Compound Summary
ic261
Compound Information
ic261
Compound Name: | ic261 |
Compound CID: | 5288600 |
Synonyms: | ic261 IC 261 186611-52-9 3-(2,4,6-TRIMETHOXY-PHENYL)-METHYLENE-INDOLIN-2-ONE SU-5607 More... |
Iupac Name: | (3E)-3-[(2,4,6-trimethoxyphenyl)methylidene]-1H-indol-2-one |
InChI: | InChI=1S/C18H17NO4/c1-21-11-8-16(22-2)14(17(9-11)23-3)10-13-12-6-4-5-7-15(12)19-18(13)20/h4-10H,1-3H3,(H,19,20)/b13-10+ |
InChIKey: | JBJYTZXCZDNOJW-JLHYYAGUSA-N |
Canonical Smiles: | COC1=CC(=C(C(=C1)OC)C=C2C3=CC=CC=C3NC2=O)OC |
Isomeric Smiles: | COC1=CC(=C(C(=C1)OC)/C=C/2\C3=CC=CC=C3NC2=O)OC |
Molecular Weight: | 311.3 |
Molecular Formula: | C18H17NO4 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
ic261
Molecular Weight: | 311.3 |
Molecular Formula: | C18H17NO4 |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 23 |
Complexity: | 450 |
Synonyms
ic261
| ic261 | ic261 |
|---|---|
ic261 |
IC 261 |
186611-52-9 |
3-(2,4,6-TRIMETHOXY-PHENYL)-METHYLENE-INDOLIN-2-ONE |
SU-5607 |
(3E)-3-(2,4,6-trimethoxyphenyl)methylidene-1H-indol-2-one |
3-(2,4,6-Trimethoxyphenyl)methylidenyl-indolin-2-one |
SU5607 |
CHEMBL489156 |
MFCD00118156 |
(E)-3-(2,4,6-trimethoxybenzylidene)indolin-2-one |
IC1 |
1,3-Dihydro-3-(2,4,6-trimethoxyphenyl)methylene-2H-indol-2-one |
Lopac-I-0658 |
3-(2,4,6-trimethoxybenzylidene)indolin-2-one |
Lopac0_001017 |
SCHEMBL2786157 |
3-((2,4,6-trimethoxyphenyl)methylidenyl)indolin-2-one |
HMS1433C06 |
HMS3229I10 |
HMS3263K15 |
ZINC136945 |
EX-A4178 |
Tox21_501017 |
BDBM50263829 |
HSCI1_000024 |
s8237 |
CCG-205097 |
CS-4967 |
DB03083 |
LP01017 |
SDCCGSBI-0050990.P003 |
SU 5607 |
SU5607 (IC261) |
IDI1_012141 |
NCGC00015546-01 |
NCGC00015546-02 |
NCGC00015546-03 |
NCGC00015546-04 |
NCGC00094309-01 |
NCGC00094309-02 |
NCGC00261702-01 |
AS-55870 |
HY-12774 |
EU-0101017 |
I 0658 |
SR-01000075566 |
IC261 - CAS 186611-52-9 |
J-011989 |
SR-01000075566-1 |
BRD-K09638361-001-01-4 |
Q27461368 |
(3E)-3-(2,4,6-trimethoxyphenyl)methylidene-1,3-dihydro-2H-indol-2-one |
Experimental Data
ic261
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | 11.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
ic261
Statistics Data
ic261
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 11.000000000000000 | 1 | 1 |
Statistics Data Visualization
ic261
