Compound Summary
fluoxetine
Compound Information
fluoxetine
Compound Name: | fluoxetine |
Compound CID: | 3386 |
Synonyms: | fluoxetine 54910-89-3 Prozac Pulvules Portal More... |
Iupac Name: | N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine |
InChI: | InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3 |
InChIKey: | RTHCYVBBDHJXIQ-UHFFFAOYSA-N |
Canonical Smiles: | CNCCC(C1=CC=CC=C1)OC2=CC=C(C=C2)C(F)(F)F |
Isomeric Smiles: | CNCCC(C1=CC=CC=C1)OC2=CC=C(C=C2)C(F)(F)F |
Molecular Weight: | 309.33 |
Molecular Formula: | C17H18F3NO |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
fluoxetine
Molecular Weight: | 309.33 |
Molecular Formula: | C17H18F3NO |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 6 |
Heavy Atom Count: | 22 |
Complexity: | 308 |
Synonyms
fluoxetine
| fluoxetine | fluoxetine |
|---|---|
fluoxetine |
54910-89-3 |
Prozac |
Pulvules |
Portal |
Eufor |
Animex-On |
Fluoxetina |
Fluoxetina Spanish |
Fluoxetinum |
Fluoxetinum INN-Latin |
Fluoxetina INN-Spanish |
N-methyl-3-phenyl-3-4-(trifluoromethyl)phenoxypropan-1-amine |
Fontex |
Reconcile |
Fluctine |
Fluoxac |
Fludac |
Fluxil |
(+-)-N-Methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine |
(+-)-N-Methyl-3-phenyl-3-((alpha,alpha,alpha-trifluoro-p-tolyl)oxy)propylamine |
N-Methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine |
CHEMBL41 |
Fluoxetin |
dl-3-(p-Trifluoromethylphenoxy)-N-methyl-3-phenylpropylamine |
Methyl({3-phenyl-3-4-(trifluoromethyl)phenoxypropyl})amine |
Symbyax |
CHEBI:86990 |
Selfemra |
NSC-283480 |
(+/-)-Fluoxetine |
HSDB 6633 |
NCGC00015428-08 |
(+/-) -Fluoxetine |
Fluval |
n-methyl-3-phenyl-3-(4-(trifluoromethyl)phenoxy)propan-1-amine |
Methyl-3-phenyl-3-(4-trifluoromethyl-phenoxy)-propyl-amine |
DSSTox_CID_3067 |
DSSTox_RID_76861 |
DSSTox_GSID_23067 |
Fluoxetine USAN:INN:BAN |
N-methyl-3-phenyl-3-{4-(trifluoromethyl)phenyloxy}propan-1-amine |
Fluoxetine (TN) |
CAS-54910-89-3 |
Fluoxetine (USAN/INN) |
methyl{3-phenyl-3-4-(trifluoromethyl)phenoxypropyl}amine |
Spectrum_001679 |
SpecPlus_000723 |
Prestwick0_000511 |
Prestwick1_000511 |
Prestwick2_000511 |
Prestwick3_000511 |
Spectrum2_001658 |
Spectrum3_001648 |
Spectrum4_000613 |
Spectrum5_001518 |
Benzenepropamine, N-methyl-gamma-(4-(trifluoromethyl)phenoxy)-, (+-)- |
Biomol-NT_000152 |
Epitope ID:224550 |
(+) or (-)-N-Methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine |
Benzenepropanamine, N-methyl-gamma-(4-(trifluoromethyl)phenoxy)-, (+-)- |
SCHEMBL8353 |
(+) or (-)-N-Methyl-3-phenyl-3-((alpha,alpha,alpha-trifluoro-p-tolyl)oxy)propylamine |
Lopac0_000558 |
BSPBio_000461 |
BSPBio_003375 |
GTPL203 |
KBioGR_001166 |
KBioSS_002159 |
cid_62857 |
DivK1c_006819 |
SPBio_001815 |
SPBio_002382 |
BPBio1_000354 |
BPBio1_000509 |
CHEBI:5118 |
DTXSID7023067 |
BDBM30130 |
KBio1_001763 |
KBio2_002159 |
KBio2_004727 |
KBio2_007295 |
KBio3_002595 |
3-(p-Trifluoromethylphenoxy)-N-methyl-3-phenylpropylamine |
HMS2090H14 |
(+/-)-N-Methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine |
ALBB-025606 |
AMY32526 |
BCP28440 |
HY-B0102 |
N-Methyl-3-phenyl-3-4-(trifluoromethyl)phenoxy-1-propanamine |
Tox21_110144 |
(+/-)-N-Methyl-3-p-(p-trifluoromethylphenoxy)-3-phenylpropylamine |
(+/-)-N-Methyl-3-phenyl-3-4-(trifluoromethyl)phenoxypropylamine |
(+/-)-N-Methyl-gamma-4-(trifluoromethyl)phenoxybenzenepropanamine |
AB9783 |
BBL012251 |
MFCD00072041 |
NS-140 |
NSC283480 |
SBB017267 |
STK734483 |
AKOS003663021 |
Tox21_110144_1 |
AC-8478 |
CCG-204648 |
DB00472 |
NSC 283480 |
NSC 758685 |
SDCCGSBI-0050541.P004 |
(+/-)-N-Methyl-3-phenyl-3-(alpha,alpha,alpha-trifluoro-p-tolyl)oxypropylamine |
NCGC00015428-06 |
NCGC00015428-07 |
NCGC00015428-10 |
NCGC00015428-11 |
NCGC00015428-12 |
NCGC00015428-13 |
NCGC00015428-15 |
NCGC00015428-27 |
NCGC00024879-03 |
NCGC00024879-04 |
AS-44989 |
ST076807 |
SBI-0050541.P003 |
AB0107059 |
DB-015148 |
AB00053774 |
FT-0626489 |
D00326 |
AB00053774-13 |
AB00053774-14 |
AB00053774_15 |
AB00053774_16 |
L000931 |
Q422244 |
BRD-A31159102-001-01-9 |
BRD-A31159102-003-05-6 |
BRD-A31159102-003-16-3 |
SR-01000002988-18 |
LY-110140;LY 110140;LY110140 |
N-methyl 3-(p-trifluoromethylphenoxy)-3-phenylpropylamine |
N-Methyl-3-phenyl-3-(p-trifluoromethylphenoxy)propylamine |
benzenepropanamine, N-methyl-gamma-4-(trifluoromethyl)phenoxy- |
N-Methyl-3-phenyl-3-4-(trifluoromethyl)phenoxy-1-propanamine # |
Benzenepropanamine, N-methyl-gamma-4-(trifluoromethyl)phenoxy-, (+/-)- |
methyl{3-phenyl-3-4-(trifluoromethyl)phenoxypropyl}amine hydrochloride |
N-methyl-3-4-(trifluoromethyl)phenoxy-3-(3-tritiophenyl)propan-1-amine |
N-methyl-3-phenyl-3-(alpha,alpha,alpha-trifluoro-p-tolyl)oxypropylamine |
(.+/-.)-N-Methyl-3-phenyl-3-(.alpha.,.alpha.,.alpha.-trifluoro-p-tolyl)oxypropylamine |
(.+/-.)-N-Methyl-3-phenyl-3-(.alpha.,la,.alpha.-trifluoro-p-tolyl)oxypropylamine |
Benzenepropanamine, N-methyl-.gamma.-4-(trifluoromethyl)phenoxy-, (.+/-.)- |
57226-07-0 |
Experimental Data
fluoxetine
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 1000.000000000000000 | umol/L | Unclear | N2 | 33683565 | ||||||||
| Caenorhabditis elegans | 100.000000000000000 | umol/L | 20.060000000000000 | 22.060000000000000 | 0.100000000000000 | S | N2 | 33352493 | Active | ||||
| Caenorhabditis elegans | 100.000000000000000 | umol/L | 16.400000000000000 | 16.900000000000000 | 3.200000000000000 | NS | N2 | 33596295 | Inactive |
Experimental Data Visualization
fluoxetine
Statistics Data
fluoxetine
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 3.200000000000000 | 3 | 3 |
Statistics Data Visualization
fluoxetine
