Compound Summary
o6-benzylguanine
Compound Information
o6-benzylguanine
Compound Name: | o6-benzylguanine |
Compound CID: | 4578 |
Synonyms: | o6-benzylguanine 6-O-Benzylguanine 19916-73-5 6-(Benzyloxy)-7H-purin-2-amine O(6)-Benzylguanine More... |
Iupac Name: | 6-phenylmethoxy-7H-purin-2-amine |
InChI: | InChI=1S/C12H11N5O/c13-12-16-10-9(14-7-15-10)11(17-12)18-6-8-4-2-1-3-5-8/h1-5,7H,6H2,(H3,13,14,15,16,17) |
InChIKey: | KRWMERLEINMZFT-UHFFFAOYSA-N |
Canonical Smiles: | C1=CC=C(C=C1)COC2=NC(=NC3=C2NC=N3)N |
Isomeric Smiles: | C1=CC=C(C=C1)COC2=NC(=NC3=C2NC=N3)N |
Molecular Weight: | 241.25 |
Molecular Formula: | C12H11N5O |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
o6-benzylguanine
Molecular Weight: | 241.25 |
Molecular Formula: | C12H11N5O |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 3 |
Heavy Atom Count: | 18 |
Complexity: | 271 |
Synonyms
o6-benzylguanine
| o6-benzylguanine | o6-benzylguanine |
|---|---|
o6-benzylguanine |
6-O-Benzylguanine |
19916-73-5 |
6-(Benzyloxy)-7H-purin-2-amine |
O(6)-Benzylguanine |
2-Amino-6-(benzyloxy)purine |
6-(benzyloxy)-9H-purin-2-amine |
2-amino-6-benzyloxypurine |
KRX-0402 |
6-Benzyloxyguanine |
1000874-21-4 |
6-(Phenylmethoxy)-1H-purin-2-amine |
2-Amino-6-(phenylmethoxy)-9H-purine |
6-phenylmethoxy-7H-purin-2-amine |
UNII-01KC87F8FE |
1H-Purin-2-amine, 6-(phenylmethoxy)- |
6-BENZYLGUANINE |
MFCD00269931 |
01KC87F8FE |
CHEMBL407874 |
6-(benzyloxy)-1H-purin-2-amine |
NSC637037 |
NSC-637037 |
O(6)-Bgua |
6-(Benzyloxy)guanine |
6-Benzyloxy guanine |
O6-BG |
SMR000326791 |
Purine, 2-amino-6-(benzyloxy)- |
916B735 |
NSC 637037 |
CCRIS 9383 |
6-benzyloxy-7H-purin-2-amine |
O6 -benzylguanine |
Purine, 8CI) |
9H-Purin-2-amine, 6-(phenylmethoxy)- |
Lopac-B-2292 |
O6-Benzylguanine- Bio-X |
6-benzyloxy-2-amino-purine |
Lopac0_000181 |
SCHEMBL61740 |
MLS000859930 |
MLS001074887 |
MLS006010145 |
6-benzyloxy-9H-purin-2-amine |
BDBM5491 |
2-Amino-6-benzyloxy-9H-purine |
0.4 CH3OH |
DTXSID20173700 |
6-(phenylmethoxy)purine-2-ylamine |
HMS2234P23 |
HMS3260F03 |
HMS3369A16 |
BCP08777 |
O6-Substituted Guanine Deriv. 31 |
ZINC5425464 |
6-(Benzyloxy)-7H-purin-2-ylamine |
Tox21_500181 |
s3658 |
SBB069180 |
AKOS015919415 |
AKOS015963409 |
AC-1076 |
CCG-204276 |
CS-W002585 |
DB11919 |
HY-W002585 |
KS-5281 |
LP00181 |
LS20601 |
SB17232 |
SDCCGSBI-0050169.P002 |
NCGC00015144-01 |
NCGC00015144-02 |
NCGC00015144-03 |
NCGC00015144-04 |
NCGC00015144-08 |
NCGC00093660-01 |
NCGC00093660-02 |
NCGC00260866-01 |
BB164163 |
H350 |
NCI60_012280 |
Purine, 2-amino-6-(benzyloxy)- (, ) |
SY008080 |
O6-Benzylguanine, >=98% (TLC), solid |
AB0013002 |
AM20060538 |
EU-0100181 |
FT-0650712 |
Y2972 |
B 2292 |
J10132 |
SR-01000075709 |
Q7072275 |
SR-01000075709-1 |
W-201741 |
OBG |
Experimental Data
o6-benzylguanine
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 100.000000000000000 | umol/L | 16.800000000000000 | 14.070000000000000 | -16.230000000000000 | NS | N2 | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 10.000000000000000 | umol/L | 16.590000000000000 | 16.370000000000000 | -1.355000000000000 | NS | N2 | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -9.000000000000000 | NS | N2 | 24134630 | Inactive | ||||||
| Drosophila melanogaster | 20.000000000000000 | umol/L | 54.370000000000000 | 53.460000000000000 | -1.670000000000000 | NS | FEMALES | 33008901 | Inactive | ||||
| Drosophila melanogaster | 200.000000000000000 | umol/L | 46.390000000000000 | 48.480000000000000 | 4.520000000000000 | NS | MALES | 33008901 | Inactive |
Experimental Data Visualization
o6-benzylguanine
Statistics Data
o6-benzylguanine
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -1.355000000000000 | 2 | 3 | |
| Drosophila melanogaster | 4.520000000000000 | 1 | 2 |
Statistics Data Visualization
o6-benzylguanine
