Compound Summary
fluvoxamine
Compound Information
fluvoxamine
Compound Name: | fluvoxamine |
Compound CID: | 5324346 |
Synonyms: | fluvoxamine 54739-18-3 Fluvoxaminum Fluvoxamina (Z)-Fluvoxamine More... |
Iupac Name: | 2-[(E)-[5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene]amino]oxyethanamine |
InChI: | InChI=1S/C15H21F3N2O2/c1-21-10-3-2-4-14(20-22-11-9-19)12-5-7-13(8-6-12)15(16,17)18/h5-8H,2-4,9-11,19H2,1H3/b20-14+ |
InChIKey: | CJOFXWAVKWHTFT-XSFVSMFZSA-N |
Canonical Smiles: | COCCCCC(=NOCCN)C1=CC=C(C=C1)C(F)(F)F |
Isomeric Smiles: | COCCCC/C(=N\OCCN)/C1=CC=C(C=C1)C(F)(F)F |
Molecular Weight: | 318.33 |
Molecular Formula: | C15H21F3N2O2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
fluvoxamine
Molecular Weight: | 318.33 |
Molecular Formula: | C15H21F3N2O2 |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 7 |
Rotatable Bond Count: | 9 |
Heavy Atom Count: | 22 |
Complexity: | 327 |
Synonyms
fluvoxamine
| fluvoxamine | fluvoxamine |
|---|---|
fluvoxamine |
54739-18-3 |
Fluvoxaminum |
Fluvoxamina |
(Z)-Fluvoxamine |
UNII-O4L1XPO44W |
Fluvoxaminum INN-Latin |
Fluvoxamina INN-Spanish |
2-(E)-5-methoxy-1-4-(trifluoromethyl)phenylpentylideneaminooxyethanamine |
CHEMBL814 |
O4L1XPO44W |
CHEBI:5138 |
Fluvoxamine INN:BAN |
(1E)-5-methoxy-1-4-(trifluoromethyl)phenylpentan-1-one O-(2-aminoethyl)oxime |
(E)-5-Methoxy-1-(4-(trifluoromethyl)phenyl)pentan-1-one O-(2-aminoethyl) oxime |
1-Pentanone, 5-methoxy-1-4-(trifluoromethyl)phenyl-,O-(2-aminoethyl)oxime, (1E)- |
DSSTox_CID_24002 |
DSSTox_RID_80097 |
DSSTox_GSID_44002 |
(E)-5-Methoxy-1-(4-(trifluoromethyl)phenyl)-pentan-1-one O-(2-aminoethyl) oxime |
1-Pentanone, 5-methoxy-1-(4-(trifluoromethyl)phenyl)-, O-(2-aminoethyl)oxime, (E)- |
Fluvoxamine (INN) |
CAS-54739-18-3 |
C15H21F3N2O2 |
N06AB08 |
NCGC00018193-06 |
FVX |
Prestwick2_000995 |
Prestwick3_000995 |
Lopac0_000495 |
SCHEMBL33983 |
BSPBio_001089 |
BIDD:GT0609 |
BPBio1_001199 |
DTXSID2044002 |
HY-B0103 |
Tox21_110837 |
BDBM50028091 |
ZINC12466082 |
AKOS016003882 |
Tox21_110837_1 |
AC-1679 |
CCG-204586 |
CS-1840 |
DB00176 |
SDCCGSBI-0050479.P002 |
2-({(1E)-5-methoxy-1-4-(trifluoromethyl)phenylpentylidene}amino)oxyethanamine |
NCGC00018193-04 |
NCGC00018193-05 |
NCGC00018193-07 |
NCGC00018193-08 |
NCGC00018193-11 |
NCGC00018193-21 |
NCGC00021870-04 |
NCGC00021870-05 |
AS-15332 |
O893 |
AB0016707 |
AB00514702 |
39F183 |
C07571 |
D07984 |
AB00513735_05 |
AB00513735_06 |
A830353 |
BRD-K53517854-050-03-2 |
Q27259474 |
(E)-5-Methoxy-4-(trifluormethyl)valerophenon-O-(2-aminoethyl)oxim |
(2-aminoethoxy)({5-methoxy-1-4-(trifluoromethyl)phenylpentylidene})amine |
5-methoxy-1-4-(trifluoromethyl)phenyl-1-pentanone O-(2-aminoethyl)oxime |
Experimental Data
fluvoxamine
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drosophila melanogaster | 20.000000000000000 | umol/L | 44.630000000000000 | 50.740000000000000 | 13.680000000000000 | S | FEMALES | 33008901 | Active | ||||
| Caenorhabditis elegans | 100.000000000000000 | umol/L | 15.780000000000000 | 14.910000000000000 | -5.466000000000000 | NS | N2 | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 10.000000000000000 | umol/L | 17.010000000000000 | 15.370000000000000 | -9.644000000000000 | NS | N2 | 33008901 | Inactive | ||||
| Drosophila melanogaster | 200.000000000000000 | umol/L | 43.170000000000000 | 42.490000000000000 | -1.565000000000000 | NS | MALES | 33008901 | Inactive |
Experimental Data Visualization
fluvoxamine
Statistics Data
fluvoxamine
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -5.466000000000000 | 1 | 2 | |
| Drosophila melanogaster | 13.680000000000000 | 1 | 2 |
Statistics Data Visualization
fluvoxamine
