Compound Summary
forskolin
Compound Information
forskolin
Compound Name: | forskolin |
Compound CID: | 47936 |
Synonyms: | forskolin Colforsin 66575-29-9 Coleonol colforsina More... |
Iupac Name: | [(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-5,6,6a,8,9,10-hexahydro-2H-benzo[f]chromen-5-yl] acetate |
InChI: | InChI=1S/C22H34O7/c1-8-19(5)11-14(25)22(27)20(6)13(24)9-10-18(3,4)16(20)15(26)17(28-12(2)23)21(22,7)29-19/h8,13,15-17,24,26-27H,1,9-11H2,2-7H3/t13-,15-,16-,17-,19-,20-,21+,22-/m0/s1 |
InChIKey: | OHCQJHSOBUTRHG-KGGHGJDLSA-N |
Canonical Smiles: | CC(=O)OC1C(C2C(CCC(C2(C3(C1(OC(CC3=O)(C)C=C)C)O)C)O)(C)C)O |
Isomeric Smiles: | CC(=O)O[C@H]1[C@H]([C@@H]2[C@]([C@H](CCC2(C)C)O)([C@@]3([C@@]1(O[C@@](CC3=O)(C)C=C)C)O)C)O |
Molecular Weight: | 410.5 |
Molecular Formula: | C22H34O7 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
forskolin
Molecular Weight: | 410.5 |
Molecular Formula: | C22H34O7 |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 7 |
Rotatable Bond Count: | 3 |
Heavy Atom Count: | 29 |
Complexity: | 747 |
Synonyms
forskolin
| forskolin | forskolin |
|---|---|
forskolin |
Colforsin |
66575-29-9 |
Coleonol |
colforsina |
colforsine |
colforsinum |
Boforsin |
Coleonolk |
UNII-1F7A44V6OU |
HL 362 |
7beta-Acetoxy-8,13-epoxy-1alpha,6beta,9alpha-trihydroxylabd-14-en-11-one |
(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-3-vinyldodecahydro-1H-benzofchromen-5-yl acetate |
L 75 1362B |
C22H34O7 |
(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxododecahydro-1H-benzofchromen-5-yl acetate |
CHEMBL52606 |
1F7A44V6OU |
CHEBI:42471 |
MFCD00082317 |
NSC375489 |
(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-5,6,6a,8,9,10-hexahydro-2H-benzofchromen-5-yl acetate |
66428-89-5 |
NCGC00024996-02 |
DSSTox_CID_20484 |
DSSTox_RID_79500 |
DSSTox_GSID_40484 |
1H-Naphtho(2,1-b)pyran-1-one, dodecahydro-5-(acetyloxy)-3-ethenyl-3,4a,7,7,10a-pentamethyl-6,10,10b-trihydroxy-, (3R-(3-alpha,4a-beta,5-beta,6-beta,6a-alpha,10-alpha,10a-beta,10b-alpha))- |
Colforsine French |
Colforsinum Latin |
Colforsina Spanish |
ForsLean |
Colforsin USAN:INN |
1H-Naphtho2,1-bpyran-1-one, 5-(acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-, (3R,4aR,5S,6S,6aS,10S,10aR,10bS)- |
FOK |
SMR000471881 |
CAS-66575-29-9 |
EINECS 266-410-9 |
NSC 357088 |
NSC 375489 |
Forskolin, Coleus forskohlii |
Ocufors |
Timsaponin-C |
Forskolin- Bio-X |
Forskolin - 10% |
Forskolin - 20% |
Forskolin - 40% |
Forskolin 20.0% |
Colforsin (USAN/INN) |
forskolin/ rolipram mixture |
MolMap_000021 |
7-beta-Acetoxy-8,13-epoxy-1-alpha,6-beta,9-alpha-trihydroxylabd-14-en-11-one |
SCHEMBL4928 |
(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-Dodecahydro-5,6,10,10b-tetrahydroxy-3,4a,7,7,10a-pentamethyl-3-vinyl-1H-naphtho(2,1-b)pyran-1-one 5-acetate |
1H-Naphtho(2,1-b)pyran-1-one, 5-(acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl- |
cid_47936 |
MLS001066384 |
MLS001333255 |
MLS001333256 |
MLS002172462 |
MLS002695942 |
Forskolin, analytical standard |
Forskohlii Root Extract (ForsLean)(20% forskohlin) |
REGID_for_CID_47936 |
GTPL5190 |
DTXSID8040484 |
BCBcMAP01_000132 |
OHCQJHSOBUTRHG-KGGHGJDLSA- |
AOB6380 |
Bio1_000443 |
Bio1_000932 |
Bio1_001421 |
HMS2235C17 |
HMS3267I16 |
HMS3412G19 |
HMS3676G19 |
ZINC3977779 |
Tox21_110940 |
Tox21_302399 |
BDBM50010261 |
HL-362 |
s2449 |
7beta-Acetoxy-8,13-epoxy-1alpha,6beta,9alpha-trihydroxy-labd-14-en-11-one |
AKOS024456384 |
Tox21_110940_1 |
ACN-035218 |
AM81249 |
CCG-268774 |
CS-1454 |
DB02587 |
LMPR0104030004 |
SMP1_000128 |
NCGC00024996-03 |
NCGC00024996-04 |
NCGC00024996-05 |
NCGC00024996-06 |
NCGC00024996-07 |
NCGC00024996-34 |
NCGC00177971-03 |
NCGC00255526-01 |
1H-Naphtho(2,1-b)pyran-1-one, 5-(acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-, (3R-(3alpha,4abeta,5beta,6beta,6aalpha,10alpha,10abeta,10balpha))- |
5-(Acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho(2,1-b)pyran-1-one |
AC-33150 |
AS-17443 |
BF164487 |
HY-15371 |
XF165210 |
XF165211 |
XF165212 |
L-751362B |
F0855 |
M-410 |
V0151 |
Y0448 |
7088-EP2280000A1 |
7088-EP2284169A1 |
7088-EP2287147A2 |
7088-EP2287161A1 |
7088-EP2287162A1 |
7088-EP2287165A2 |
7088-EP2287166A2 |
7088-EP2292620A2 |
7088-EP2295550A2 |
7088-EP2301931A1 |
7088-EP2301937A1 |
7088-EP2308562A2 |
7088-EP2311806A2 |
7088-EP2371811A2 |
C09076 |
D03584 |
MLS-0318096.0001 |
A850885 |
Q412747 |
SR-01000597378 |
Forskolin, For use in molecular biology applications |
Q-200888 |
SR-01000597378-1 |
BRD-K09602097-001-04-5 |
Forskolin, from Coleus forskohlii, >=98% (HPLC), powder |
Forskolin, United States Pharmacopeia (USP) Reference Standard |
(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-dodecahydro-1H-naphtho2,1-bpyran-5-yl acetate |
(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-3-vinyl-5,6,6a,8,9,10-hexahydro-2H-benzofchromen-5-yl acetate |
3R-(3 |
3R-(3?,4a?,5?,6?,6a?,10?,10a?,10b?)-5-(Acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho2,1-bpyran-1-one |
3R-(3a,4ab,5b,6b,6aa,10a,10ab,10ba)-5-(Acetyloxy)-3-e thenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho2,1-bpyran-1-one |
Experimental Data
forskolin
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -8.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
forskolin
Statistics Data
forskolin
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -8.000000000000000 | 1 | 1 |
Statistics Data Visualization
forskolin
