Compound Summary
lonidamine
Compound Information
lonidamine
Compound Name: | lonidamine |
Compound CID: | 39562 |
Synonyms: | lonidamine 50264-69-2 1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylic acid Diclondazolic acid Doridamina More... |
Iupac Name: | 1-[(2,4-dichlorophenyl)methyl]indazole-3-carboxylic acid |
InChI: | InChI=1S/C15H10Cl2N2O2/c16-10-6-5-9(12(17)7-10)8-19-13-4-2-1-3-11(13)14(18-19)15(20)21/h1-7H,8H2,(H,20,21) |
InChIKey: | WDRYRZXSPDWGEB-UHFFFAOYSA-N |
Canonical Smiles: | C1=CC=C2C(=C1)C(=NN2CC3=C(C=C(C=C3)Cl)Cl)C(=O)O |
Isomeric Smiles: | C1=CC=C2C(=C1)C(=NN2CC3=C(C=C(C=C3)Cl)Cl)C(=O)O |
Molecular Weight: | 321.2 |
Molecular Formula: | C15H10Cl2N2O2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
lonidamine
Molecular Weight: | 321.2 |
Molecular Formula: | C15H10Cl2N2O2 |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 3 |
Heavy Atom Count: | 21 |
Complexity: | 396 |
Synonyms
lonidamine
| lonidamine | lonidamine |
|---|---|
lonidamine |
50264-69-2 |
1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylic acid |
Diclondazolic acid |
Doridamina |
DICA |
Lonidamina |
Lonidaminum |
Lonidamin |
1-(2,4-dichlorophenyl)methyl-1H-indazole-3-carboxylic acid |
AF 1890 |
1-(2,4-Dichlorbenzyl)-indazole-3-carboxylic acid |
UNII-U78804BIDR |
1-(2,4-dichlorophenyl)methylindazole-3-carboxylic acid |
C15H10Cl2N2O2 |
1-(2,4-dichlorobenzyl)indazole-3-carboxylic acid |
AF-1890 |
MLS000028822 |
U78804BIDR |
CHEBI:50138 |
1H-Indazole-3-carboxylic acid, 1-(2,4-dichlorophenyl)methyl- |
AF-1890;Diclondazolic Acid;DICA |
MFCD00866285 |
NCGC00015609-03 |
SMR000058467 |
DSSTox_CID_782 |
DSSTox_RID_75787 |
DSSTox_GSID_20782 |
Lonidaminum INN-Latin |
Lonidamina INN-Spanish |
Doridamina (TN) |
Dichlondazolic acid |
Lonidamine (INN) |
CAS-50264-69-2 |
CCRIS 3516 |
Lonidamine INN:BAN |
SR-01000075961 |
EINECS 256-510-0 |
BRN 0894483 |
KN-228 |
TH-070 |
Tocris-1646 |
Lopac-L-4900 |
L 4900 |
SCHEMBL7134 |
Lopac0_000718 |
cid_39562 |
ZINC1632 |
CHEMBL1257030 |
DTXSID5020782 |
BDBM59775 |
1H-Indazole-3-carboxylic acid, 1-(2,4-dichlorobenzyl)- |
HMS2234H24 |
HMS3262O17 |
HMS3268K09 |
HMS3369I01 |
HMS3412P05 |
HMS3651F09 |
HMS3676P05 |
HMS3874D03 |
Pharmakon1600-01503225 |
1H-Indazole-3-carboxylicacid, 1-(2,4-dichlorophenyl)methyl- |
ACT02617 |
BCP06555 |
HY-B0486 |
Tox21_110181 |
Tox21_202306 |
Tox21_500718 |
AF1890 |
NSC741419 |
NSC758419 |
s2610 |
AKOS012842739 |
Tox21_110181_1 |
AC-5626 |
CCG-204803 |
DB06266 |
LP00718 |
NSC 741419 |
NSC 758419 |
NSC-741419 |
NSC-758419 |
SDCCGSBI-0050696.P003 |
NCGC00015609-01 |
NCGC00015609-02 |
NCGC00015609-04 |
NCGC00015609-05 |
NCGC00015609-06 |
NCGC00015609-07 |
NCGC00015609-08 |
NCGC00015609-09 |
NCGC00015609-16 |
NCGC00025244-01 |
NCGC00025244-02 |
NCGC00025244-03 |
NCGC00259855-01 |
NCGC00261403-01 |
AS-11653 |
SBI-0050696.P002 |
AB0010495 |
AM20060642 |
EU-0100718 |
FT-0650359 |
SW219810-1 |
Lonidamine, mitochondrial hexokinase inhibitor |
D07257 |
J90044 |
AB00597141_08 |
AB00597141_10 |
264L692 |
A929099 |
Q-201318 |
Q3836670 |
SR-01000075961-1 |
SR-01000075961-3 |
SR-01000075961-6 |
BRD-K78513633-001-03-3 |
BRD-K78513633-001-06-6 |
Z1741977188 |
1-(2,4-dichlorophenyl)methyl-3-indazolecarboxylic acid |
1-(2,4-Dichlorophenyl)Methyl-1H-indazole-3-carboxylicacid |
1H-Indazole-3-carboxylic acid, 1-((2,4-dichlorophenyl)methyl)- (9CI) |
Experimental Data
lonidamine
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 5.000000000000000 | umol/L | 7.940000000000000 | Unclear | N2 | 33683565 | |||||||
| Caenorhabditis elegans | 5.000000000000000 | umol/L | Unclear | N2 | 33683565 | ||||||||
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -3.000000000000000 | NS | N2 | 24134630 | Inactive | ||||||
| Caenorhabditis elegans | 5.000000000000000 | % | 23.500000000000000 | 34.000000000000000 | 0.450000000000000 | S | N2 | 21932172 | Active |
Experimental Data Visualization
lonidamine
Statistics Data
lonidamine
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 0.450000000000000 | 7.940000000000000 | 3 | 4 |
Statistics Data Visualization
lonidamine
