12

AB00052263-13

AB00052263_14

AB00052263_15

Ofloxacin, Antibiotic for Culture Media Use Only

A864414

Q411447

SR-01000076050-1

SR-01000076050-4

SR-01000076050-7

BRD-A24228527-001-05-9

BRD-A24228527-001-19-0

SR-01000076050-16

Z56761309

F0020-0095

F0472-0226

138199-71-0 (0.5H2O)

7-Chloro-4-hydroxy-8-methylquinoline-3-carboxylicethylester

Ofloxacin, European Pharmacopoeia (EP) Reference Standard

Ofloxacin, United States Pharmacopeia (USP) Reference Standard

(+/-)-9-Fluoro-2,2,3-de)-1,4-benzoxazine-6-carboxylic acid

8-Methyl-2,3-dihydrofuro3,2-eimidazo-1,2-cpyrimidine-9-carboxylicacid

Ofloxacin, Pharmaceutical Secondary Standard; Certified Reference Material

()-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido1,2,3-de-1,4-benzoazine-6-carboxylic acid

(+/-)-9-Fluoro-2, 3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido1,2,3-de-1,4-benzoxazine-6-carboxylic acid

(3R)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-1,4oxazino2,3,4-ijquinoline-6-carboxylic acid

7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo7.3.1.0^{5,13}trideca-5(13),6,8,11-tetraene-11-carboxylic acid

7-Fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo7.3.1.05,13trideca-5,7,9(13),11-tetraene-11-carboxylic acid

7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-

9-Fluoro-10-(4-methylpiperazino)-3-methyl-7-oxo-2,3-dihydro-7H-pyrido1,2,3-de-1,4-benzooxazine-6-carboxylic acid

9-Fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido 1,2,3-de-1,4-Benzoxazin-6-carboxylic Acid

9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido1,2,3-de1,4benzoxazine-6-carboxylic acid

9-fluoro-3-methyl-10-(4-methylpiperazino)-7-oxo-2,3-dihydro-7H-1,4oxazino2,3,4-ijquinoline-6-carboxylic acid
  Experimental Data
 ofloxacin

Species Dose Unit Control(Avg days) Treatment(Avg days) Avg/Med Lifespan Change(%) Control(Max days) Treatment(Max days) Max Lifespan Change(%) Significant Strain Gender PubMed Avg/Med Lifespan Change tab
Caenorhabditis elegans 33.000000000000000 umol/L 8.000000000000000 NS N2 24134630 Inactive
  Experimental Data Visualization
 ofloxacin

  Statistics Data
 ofloxacin

Species Avg/Med Lifespan Change(%) Max Lifespan Change(%) Count Reference Count Data point
Caenorhabditis elegans 8.000000000000000 1 1
  Statistics Data Visualization
 ofloxacin

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