Compound Summary

hydrocortisone
  Compound Information
 hydrocortisone

Compound Name:

hydrocortisone

Compound CID:

5754

Synonyms:

hydrocortisone

Cortisol

50-23-7

Acticort

Cetacort

More...

Iupac Name:

(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one

InChI:

InChI=1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1

InChIKey:

JYGXADMDTFJGBT-VWUMJDOOSA-N

Canonical Smiles:

CC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4(C(=O)CO)O)C)O

Isomeric Smiles:

C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@]4(C(=O)CO)O)C)O

Molecular Weight:

362.5

Molecular Formula:

C21H30O5

  Compound Structure
 2D Structure:
 3D Structure:
  Computed Properties
 hydrocortisone

Molecular Weight:

362.5

Molecular Formula:

C21H30O5

Hydrogen Bond Donor Count:

3

Hydrogen Bond Acceptor Count:

5

Rotatable Bond Count:

2

Heavy Atom Count:

26

Complexity:

684

  Synonyms
 hydrocortisone

hydrocortisone hydrocortisone

hydrocortisone

Cortisol

50-23-7

Acticort

Cetacort

Hydrasson

Hydrocortisyl

Cobadex

Hydrocortone

Cortef

Hycort

Hytone

Signef

17-Hydroxycorticosterone

Optef

Kendalls compound F

Cortanal

Cortenema

Corticreme

Cortifan

Cortiment

Cortispray

Cortonema

Dermacort

Dermolate

Efcorbin

Efcortelan

Ficortril

Genacort

Hycortol

Hycortole

Permicort

Proctocort

Tarcortin

Traumaide

Alacort

Cleiton

Cortril

Dihydrocostisone

Hytone lotion

Hidro-Colisona

Hydro-Adreson

Scheroson F

Incortin-H

Reichsteins substance M

Cort-Dome

Domolene-HC

Epiderm H

Esiderm H

Otosone-F

Polcort H

Cortolotion

Cortoxide

Cremesone

Eldercort

Heb-Cort

Maintasone

Delacort

Dioderm

Eldecort

Epicort

Mildison

Penecort

Rectoid

Anflam

Hydrocorticosterone

Hydroxycortisone

H-Cort

Hydro-Colisona

Cortisol alcohol

Incortin-hydrogen

Ala-Scalp

Aeroseb-HC

Barseb HC

Dermocortal

Nutracort

Synacort

Timocort

Evacort

Komed HC

Hydrocortisone base

Lacticare-HC

Texacort lotion 25

Ala-Cort

Anti-inflammatory hormone

Hydrocortisone alcohol

Algicirtis

Aquacort

Cortesal

Cortisolonum

Flexicort

Hidalone

Hytisone

Kyypakkaus

Lactisona

Lubricort

Meusicort

Milliderm

Sanatison

Schericur

Sigmacort

Stiefcorcil

Texacort

Amberin

Cutisol

Dermil

Uniderm

Foille Insetti

Gyno-Cortisone

Transderma H

Basan-Corti

Clear aid

Cremicort-H

Dome-cort

Neosporin-H Ear

Remederm HC

Aquanil HC

Cortisporin Otico

Derm-Aid

Heb Cort

Scalpicin Capilar

Systral Hydrocort

Prevex HC

Cortisporin

Efcortelin

Fiocortril

Hidrocortisona

Hydrocortisone free alcohol

Hydrocortisonum

Proctofoam

Alphaderm

Hydracort

Medicort

Otocort

Zenoxone

Drotic

Vytone

11beta-Hydroxycortisone

Nystaform-HC

Aeroseb HC

CaldeCORT Spray

Pediotic Suspension

VoSol HC

Idrocortisone

17alpha-Hydroxycorticosterone

Hydrocortal

Hydroskin

Otalgine

Otobiotic

Protocort

Hysone

Racet

Ef corlin

11beta-Hydrocortisone

Compound F

Lacticare HC

Compound F (kendall)

11-beta-Hydrocortisone

11-beta-Hydroxycortisone

Hydrocortisone (Cortisol)

Chronocort

Hydrocort

Plenadren

Preparation H Hydrocortisone Cream

Neo-Cort-Dome

11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione

Otic-Neo-Cort-Dome

11beta,17,21-Trihydroxypregn-4-ene-3,20-dione

NSC 10483

HC

UNII-WI4X0X7BPJ

3Hcortisol

(11beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione

Prestwick_265

4-Pregnene-11beta,17alpha,21-triol-3,20-dione

CHEBI:17650

11beta,17alpha,21-Trihydroxypregn-4-ene-3,20-dione

NSC10483

11.beta.-Hydrocortisone

Dermaspray

MFCD00011654

NSC-10483

WI4X0X7BPJ

(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopentaaphenanthren-3-one

11beta,17,21-Trihydroxyprogesterone

11.beta.-Hydroxycortisone

Ophthocort

Terra-cortril

MLS000069609

17.alpha.-Hydroxycorticosterone

Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11beta)-

4-Pregnen-11beta,17alpha,21-triol-3,20-dione

Idrocortisone DCIT

Genacort (lotion)

Anucort

Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11b)-

Prepcort

SMR000059022

DSSTox_CID_714

Hydrocortisonum INN-Latin

Proctozone HC

Scalp-Cort

Hidrocortisona INN-Spanish

Rectasol-HC

Anucort-HC

Hydro-RX

DSSTox_RID_75753

DSSTox_GSID_20714

(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopentaaphenanthren-3(2H)-one

HC (HYDROCORTISONE)

Corhydron

(11alpha,14beta)-11,17,21-Trihydroxypregn-4-Ene-3,20-Dione

DuoCort

HYDROCORTISONE IN ABSORBASE

Proctosol-HC

HC #1

HC #4

Acticort (TN)

Colocort (TN)

(1S,10S,11S,15S,17S,2R,14R)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyl tetracyclo8.7.0.0<2,7>.0<11,15>heptadec-6-en-5-one

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo8.7.0.0^{2,7}.0^{11,15}heptadec-6-en-5-one

SMR000653523

Cortef (TN)

Hytone (TN)

Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11.beta.)-

CCRIS 5854

component of Otalgine

Anusol HC (TN)

component of Lubricort

COR-OTICIN

HSDB 3339

EINECS 200-020-1

component of Neo-Cort-Dome

Cortizol

Efmody

AI3-25006

3h-cortisol

11beta-cortisol

CAS-50-23-7

11-Hydrocortisone

Plenadren (TN)

NCGC00022848-06

11b-Hydrocortisone

Kendalls compound F

Hydrocortisone USP:INN:BAN:JAN

Drotic (Salt/Mix)

11b-Hydroxycortisone

Otocort (Salt/Mix)

Pregn-4-ene-3,20-dione, 11beta,17,21-trihydroxy-

Otalgine (Salt/Mix)

Hydrocortisone, 98%

11,17,21-Trihydroxypregn-4-ene-3,20-dione

Alphaderm (Salt/Mix)

Hydrocortisone, topical

Otobiotic (Salt/Mix)

Reichsteins substance M

4p6x

Cort-Quin (Salt/Mix)

Cortisporin (Salt/Mix)

VoSol HC (Salt/Mix)

11a-Hydroxycorticosterone

17a-Hydroxycorticosterone

Opera_ID_1292

Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11-beta)-

Prestwick0_000447

Prestwick1_000447

Prestwick2_000447

Prestwick3_000447

Epitope ID:174851

UPCMLD-DP133

EC 200-020-1

H 4001

SCHEMBL4148

Neo-Cort-Dome (Salt/Mix)

Lopac0_000594

11alpha-Hydroxycorticosterone

BSPBio_000494

MLS001148103

MLS002207135

MLS002222189

MLS002548868

SPBio_002433

BPBio1_000544

CHEMBL389621

GTPL2868

Pediotic Suspension (Salt/Mix)

DTXSID7020714

UPCMLD-DP133:001

BDBM13775

Otic-Neo-Cort-Dome (Salt/Mix)

2v95

Hydrocortisone (JP17/USP/INN)

HMS1569I16

HMS2090M04

HMS2096I16

HMS2230B18

HMS2235F17

HMS3259C05

HMS3261H10

HMS3713I16

Hydrocortisone, >=98% (HPLC)

Vioform-Hydrocortisone (Salt/Mix)

11b,17,21-Trihydroxyprogesterone

BCP09054

HY-N0583

Tox21_110883

Tox21_200815

Tox21_500594

LMST02030001

s1696

SBB012589

ZINC13540519

AKOS001582651

Tox21_110883_1

CCG-204683

DB00741

LP00594

MCULE-8953627920

NC00456

SDCCGSBI-0050576.P003

11.beta.,17,21-trihydroxyprogesterone

SMP1_000156

NCGC00022848-07

NCGC00022848-09

NCGC00022848-10

NCGC00022848-11

NCGC00022848-12

NCGC00022848-13

NCGC00022848-14

NCGC00022848-15

NCGC00022848-17

NCGC00022848-26

NCGC00258369-01

NCGC00261279-01

(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopentaaphenanthren-3-one

AC-12902

AS-11651

BP-20390

NCI60_000118

ST069286

4-Pregnene-11alpha,21-triol 3,20-dione

B1951

EU-0100594

4-Pregnene-11b,17a,21-triol-3,20-dione

50H237

6861-EP2269977A2

6861-EP2270008A1

6861-EP2277565A2

6861-EP2277566A2

6861-EP2277567A1

6861-EP2277568A2

6861-EP2277569A2

6861-EP2277570A2

6861-EP2292227A2

6861-EP2292280A1

6861-EP2292615A1

6861-EP2292617A1

6861-EP2295409A1

6861-EP2298778A1

6861-EP2305679A1

6861-EP2308562A2

6861-EP2314590A1

6861-EP2371811A2

7062-EP2269977A2

7062-EP2292228A1

7062-EP2295411A1

7062-EP2298747A1

7062-EP2301931A1

7062-EP2308851A1

7062-EP2308880A1

7062-EP2311811A1

7062-EP2314585A1

C00735

D00088

J10114

U 1851

92372-EP2280008A2

92372-EP2289483A1

92372-EP2305257A1

Hydrocortisone, meets USP testing specifications

Pregn-4-ene-3, 11.beta.,17,21-trihydroxy-

11?,17?,21-Trihydroxypregn-4-ene-3,20-dione

A929789

Hydrocortisone, VETRANAL(TM), analytical standard

Q190875

SR-01000000139

Q-201211

SR-01000000139-3

11.beta.,17,21-Trihydroxypregn-4-ene-3,20-dione

BRD-K93568044-001-03-1

BRD-K93568044-001-11-4

BRD-K93568044-001-32-0

Hydrocortisone, BioReagent, suitable for cell culture

4-Pregnen-11.beta.,17.alpha.,21-triol-3,20-dione

4-Pregnene-11.beta.,17.alpha.,21-triol-3,20-dione

Pregn-4-ene-3,20-dione, 11.beta.,17,21-trihydroxy-

Z2786051549

(11beta)-11,17,21-Trihydroxy-pregn-4-ene-3,20-dione

11.beta.,17.alpha.,21-Trihydroxy-4-pregnene-3,20-dione

11.beta.,17.alpha.,21-Trihydroxypregn-4-ene-3,20-dione

B48448A1-24BA-47CA-8D9E-43E5BC949386

Hydrocortisone, British Pharmacopoeia (BP) Assay Standard

Pregn-4-ene-3, 11,17,21-trihydroxy-, (11.beta.)-

11,17,21-Trihydroxypregn-4-ene-3,20-dione, (11.beta.)-

Hydrocortisone, European Pharmacopoeia (EP) Reference Standard

Hydrocortisone, United States Pharmacopeia (USP) Reference Standard

Hydrocortisone-Water Soluble, BioReagent, suitable for cell culture

Hydrocortisone, gamma-irradiated, powder, BioXtra, suitable for cell culture

4-(6-chloro-4-oxoquinazolin-3(4H)-yl)-N-(3-methoxyphenyl)piperidine-1-carboxamide

Cortisol solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material

Hydrocortisone for peak identification, European Pharmacopoeia (EP) Reference Standard

Hydrocortisone solution, 50 muM, sterile-filtered, BioXtra, suitable for cell culture

Hydrocortisone, Pharmaceutical Secondary Standard; Certified Reference Material

(10R,13S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopentaaphenanthren-3-one
  Experimental Data
 hydrocortisone

Species Dose Unit Control(Avg days) Treatment(Avg days) Avg/Med Lifespan Change(%) Control(Max days) Treatment(Max days) Max Lifespan Change(%) Significant Strain Gender PubMed Avg/Med Lifespan Change tab
Caenorhabditis elegans 33.000000000000000 umol/L 9.000000000000000 NS N2 24134630 Inactive
  Experimental Data Visualization
 hydrocortisone

  Statistics Data
 hydrocortisone

Species Avg/Med Lifespan Change(%) Max Lifespan Change(%) Count Reference Count Data point
Caenorhabditis elegans 9.000000000000000 1 1
  Statistics Data Visualization
 hydrocortisone

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