Compound Summary
niclosamide
Compound Information
niclosamide
Compound Name: | niclosamide |
Compound CID: | 4477 |
Synonyms: | niclosamide 50-65-7 5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide Niclocide Bayluscid More... |
Iupac Name: | 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide |
InChI: | InChI=1S/C13H8Cl2N2O4/c14-7-1-4-12(18)9(5-7)13(19)16-11-3-2-8(17(20)21)6-10(11)15/h1-6,18H,(H,16,19) |
InChIKey: | RJMUSRYZPJIFPJ-UHFFFAOYSA-N |
Canonical Smiles: | C1=CC(=C(C=C1[N+](=O)[O-])Cl)NC(=O)C2=C(C=CC(=C2)Cl)O |
Isomeric Smiles: | C1=CC(=C(C=C1[N+](=O)[O-])Cl)NC(=O)C2=C(C=CC(=C2)Cl)O |
Molecular Weight: | 327.12 |
Molecular Formula: | C13H8Cl2N2O4 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
niclosamide
Molecular Weight: | 327.12 |
Molecular Formula: | C13H8Cl2N2O4 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 21 |
Complexity: | 404 |
Synonyms
niclosamide
| niclosamide | niclosamide |
|---|---|
niclosamide |
50-65-7 |
5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide |
Niclocide |
Bayluscid |
Phenasal |
Tredemine |
Fenasal |
Yomesan |
Dichlosale |
Helmiantin |
Atenase |
Cestocid |
Devermin |
Devermine |
Iomesan |
Iomezan |
Mansonil |
Radeverm |
Sagimid |
Vermitid |
Lintex |
Nasemo |
Sulqui |
2,5-Dichloro-4-nitrosalicylanilide |
Mato |
Fedal-Telmin |
Bayer 73 |
Zestocarp |
Bayer 2353 |
BAY 2353 |
Benzamide, 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxy- |
Chemagro 2353 |
C13H8Cl2N2O4 |
5-Chloro-2-chloro-4-nitrosalicylanilide |
nicolsamide |
HL 2447 |
WR 46234 |
Salicylanilide, 2,5-dichloro-4-nitro- |
UNII-8KK8CQ2K8G |
ENT 25823 |
2-Hydroxy-5-chloro-N-(2-chloro-4-nitrophenyl)benzamide |
N-(2-Chloro-4-nitrophenyl)-5-chlorosalicylamide |
2-Chloro-4-nitrophenylamide-6-chlorosalicylic acid |
2,5-Dichlor-4-nitro-salizylsaeureanilid" |
5-Chloro-N-(2-chloro-4-nitrophenyl)salicylamide |
8KK8CQ2K8G |
SR 73 |
Radewerm |
N-(2-Chlor-4-nitrophenyl)-5-chlorsalicylamid |
MFCD00057597 |
Niclosamide Anhydrous |
NSC-178296 |
CAS-50-65-7 |
NCGC00015735-07 |
DSSTox_CID_20362 |
DSSTox_RID_79485 |
DSSTox_GSID_40362 |
N-(2-Chloro-4-nitrophenyl)-5-chlorosalicylamide |
Niclosamida |
Niclosamidum |
Cestocide |
Niclosamidum INN-Latin |
Niclosamida INN-Spanish |
Nitrophenyl chlorsalicylamide |
Niclosamide USAN:INN:BAN |
CCRIS 3437 |
HSDB 1572 |
SR-01000076024 |
Niclosamide BSI:ISO |
EINECS 200-056-8 |
NSC 178296 |
BRN 2820605 |
Yomensan |
AI3-25823 |
5-Chlorosalicyloyl-(o-chloro-p-nitranilide) |
B 2353 |
Niclocide (TN) |
Prestwick_354 |
2,5-Dichlor-4-nitro-salizylsaeureanilid German |
Mollutox (Salt/Mix) |
N-(2-Chlor-4-nitrophenyl)-5-chlorsalicylamid German |
Spectrum_000239 |
Niclosamide (Niclocide) |
Clonitralid (Salt/Mix) |
Clonitralide (Salt/Mix) |
Prestwick0_000040 |
Prestwick1_000040 |
Prestwick2_000040 |
Prestwick3_000040 |
Spectrum2_001183 |
Spectrum3_000667 |
Spectrum4_000196 |
Spectrum5_001083 |
Lopac-N-3510 |
Niclosamide (USAN/INN) |
CHEMBL1448 |
Lopac0_000866 |
Oprea1_259151 |
SCHEMBL67182 |
BSPBio_000139 |
BSPBio_002333 |
KBioGR_000771 |
KBioSS_000719 |
MLS002154181 |
DivK1c_000709 |
SPECTRUM1503265 |
SPBio_001225 |
SPBio_002060 |
BPBio1_000153 |
CHEBI:7553 |
GTPL8494 |
DTXSID7040362 |
SCHEMBL18563900 |
WLN: WNR CG DMVR BQ EG |
BDBM11242 |
HMS502D11 |
KBio1_000709 |
KBio2_000719 |
KBio2_003287 |
KBio2_005855 |
KBio3_001553 |
5-Chloro-N-(2-chloro-4-nitro-phenyl)-2-hydroxy-benzamide |
Niclosamide - CAS 50-65-7 |
NINDS_000709 |
HMS1568G21 |
HMS2093A21 |
HMS2095G21 |
HMS2231H06 |
HMS3262N13 |
HMS3373P08 |
HMS3712G21 |
KUC107299N |
Pharmakon1600-01503265 |
BAY-2353 |
BCP22958 |
HY-B0497 |
ZINC3874496 |
Tox21_110209 |
Tox21_300749 |
Tox21_500866 |
BBL004110 |
CCG-39641 |
NSC178296 |
NSC758440 |
s3030 |
Salicylanilide,5-dichloro-4-nitro- |
STK396676 |
2,5-dichloro-4-nitrosalicylanilide ? |
AKOS003589004 |
Tox21_110209_1 |
AT15436 |
BCP9000068 |
DB06803 |
KS-5210 |
LP00866 |
MCULE-9985514311 |
NSC-758440 |
SB19414 |
SDCCGSBI-0050841.P004 |
2,5-Dichloro-4-nitrosalicylanilide |
IDI1_000709 |
SMP2_000228 |
5-chloro-N-(2-chloro-4-nitrophenyl)- |
NCGC00015735-01 |
NCGC00015735-02 |
NCGC00015735-03 |
NCGC00015735-04 |
NCGC00015735-05 |
NCGC00015735-06 |
NCGC00015735-08 |
NCGC00015735-09 |
NCGC00015735-11 |
NCGC00015735-12 |
NCGC00015735-24 |
NCGC00094190-01 |
NCGC00094190-02 |
NCGC00094190-03 |
NCGC00094190-04 |
NCGC00254654-01 |
NCGC00261551-01 |
I012 |
KSC-18-157-2 |
SMR000058390 |
Niclosamide 100 microg/mL in Acetonitrile |
SBI-0050841.P003 |
AB0013423 |
DB-051812 |
VU0243604 |
AB00052340 |
EU-0100866 |
FT-0603220 |
ST50408862 |
EN300-92958 |
D00436 |
N 3510 |
AB00052340_08 |
AB00052340_09 |
A828227 |
Q418523 |
Q-201469 |
SR-01000076024-1 |
SR-01000076024-3 |
SR-01000076024-6 |
BRD-K35960502-001-06-9 |
BRD-K35960502-001-11-9 |
Z57902203 |
5-Chloro-N-(2-chloro-4-nitrophenyl) -2-hydroxybenzamide |
5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxy-benzamide |
(5-chloro-2-hydroxyphenyl)-N-(2-chloro-4-nitrophenyl)carboxamide |
5-chloranyl-N-(2-chloranyl-4-nitro-phenyl)-2-oxidanyl-benzamide |
Niclosamide (anhydrous), European Pharmacopoeia (EP) Reference Standard |
Experimental Data
niclosamide
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -21.000000000000000 | NS | N2 | 24134630 | Inactive | ||||||
| Drosophila melanogaster | 20.000000000000000 | umol/L | 45.440000000000000 | 42.060000000000000 | -7.448000000000000 | NS | FEMALES | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 100.000000000000000 | umol/L | 17.400000000000000 | 17.420000000000000 | 0.103400000000000 | NS | N2 | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 10.000000000000000 | umol/L | 15.130000000000000 | 14.960000000000000 | -1.123000000000000 | NS | N2 | 33008901 | Inactive | ||||
| Drosophila melanogaster | 200.000000000000000 | umol/L | 44.800000000000000 | 48.360000000000000 | 7.945000000000000 | NS | MALES | 33008901 | Inactive |
Experimental Data Visualization
niclosamide
Statistics Data
niclosamide
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 0.103400000000000 | 2 | 3 | |
| Drosophila melanogaster | 7.945000000000000 | 1 | 2 |
Statistics Data Visualization
niclosamide
