Compound Summary

loratadine
  Compound Information
 loratadine

Compound Name:

loratadine

Compound CID:

3957

Synonyms:

loratadine

79794-75-5

Claritin

Loratidine

Alavert

More...

Iupac Name:

ethyl 4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylate

InChI:

InChI=1S/C22H23ClN2O2/c1-2-27-22(26)25-12-9-15(10-13-25)20-19-8-7-18(23)14-17(19)6-5-16-4-3-11-24-21(16)20/h3-4,7-8,11,14H,2,5-6,9-10,12-13H2,1H3

InChIKey:

JCCNYMKQOSZNPW-UHFFFAOYSA-N

Canonical Smiles:

CCOC(=O)N1CCC(=C2C3=C(CCC4=C2N=CC=C4)C=C(C=C3)Cl)CC1

Isomeric Smiles:

CCOC(=O)N1CCC(=C2C3=C(CCC4=C2N=CC=C4)C=C(C=C3)Cl)CC1

Molecular Weight:

382.9

Molecular Formula:

C22H23ClN2O2

  Compound Structure
 2D Structure:
 3D Structure:
  Computed Properties
 loratadine

Molecular Weight:

382.9

Molecular Formula:

C22H23ClN2O2

Hydrogen Bond Donor Count:

0

Hydrogen Bond Acceptor Count:

3

Rotatable Bond Count:

2

Heavy Atom Count:

27

Complexity:

569

  Synonyms
 loratadine

loratadine loratadine

loratadine

79794-75-5

Claritin

Loratidine

Alavert

Clarityn

Lisino

Clarityne

Loracert

Loradex

Bonalerg

Claritine

Fristamin

Histaloran

Lertamine

Lorastine

Civeran

Loranox

Versal

Sch 29851

Anhissen

Sch-29851

UNII-7AJO3BO7QN

ethyl 4-(8-chloro-5,6-dihydro-11H-benzo5,6cyclohepta1,2-bpyridin-11-ylidene)piperidine-1-carboxylate

MFCD00672869

C22H23ClN2O2

Loratyne

Allertidin

Claratyne

Polaratyne

Restamine

Aerotina

Alerpriv

Biloina

Lesidas

Loradif

Lorantis

Loraver

Lorfast

Loritine

Lowadina

Nularef

Optimin

Sanelor

Sensibit

Sohotin

Velodan

7AJO3BO7QN

Lergy

Pylor

Tadine

Ethyl 4-(8-chloro-5,6-dihydro-11H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-ylidene)-1-piperidinecarboxylate

CHEMBL998

Zeos

Sinhistan Dy

Bedix Loratadina

Talorat Dy

Claritin Reditabs

Clarinase Reperabs

MLS000069647

ethyl 4-{13-chloro-4-azatricyclo9.4.0.0^{3,8}pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene}piperidine-1-carboxylate

Loratadinum Latin

Claritin reditab

Loratadina Spanish

Clarityne-D

1-Piperidinecarboxylic acid, 4-(8-chloro-5,6-dihydro-11H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-ylidene)-, ethyl ester

1-Piperidinecarboxylic acid, 4-(8-chloro-5,6-dihydro-11H-benzo5,6cyclohepta1,2-bpyridin-11-ylidene)-, ethyl ester

ethyl 4-(8-chloro-5,6-dihydrobenzo1,2cyclohepta2,4-bpyridin-11-ylidene)piperidine-1-carboxylate

Childrens Claritin

NCGC00015619-09

Loratadinum

Loratadina

SMR000058255

Clarityne Dy Repetabs

DSSTox_CID_3224

DSSTox_RID_76931

DSSTox_GSID_23224

Loratadine Redidose

Ethyl 4-(8-chloro-5,6-dihydro-11H-benzo5,6cyclohepta1,2-bpyridin-11-ylidene)-1-piperidinecarboxylate

Claritin Hives Relief

Bactimicina allergy

Claritin (TN)

Claritin Hives Relief Reditab

CAS-79794-75-5

HSDB 3578

SR-01000075968

Cronopen

Flonidan

Klaritin

loratadine-form1

Topcare childrens allergy relief

LoratadineI-p25

Loratadine,(S)

Loratadine USAN:USP:INN:BAN

Loratadine- Bio-X

loratadine-form2-He

1398065-63-8

Spectrum_001496

Tocris-1944

LoratadineI-0deg(L13)

Opera_ID_1868

Spectrum2_001584

Spectrum3_000740

Spectrum4_000177

Spectrum5_001650

Lopac-L-9664

Loratadine-d5(ethyl-d5)

LoratadineI-p80(L13)

L 9664

LoratadineI-m100(L13)

LoratadineI-m173(L13)

SCHEMBL4596

Lopac0_000680

Oprea1_027965

REGID_for_CID_3957

BSPBio_002300

KBioGR_000693

KBioSS_001976

Loratadine (JAN/USP/INN)

MLS000758260

MLS001148466

MLS001423984

BIDD:GT0198

DivK1c_000792

SPECTRUM1503712

SPBio_001548

CHEBI:6538

GTPL7216

DTXSID2023224

BDBM22876

HMS502H14

KBio1_000792

KBio2_001976

KBio2_004544

KBio2_007112

KBio3_001520

NINDS_000792

HMS2051G11

HMS2090O18

HMS2093I15

HMS2235G23

HMS3262G21

HMS3268M16

HMS3371D13

HMS3393G11

HMS3412N06

HMS3654L17

HMS3676N06

HMS3714E09

Pharmakon1600-01503712

ZINC537931

Loratadine 0.1 mg/ml in Methanol

ACT04775

AMY15355

BCP22338

Tox21_110185

Tox21_301532

Tox21_500680

BBL010757

CCG-39362

CL0028

DL-436

HTS028367

NSC721075

NSC758628

s1358

STK574925

AKOS005499513

Loratadine (Desloratadine Impurity E)

Loratadine, >=98% (HPLC), powder

Tox21_110185_1

AB06849

AC-2086

BAY76-2211

BCP9000858

CCG-100786

CS-0887

DB00455

KS-1079

LP00680

MCULE-5073177964

NC00036

NSC 721075

NSC 758628

NSC-721075

NSC-758628

SDCCGSBI-0050659.P004

IDI1_000792

NCGC00015619-01

NCGC00015619-02

NCGC00015619-03

NCGC00015619-04

NCGC00015619-05

NCGC00015619-06

NCGC00015619-07

NCGC00015619-08

NCGC00015619-10

NCGC00015619-11

NCGC00015619-12

NCGC00015619-13

NCGC00015619-26

NCGC00023125-02

NCGC00023125-04

NCGC00023125-05

NCGC00023125-06

NCGC00023125-07

NCGC00255171-01

NCGC00261365-01

4-(8-chloro-5,6-dihydro-11H-benzo5,6cycloheptal1,2-bpyridin-11-ylidene-1-piperidinecarboxylic acid ethyl ester

BL164637

ethyl 4-(13-chloro-4-azatricyclo9.4.0.03,8pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylate

HY-17043

NCI60_041473

SY052751

BCP0726000007

SBI-0050659.P003

AB0012486

EU-0100680

FT-0627976

L0223

SW197416-3

D00364

J10034

AB00053224-15

AB00053224-16

AB00053224_17

AB00053224_18

794L755

L000667

Q424049

Q-100833

SR-01000075968-1

SR-01000075968-3

SR-01000075968-4

SR-01000075968-6

BRD-K82795137-001-02-3

BRD-K82795137-001-10-6

Z1741979837

Loratadine, British Pharmacopoeia (BP) Reference Standard

Loratadine, European Pharmacopoeia (EP) Reference Standard

Loratadine, United States Pharmacopeia (USP) Reference Standard

Loratadine, Pharmaceutical Secondary Standard; Certified Reference Material

Loratadine for system suitability, European Pharmacopoeia (EP) Reference Standard

1-Piperidenecarboxylic acid,6-duhydro-11H-benzo 5,6cyclohepta1,2-b-pyridin-11-ylidene)-, ethyl ester

1-Piperidinecarboxylic acid,4-(8-chloro-5,6-dihydro-11H-benzo5,6cyclohepta1,2-bpyridin-11-ylidene)-, ethyl ester

11-N-(ethoxycarbonyl)-4-piperidylidene-8-chloro-6,11-dihydro-5H-benzo-5,6cyclohepta1,2-bpyridine

4-(8-chloro-5,6-dihydro-11H-benzo5,6cyclohepta1,2-bpyridin-11-ylidene)-1-piperidinecarboxylic acid ethyl ester

4-(8-Chloro-5,6-dihydro-11H-benzo5,6cyclohepta1,2-bpyridin-11-ylidene-1-piperidinecarboxylic acid ethyl ester

4-(8-Chloro-5,6-dihydro-benzo5,6cyclohepta1,2-bpyridin-11-ylidene)-piperidine-1-carboxylic acid ethyl ester

4-(8-chloro-5,6-dihydrobenzo5,6cyclohepta1,2-bpyridin-11-ylidene)piperidine-1-carboxylic acid ethyl ester

8-chloro-11-(1-ethoxycarbonyl-4-piperidylidene)-6,11-dihydro-5H-benzo5,6cyclohepta1,2-bpyridine

8-chloro-6,11-dihydro-11-(1- ethoxycarbonyl-4-piperidylidene)-5H-benzo5,6cyclohepta1,2-bpyridine

8-Chloro-6,11-dihydro-11-(1-ethoxycarbonyl-4-piperidylidene)-5H-benzo5,6cyclohepta1,2-bpyridine

Ethyl 4-(8-chloro-5,6-dihydro-11H-benzo5,6cyclohepta1,2-bpyridin-11-ylidine)-1-piperidinecarboxylate

Ethyl-4-(8-chloro-5,6-dihydro-11H-benzo 5,6 cyclohepta 1,2-bpyridin-11-ylidene)-1-piperidinecarboxylate

loratadine impurity c;4-(4,8-dichloro-5,6-dihydro-11h-benzo(5,6)cyclohepta(1,2-b)pyridin-11-ylidene)-1-piperidinecarboxylic acid ethyl ester
  Experimental Data
 loratadine

Species Dose Unit Control(Avg days) Treatment(Avg days) Avg/Med Lifespan Change(%) Control(Max days) Treatment(Max days) Max Lifespan Change(%) Significant Strain Gender PubMed Avg/Med Lifespan Change tab
Caenorhabditis elegans 33.000000000000000 umol/L 18.000000000000000 S N2 24134630 Active
Caenorhabditis elegans 33.000000000000000 umol/L 18.000000000000000 S N2 33683565 Active
  Experimental Data Visualization
 loratadine

  Statistics Data
 loratadine

Species Avg/Med Lifespan Change(%) Max Lifespan Change(%) Count Reference Count Data point
Caenorhabditis elegans 18.000000000000000 2 2
  Statistics Data Visualization
 loratadine

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