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Compound Summary

guanfacine hydrochloride

Compound Information

guanfacine hydrochloride

Compound Name:	guanfacine hydrochloride
Compound CID:	71401
Synonyms:	guanfacine hydrochloride 29110-48-3 GUANFACINE HCL Tenex Intuniv More...
Iupac Name:	N-(diaminomethylidene)-2-(2,6-dichlorophenyl)acetamide;hydrochloride
InChI:	InChI=1S/C9H9Cl2N3O.ClH/c10-6-2-1-3-7(11)5(6)4-8(15)14-9(12)13;/h1-3H,4H2,(H4,12,13,14,15);1H
InChIKey:	DGFYECXYGUIODH-UHFFFAOYSA-N
Canonical Smiles:	C1=CC(=C(C(=C1)Cl)CC(=O)N=C(N)N)Cl.Cl
Isomeric Smiles:	C1=CC(=C(C(=C1)Cl)CC(=O)N=C(N)N)Cl.Cl
Molecular Weight:	282.5
Molecular Formula:	C9H10Cl3N3O

Compound Structure

2D Structure:

3D Structure:

Computed Properties

guanfacine hydrochloride

Molecular Weight:	282.5
Molecular Formula:	C9H10Cl3N3O
Hydrogen Bond Donor Count:	3
Hydrogen Bond Acceptor Count:	1
Rotatable Bond Count:	2
Heavy Atom Count:	16
Complexity:	256

Synonyms

guanfacine hydrochloride

guanfacine hydrochloride	guanfacine hydrochloride
guanfacine hydrochloride	29110-48-3
GUANFACINE HCL	Tenex
Intuniv	Guanfacine (hydrochloride)
Estulic	N-Carbamimidoyl-2-(2,6-dichlorophenyl)acetamide hydrochloride
29520-14-7	BS 100-141
N-(Aminoiminomethyl)-2,6-dichlorobenzeneacetamide hydrochloride	N-Amidino-2-(2,6-dichlorophenyl)acetamide hydrochloride
UNII-PML56A160O	SPD503
SPD 503	MLS000069745
PML56A160O	BS-100-141
MFCD00798230	SMR000058453
29110-48-3 (HCl)	DSSTox_CID_25157
DSSTox_RID_80708	DSSTox_GSID_45157
Connexyn	LON 798
CAS-29520-14-7	GUANFACINEHCL
Tenex (TN)	SR-01000075893
NCGC00015469-05	N-Amidino-2-(2,6-dichlorophenyl)acetamide monohydrochloride
EINECS 249-443-3	N-(Aminoiminomethyl)-2,6-dichlorophenylacetamide monohydrochloride
C9H10Cl3N3O	SPD-503
Benzeneacetamide, N-(aminoiminomethyl)-2,6-dichloro-, monohydrochloride	Prestwick_740
Guanfacine hydrochloride (JAN/USP)	Intuniv (TN)
Guanfacine hydrochloride USAN:USP:JAN	Opera_ID_1928
N-(diaminomethylidene)-2-(2,6-dichlorophenyl)acetamide hydrochloride	Benzeneacetamide, N-(aminoiminomethyl)-2,6-dichloro-, hydrochloride (1:1)
G 1043	N (Aminoiminomethyl)-2,6-dichlorobenzeneacetamide
SCHEMBL41681	MLS001077329
MLS002222252	(2,6-Dichlorophenyl)acetylguanidine Hydrochloride
CHEBI:5559	CHEMBL1200494
DTXSID2045157	SCHEMBL15603414
HMS1569C19	HMS3747E15
Pharmakon1600-01505435	BCP21710
N-(aminoiminomethyl)-2,6-dichloro-benzeneacetamide hydrochloride	Tox21_110159
Tox21_500519	N-(diaminomethylidene)-2-(2,6-dichlorophenyl)acetamide;hydrochloride
NSC759121	s4693
AKOS015966858	AKOS030242245
Tox21_110159_1	CCG-213439
CCG-220339	CS-1254
LP00519	NSC-759121
NCGC00015469-09	NCGC00093914-01
NCGC00093914-02	NCGC00180965-01
NCGC00261204-01	AS-12253
HY-17416	Guanfacine hydrochloride, >=98% (HPLC)
AB0011596	BS100-141
DB-047525	EU-0100519
FT-0630546	FT-0698181
G0414	D00606
T72238	A826918
J-017395	S-877503
SR-01000075893-1	SR-01000075893-3
SR-01000075893-6	Q27286641
N-Carbamimidoyl-2-(2,6-dichlorophenyl)-acetamide hydrochloride	Guanfacine hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material
Guanfacine hydrochloride, United States Pharmacopeia (USP) Reference Standard	N-bis(azanyl)methylidene-2-2,6-bis(chloranyl)phenylethanamide hydrochloride
N-(Aminoiminomethyl)-2,6-dichlorobenzeneacetamide Hydrochloride / N-Amidino-2-(2,6-dichlorophenyl)acetamide Hydrochloride

Experimental Data

guanfacine hydrochloride

Species	Dose	Unit	Control(Avg days)	Treatment(Avg days)	Avg/Med Lifespan Change(%)	Control(Max days)	Treatment(Max days)	Max Lifespan Change(%)	Significant	Strain	Gender	PubMed	Avg/Med Lifespan Change tab
Caenorhabditis elegans	33.000000000000000	umol/L			15.000000000000000				S	N2		33683565	Active
Caenorhabditis elegans	13.000000000000000	umol/L			15.000000000000000				S	N2		24134630	Active

Experimental Data Visualization

guanfacine hydrochloride

Statistics Data

guanfacine hydrochloride

Species	Avg/Med Lifespan Change(%)	Max Lifespan Change(%)	Count Reference	Count Data point
Caenorhabditis elegans	15.000000000000000		2	2

Statistics Data Visualization

guanfacine hydrochloride

Compound Name:

guanfacine hydrochloride

Compound CID:

71401

Synonyms:

guanfacine hydrochloride 29110-48-3 GUANFACINE HCL Tenex Intuniv More...

Iupac Name:

N-(diaminomethylidene)-2-(2,6-dichlorophenyl)acetamide;hydrochloride

InChI:

InChI=1S/C9H9Cl2N3O.ClH/c10-6-2-1-3-7(11)5(6)4-8(15)14-9(12)13;/h1-3H,4H2,(H4,12,13,14,15);1H

InChIKey:

DGFYECXYGUIODH-UHFFFAOYSA-N

Canonical Smiles:

C1=CC(=C(C(=C1)Cl)CC(=O)N=C(N)N)Cl.Cl

Isomeric Smiles:

C1=CC(=C(C(=C1)Cl)CC(=O)N=C(N)N)Cl.Cl

Molecular Weight:

282.5

Molecular Formula:

C9H10Cl3N3O

Molecular Weight:

282.5

Molecular Formula:

C9H10Cl3N3O

Hydrogen Bond Donor Count:

3

Hydrogen Bond Acceptor Count:

1

Rotatable Bond Count:

2

Heavy Atom Count:

16

Complexity:

256

guanfacine hydrochloride

29110-48-3

GUANFACINE HCL

Tenex

Intuniv

Guanfacine (hydrochloride)

Estulic

N-Carbamimidoyl-2-(2,6-dichlorophenyl)acetamide hydrochloride

29520-14-7

BS 100-141

N-(Aminoiminomethyl)-2,6-dichlorobenzeneacetamide hydrochloride

N-Amidino-2-(2,6-dichlorophenyl)acetamide hydrochloride

UNII-PML56A160O

SPD503

SPD 503

MLS000069745

PML56A160O

BS-100-141

MFCD00798230

SMR000058453

29110-48-3 (HCl)

DSSTox_CID_25157

DSSTox_RID_80708

DSSTox_GSID_45157

Connexyn

LON 798

CAS-29520-14-7

GUANFACINEHCL

Tenex (TN)

SR-01000075893

NCGC00015469-05

N-Amidino-2-(2,6-dichlorophenyl)acetamide monohydrochloride

EINECS 249-443-3

N-(Aminoiminomethyl)-2,6-dichlorophenylacetamide monohydrochloride

C9H10Cl3N3O

SPD-503

Benzeneacetamide, N-(aminoiminomethyl)-2,6-dichloro-, monohydrochloride

Prestwick_740

Guanfacine hydrochloride (JAN/USP)

Intuniv (TN)

Guanfacine hydrochloride USAN:USP:JAN

Opera_ID_1928

N-(diaminomethylidene)-2-(2,6-dichlorophenyl)acetamide hydrochloride

Benzeneacetamide, N-(aminoiminomethyl)-2,6-dichloro-, hydrochloride (1:1)

G 1043

N (Aminoiminomethyl)-2,6-dichlorobenzeneacetamide

guanfacine hydrochloride

29110-48-3

GUANFACINE HCL

Tenex

Intuniv

More...