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Compound Summary

finasteride

Compound Information

finasteride

Compound Name:	finasteride
Compound CID:	57363
Synonyms:	finasteride 98319-26-7 Proscar Propecia Finastid More...
Iupac Name:	(1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-tert-butyl-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide
InChI:	InChI=1S/C23H36N2O2/c1-21(2,3)25-20(27)17-8-7-15-14-6-9-18-23(5,13-11-19(26)24-18)16(14)10-12-22(15,17)4/h11,13-18H,6-10,12H2,1-5H3,(H,24,26)(H,25,27)/t14-,15-,16-,17+,18+,22-,23+/m0/s1
InChIKey:	DBEPLOCGEIEOCV-WSBQPABSSA-N
Canonical Smiles:	CC12CCC3C(C1CCC2C(=O)NC(C)(C)C)CCC4C3(C=CC(=O)N4)C
Isomeric Smiles:	C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2C(=O)NC(C)(C)C)CC[C@@H]4[C@@]3(C=CC(=O)N4)C
Molecular Weight:	372.5
Molecular Formula:	C23H36N2O2

Compound Structure

2D Structure:

3D Structure:

Computed Properties

finasteride

Molecular Weight:	372.5
Molecular Formula:	C23H36N2O2
Hydrogen Bond Donor Count:	2
Hydrogen Bond Acceptor Count:	2
Rotatable Bond Count:	2
Heavy Atom Count:	27
Complexity:	678

Synonyms

finasteride

finasteride	finasteride
finasteride	98319-26-7
Proscar	Propecia
Finastid	Prostide
Chibro-Proscar	MK-906
Finpecia	Finasterida
Finasteridum	MK 906
UNII-57GNO57U7G	(5alpha,17beta)-(1,1-Dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide
(4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-tert-butyl-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno5,4-fquinoline-7-carboxamide	CHEMBL710
N-tert-Butyl-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxamide	57GNO57U7G
CHEBI:5062	(1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-tert-butyl-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno5,4-fquinoline-1-carboxamide
(4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-(tert-butyl)-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno5,4-fquinoline-7-carboxamide	N-tert-Butyl-3-oxo-4-aza-5alpha-androst-1-en-17beta-carboxamide
MFCD00869737	Finasteridum INN-Latin
C23H36N2O2	Finasterida INN-Spanish
DSSTox_CID_625	DSSTox_RID_75699
DSSTox_GSID_20625	(4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-(1,1-dimethylethyl)-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno5,4-fquinoline-7-carboxamide
Andozac	4-Azaandrost-1-ene-17-carboxamide, N-(1,1-dimethylethyl)-3-oxo-, (5alpha,17beta)-
Propecia (TN)	SMR000466304
Proscar (TN)	MK 0906
MK-0906	CCRIS 7438
HSDB 6793	MK906
SR-01000759414	BRN 4269024
L-652,931	17beta-(N-tert-butylcarbamoyl)-4-aza-5 alpha-androst-1-en-3-one
NCGC00016965-01	Finasteride USAN:USP:INN:BAN
N-(2-Methyl-2-propyl)-3-oxo-4-aza-5-alpha-androst-1-ene-17-beta-carboxamide	CAS-98319-26-7
YM-152	KS-1058
Finasteride (Proscar)	Prestwick0_000717
Prestwick1_000717	Prestwick2_000717
Prestwick3_000717	N-(2-methyl-2-propyl)-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxamide
SCHEMBL5509	BSPBio_000933
MLS000759404	MLS001165768
MLS001424046	Finasteride (JAN/USP/INN)
SPBio_002854	BPBio1_001027
GTPL6818	DTXSID3020625
BCPP000229	HMS1570O15
HMS2051F09	HMS2090G22
HMS2097O15	HMS2235L23
HMS3714O15	4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno5,4-fquinoline-7-carboxylic acid tert-butylamide
ACT02599	EX-A1951
ZINC3782599	Tox21_110717
Tox21_201506	Tox21_302744
BDBM50334788	NSC741485
NSC757443	s1197
AKOS015894916	Tox21_110717_1
BCP9000685	CCG-100937
CS-1767	DB01216
Finasteride, >=98% (HPLC), powder	NC00187
NSC 741485	NSC 759318
NSC-741485	NSC-757443
NCGC00093560-05	NCGC00256334-01
NCGC00259057-01	BF164456
CPD000466304	HY-13635
BCP0726000222	AB00513901
D00321	J10122
32329-EP2272827A1	32329-EP2275420A1
32329-EP2280012A2	32329-EP2281815A1
32329-EP2292615A1	32329-EP2295055A2
32329-EP2295416A2	32329-EP2295426A1
32329-EP2295427A1	32329-EP2298748A2
32329-EP2298764A1	32329-EP2298765A1
32329-EP2298768A1	32329-EP2301928A1
32329-EP2301933A1	32329-EP2305640A2
32329-EP2305642A2	32329-EP2305671A1
32329-EP2311453A1	32329-EP2311808A1
32329-EP2311825A1	32329-EP2311827A1
32329-EP2311829A1	32329-EP2311840A1
AB00513901-07	AB00513901-08
AB00513901_09	Finasteride, VETRANAL(TM), analytical standard
319F267	A845840
Q424167	SR-01000759414-4
SR-01000759414-6	BRD-K01095011-001-03-5
BRD-K01095011-001-15-9	Finasteride, British Pharmacopoeia (BP) Reference Standard
Finasteride, European Pharmacopoeia (EP) Reference Standard	(1-PHENYL-METH-(E)-YLIDENE-AMINO)-ACETICACIDETHYLESTER
(17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-androst-1-en-3-one	Finasteride, United States Pharmacopeia (USP) Reference Standard
(5?,17?)-N-(1,1-Dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide	4-Azaandrost-1-ene-17-carboxamide, N-(1,1-dimethylethyl)-3-oxo-, (5-alpha,17-beta)-
4-Azaandrost-1-ene-17-carboxamide,1-dimethylethyl)-3-oxo-, (5.alpha., 17.beta.)-	Finasteride for peak identification, European Pharmacopoeia (EP) Reference Standard
(1S,2R,7R,10S,11S,14S,15S)-N-tert-butyl-2,15-dimethyl-5-oxo-6-azatetracyclo8.7.0.0^{2,7}.0^{11,15}heptadec-3-ene-14-carboxamide	(1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-isobutyl-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno5,4-fquinoline-1-carboxamide
(1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-isobutyl-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno5,4-fquinoline-1-carboxamide;Finasteride	(4AR,4BS,6AS,7S,9AS,9BS,11AR)-4A,6A-DIMETHYL-2-OXO-2,4A,4B,5,6,6A,7,8,9,9A,9B,10,11,11A-TETRADECAHYDRO-1H-INDENO5,4-FQUINOLINE-7-CARBOXYLIC ACID TERT-BUTYLAMIDE
(4aR,4bS,6aS,9aS,9bS,11aR)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno5,4-fquinoline-7-carboxylic acid tert-butylamide	(4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno5,4-fquinoline-7-carboxylic acid tert-butylamide
(4aR,6aS,11aR)-4a,6a-Dimethyl-2-oxo-hexadecahydro-indeno5,4-fquinoline-7-carboxylic acid tert-butylamide	(4aR,6aS,7S)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno5,4-fquinoline-7-carboxylic acid tert-butylamide
(4aR,6aS,7S,11aR)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno5,4-fquinoline-7-carboxylic acid tert-butylamide	(R)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno5,4-fquinoline-7-carboxylic acid tert-butylamide
140375-21-9	4a,6a,9a-Trimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno5,4-fquinoline-7-carboxylic acid (Finasteride)
4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno5,4-fquinoline-7-carboxylic acid tert-butylamide(Finasteride)

Experimental Data

finasteride

Species	Dose	Unit	Control(Avg days)	Treatment(Avg days)	Avg/Med Lifespan Change(%)	Control(Max days)	Treatment(Max days)	Max Lifespan Change(%)	Significant	Strain	Gender	PubMed	Avg/Med Lifespan Change tab
Caenorhabditis elegans	33.000000000000000	umol/L			-7.000000000000000				NS	N2		24134630	Inactive

Experimental Data Visualization

finasteride

Statistics Data

finasteride

Species	Avg/Med Lifespan Change(%)	Max Lifespan Change(%)	Count Reference	Count Data point
Caenorhabditis elegans	-7.000000000000000		1	1

Statistics Data Visualization

finasteride

Compound Name:

finasteride

Compound CID:

57363

Synonyms:

finasteride 98319-26-7 Proscar Propecia Finastid More...

Iupac Name:

(1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-tert-butyl-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide

InChI:

InChI=1S/C23H36N2O2/c1-21(2,3)25-20(27)17-8-7-15-14-6-9-18-23(5,13-11-19(26)24-18)16(14)10-12-22(15,17)4/h11,13-18H,6-10,12H2,1-5H3,(H,24,26)(H,25,27)/t14-,15-,16-,17+,18+,22-,23+/m0/s1

InChIKey:

DBEPLOCGEIEOCV-WSBQPABSSA-N

Canonical Smiles:

CC12CCC3C(C1CCC2C(=O)NC(C)(C)C)CCC4C3(C=CC(=O)N4)C

Isomeric Smiles:

C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2C(=O)NC(C)(C)C)CC[C@@H]4[C@@]3(C=CC(=O)N4)C

Molecular Weight:

372.5

Molecular Formula:

C23H36N2O2

Molecular Weight:

372.5

Molecular Formula:

C23H36N2O2

Hydrogen Bond Donor Count:

2

Hydrogen Bond Acceptor Count:

2

Rotatable Bond Count:

2

Heavy Atom Count:

27

Complexity:

678

finasteride

98319-26-7

Proscar

Propecia

Finastid

Prostide

Chibro-Proscar

MK-906

Finpecia

Finasterida

Finasteridum

MK 906

UNII-57GNO57U7G

(5alpha,17beta)-(1,1-Dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide

(4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-tert-butyl-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno5,4-fquinoline-7-carboxamide

CHEMBL710

N-tert-Butyl-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxamide

57GNO57U7G

CHEBI:5062

(1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-tert-butyl-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno5,4-fquinoline-1-carboxamide

(4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-(tert-butyl)-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno5,4-fquinoline-7-carboxamide

N-tert-Butyl-3-oxo-4-aza-5alpha-androst-1-en-17beta-carboxamide

MFCD00869737

Finasteridum INN-Latin

C23H36N2O2

Finasterida INN-Spanish

DSSTox_CID_625

DSSTox_RID_75699

DSSTox_GSID_20625

(4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-(1,1-dimethylethyl)-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno5,4-fquinoline-7-carboxamide

Andozac

4-Azaandrost-1-ene-17-carboxamide, N-(1,1-dimethylethyl)-3-oxo-, (5alpha,17beta)-

Propecia (TN)

SMR000466304

Proscar (TN)

MK 0906

MK-0906

CCRIS 7438

HSDB 6793

MK906

SR-01000759414

BRN 4269024

L-652,931

17beta-(N-tert-butylcarbamoyl)-4-aza-5 alpha-androst-1-en-3-one

NCGC00016965-01

Finasteride USAN:USP:INN:BAN

finasteride

98319-26-7

Proscar

Propecia

Finastid

More...