Compound Summary
mizoribine
Compound Information
mizoribine
Compound Name: | mizoribine |
Compound CID: | 104762 |
Synonyms: | mizoribine 50924-49-7 Bredinin HE-69 UNII-4JR41A10VP More... |
Iupac Name: | 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-hydroxyimidazole-4-carboxamide |
InChI: | InChI=1S/C9H13N3O6/c10-7(16)4-8(17)12(2-11-4)9-6(15)5(14)3(1-13)18-9/h2-3,5-6,9,13-15,17H,1H2,(H2,10,16)/t3-,5-,6-,9-/m1/s1 |
InChIKey: | HZQDCMWJEBCWBR-UUOKFMHZSA-N |
Canonical Smiles: | C1=NC(=C(N1C2C(C(C(O2)CO)O)O)O)C(=O)N |
Isomeric Smiles: | C1=NC(=C(N1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)O)C(=O)N |
Molecular Weight: | 259.22 |
Molecular Formula: | C9H13N3O6 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
mizoribine
Molecular Weight: | 259.22 |
Molecular Formula: | C9H13N3O6 |
Hydrogen Bond Donor Count: | 5 |
Hydrogen Bond Acceptor Count: | 7 |
Rotatable Bond Count: | 3 |
Heavy Atom Count: | 18 |
Complexity: | 329 |
Synonyms
mizoribine
| mizoribine | mizoribine |
|---|---|
mizoribine |
50924-49-7 |
Bredinin |
HE-69 |
UNII-4JR41A10VP |
MLS000028813 |
1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-hydroxy-1H-imidazole-4-carboxamide |
HE 69 |
5-Hydroxy-1-beta-D-ribofuranosyl-1H-imidazole-4-carboxamide |
1H-Imidazole-4-carboxamide, 5-hydroxy-1-beta-D-ribofuranosyl- |
SMR000058473 |
5-Hydroxy-1-beta-D-ribofuranosylimidazole-4-carboxamide |
1-(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl-5-hydroxyimidazole-4-carboxamide |
4JR41A10VP |
Bredinine |
MFCD00057221 |
NSC 289637 |
50524-49-7 |
NCGC00094087-01 |
Mizoribinum |
Mizoribina |
Mizoribine INN:JAN |
DSSTox_CID_25777 |
DSSTox_RID_81119 |
DSSTox_GSID_45777 |
Mizoribinum INN-Latin |
Mizoribina INN-Spanish |
Bredinin (TN) |
1-(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl-5-hydroxy-1H-imidazole-4-carboxamide |
CAS-50924-49-7 |
SR-01000075989 |
BRN 4151713 |
4-Carbamoyl-1-beta-D-ribofuranosyl-imidazolium-5-olate |
Anhydro-4-carbamoyl-5-hydroxy-1-beta-D-ribofuranosyl-imidazolium hydroxide |
Mizoribine(Bredinin) |
HS-0046 |
Mizoribine (Bredinin) |
Opera_ID_1558 |
Spectrum2_001559 |
Spectrum3_000739 |
Spectrum4_000220 |
Spectrum5_001671 |
Mizoribine (JP17/INN) |
M 3047 |
SCHEMBL7118 |
Lopac0_000745 |
BSPBio_002298 |
KBioGR_000859 |
MLS001076272 |
MLS006010038 |
DivK1c_000948 |
SPBio_001438 |
CHEMBL245019 |
cid_104762 |
Mizoribine, >=98% (TLC) |
DTXSID8045777 |
BDBM68669 |
CHEBI:31858 |
HMS502P10 |
KBio1_000948 |
KBio3_001518 |
N-(beta-D-Ribofuranosyl)-5-hydroxyimidazole-4-carboxamide |
NINDS_000948 |
HMS2230D04 |
HMS3262E12 |
N-(beta-D-Ribofuranosyl)-5-hydroxy-imida-zole-4-carboxamide |
EX-A2256 |
ZINC3812887 |
Tox21_111242 |
Tox21_500745 |
CCG-39778 |
FD9057 |
QC-367 |
s1384 |
AKOS015994615 |
Tox21_111242_1 |
AC-5266 |
BCP9000933 |
CS-1823 |
DB12617 |
LP00745 |
SDCCGSBI-0050723.P004 |
IDI1_000948 |
SMP1_000195 |
NCGC00094087-02 |
NCGC00094087-03 |
NCGC00094087-04 |
NCGC00094087-05 |
NCGC00261430-01 |
HY-17470 |
Q571 |
BCP0726000318 |
SBI-0050723.P003 |
AB0017672 |
EU-0100745 |
M2399 |
A16794 |
D01392 |
AB00053323_12 |
AB00053323_13 |
924M497 |
J-700185 |
Q6884708 |
SR-01000075989-1 |
SR-01000075989-4 |
1-(beta-D-Ribofuranosyl)-5-hydroxyimidazole-4-carboxamide |
4-Carbamoyl-1-(beta-D-ribofuranosyl)-5-oxylatoimidazolium |
5-hydroxy-1-b-D-ribofuranosyl-1H-Imidazole-4-carboxamide |
1H-Imidazole-4-carboxamide, 5-hydroxy-1-b-D-ribofuranosyl- |
1-(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-2-oxolanyl-5-hydroxy-4-imidazolecarboxamide |
1-(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl-5-hydroxy-imidazole-4-carboxamide |
1-(2R,3R,4S,5R)-3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl-5-hydroxy-imidazole-4-carboxamide |
1-(2R,3R,4S,5R)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl-5-oxidanyl-imidazole-4-carboxamide |
Bredinin|||HE-69|||NSC-289637|||1-(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl-5-hydroxyimidazole-4-carboxamide |
Experimental Data
mizoribine
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -1.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
mizoribine
Statistics Data
mizoribine
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -1.000000000000000 | 1 | 1 |
Statistics Data Visualization
mizoribine
