Compound Summary
niflumic acid
Compound Information
niflumic acid
Compound Name: | niflumic acid |
Compound CID: | 4488 |
Synonyms: | niflumic acid 4394-00-7 Nifluril Forenol Landruma More... |
Iupac Name: | 2-[3-(trifluoromethyl)anilino]pyridine-3-carboxylic acid |
InChI: | InChI=1S/C13H9F3N2O2/c14-13(15,16)8-3-1-4-9(7-8)18-11-10(12(19)20)5-2-6-17-11/h1-7H,(H,17,18)(H,19,20) |
InChIKey: | JZFPYUNJRRFVQU-UHFFFAOYSA-N |
Canonical Smiles: | C1=CC(=CC(=C1)NC2=C(C=CC=N2)C(=O)O)C(F)(F)F |
Isomeric Smiles: | C1=CC(=CC(=C1)NC2=C(C=CC=N2)C(=O)O)C(F)(F)F |
Molecular Weight: | 282.22 |
Molecular Formula: | C13H9F3N2O2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
niflumic acid
Molecular Weight: | 282.22 |
Molecular Formula: | C13H9F3N2O2 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 7 |
Rotatable Bond Count: | 3 |
Heavy Atom Count: | 20 |
Complexity: | 349 |
Synonyms
niflumic acid
| niflumic acid | niflumic acid |
|---|---|
niflumic acid |
4394-00-7 |
Nifluril |
Forenol |
Landruma |
Nifluminic acid |
Acido niflumico |
Acide niflumique |
2-{3-(trifluoromethyl)phenylamino}pyridine-3-carboxylic acid |
Acide niflumique INN-French |
Acido niflumico INN-Spanish |
Acidum niflumicum INN-Latin |
UP 83 |
2-3-(trifluoromethyl)anilinopyridine-3-carboxylic acid |
2-(3-(Trifluoromethyl)-phenyl)aminonicotinic acid |
2-(3-Trifluoromethylanilino)nicotinic Acid |
2-((3-(Trifluoromethyl)phenyl)amino)nicotinic acid |
2-(3-(Trifluoromethyl)anilino)nicotinic acid |
2-3-(Trifluoromethyl)anilinonicotinic acid |
2-{3-(TRIFLUOROMETHYL)PHENYLAMINO}NICOTINIC ACID |
Lopac-N-0630 |
UNII-4U5MP5IUD8 |
3-Pyridinecarboxylic acid, 2-3-(trifluoromethyl)phenylamino- |
2-(3-(Trifluoromethyl)phenylamino)nicotinic acid |
2-(alpha,alpha,alpha-Trifluoro-m-toluidino)nicotinic acid |
2-(3-TRIFLUOROMETHYL)PHENYLAMINO-3-PYRIDINE-CARBOXYLIC ACID |
4U5MP5IUD8 |
MLS000069713 |
NFL |
CHEBI:34888 |
3-Pyridinecarboxylic acid, 2-((3-(trifluoromethyl)phenyl)amino)- |
MFCD00010569 |
NCGC00015724-10 |
Niflumate |
SMR000058199 |
CAS-4394-00-7 |
DSSTox_CID_3368 |
2-(3-Trifluoromethylanilino)nicotinic acid |
Acidum niflumicum |
DSSTox_RID_76996 |
DSSTox_GSID_23368 |
Acide niflumique French |
Acido niflumico Italian |
Niflamol |
Niflugel (TN) |
SC 1332 |
CCRIS 5740 |
Niflumic acid (INN) |
SR-01000000231 |
EINECS 224-516-2 |
2-(3-Trifluoromethyl-phenylamino)-nicotinic acid |
BRN 0489360 |
2-3-(trifluoromethyl)phenylaminopyridine-3-carboxylic acid |
niflumic-acid |
ni-flumic acid |
Niflumic acid INN:BAN:DCF |
Actol, analgesic |
Aza-2 dimethyl-2,3 (tetrazolyl-5)-6 diphenylamino French |
Prestwick_890 |
Aza-2 dimethyl-2,3 (tetrazolyl-5)-6 diphenylamino |
Spectrum_001353 |
1td7 |
ACMC-209jvx |
Opera_ID_1746 |
Prestwick0_000255 |
Prestwick1_000255 |
Prestwick2_000255 |
Prestwick3_000255 |
Spectrum2_000794 |
Spectrum3_001485 |
Spectrum4_000043 |
Spectrum5_001216 |
Niflumic acid (Hit 16) |
N 0630 |
2-(3-Trifluoromethylphenyl)aminonicotinic Acid |
CBiol_001828 |
Lopac0_000845 |
SCHEMBL24706 |
BSPBio_000070 |
BSPBio_001393 |
BSPBio_003069 |
KBioGR_000113 |
KBioGR_000505 |
KBioSS_000113 |
KBioSS_001833 |
5-22-13-00598 (Beilstein Handbook Reference) |
MLS001076327 |
CHEMBL63323 |
DivK1c_000277 |
SPECTRUM1502015 |
SPBio_000928 |
SPBio_002289 |
BPBio1_000078 |
GTPL2439 |
DTXSID1023368 |
BDBM85507 |
HMS500N19 |
KBio1_000277 |
KBio2_000113 |
KBio2_001833 |
KBio2_002681 |
KBio2_004401 |
KBio2_005249 |
KBio2_006969 |
KBio3_000225 |
KBio3_000226 |
KBio3_002569 |
NINDS_000277 |
2-(3-Trifluoromethyl)phenylamino-3-pyridinecarboxylic Acid |
Bio1_000114 |
Bio1_000603 |
Bio1_001092 |
Bio2_000113 |
Bio2_000593 |
HMS1361F15 |
HMS1568D12 |
HMS1791F15 |
HMS1921D12 |
HMS1989F15 |
HMS2090D19 |
HMS2095D12 |
HMS2234F11 |
HMS3262J11 |
HMS3374H01 |
HMS3402F15 |
HMS3649A08 |
HMS3656P14 |
HMS3712D12 |
HMS3885I03 |
Nicotinic acid, 2-(alpha,alpha,alpha-trifluoro-m-toluidino)- |
Pharmakon1600-01502015 |
ZINC125031 |
HY-B0493 |
NSC_4488 |
Tox21_110206 |
Tox21_500845 |
BBL003619 |
CCG-40157 |
DL-457 |
Nicotinic acid, 2-(.alpha.,.alpha.,.alpha.-trifluoro-m-toluidino)- |
NSC758196 |
s3018 |
SBB001146 |
STK803109 |
AKOS000519590 |
Tox21_110206_1 |
AC-2652 |
DB04552 |
GS-3202 |
LP00845 |
MCULE-3027710274 |
NSC 758196 |
NSC-758196 |
SDCCGSBI-0050821.P004 |
IDI1_000277 |
IDI1_033863 |
NCGC00015724-01 |
NCGC00015724-02 |
NCGC00015724-03 |
NCGC00015724-04 |
NCGC00015724-05 |
NCGC00015724-06 |
NCGC00015724-07 |
NCGC00015724-08 |
NCGC00015724-09 |
NCGC00015724-11 |
NCGC00015724-12 |
NCGC00015724-13 |
NCGC00015724-14 |
NCGC00015724-17 |
NCGC00015724-29 |
NCGC00023636-03 |
NCGC00023636-04 |
NCGC00023636-05 |
NCGC00023636-06 |
NCGC00023636-07 |
NCGC00023636-08 |
NCGC00023636-09 |
NCGC00261530-01 |
ST013871 |
CAS_4394-00-7 |
SBI-0050821.P003 |
2(3-trifluormethylanilino)-nicotinic acid |
AB0012229 |
AB00052255 |
AM20070143 |
EU-0100845 |
FT-0603659 |
SW197011-3 |
T2353 |
A23222 |
D08275 |
H10042 |
S00109 |
AB00052255-17 |
AB00052255_18 |
AB00052255_19 |
394N007 |
Q304285 |
SR-01000000231-2 |
SR-01000000231-5 |
SR-01000000231-6 |
W-106215 |
BRD-K98763141-001-04-3 |
BRD-K98763141-001-06-8 |
BRD-K98763141-001-17-5 |
SR-01000000231-11 |
2-3-(Trifluoromethyl)anilino-3-pyridinecarboxylic acid |
Niflumic acid, European Pharmacopoeia (EP) Reference Standard |
Experimental Data
niflumic acid
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -13.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
niflumic acid
Statistics Data
niflumic acid
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -13.000000000000000 | 1 | 1 |
Statistics Data Visualization
niflumic acid
