Compound Summary
famotidine
Compound Information
famotidine
Compound Name: | famotidine |
Compound CID: | 5702160 |
Synonyms: | famotidine 76824-35-6 PEPCID Pepcid AC Famodil More... |
Iupac Name: | 3-[[2-(diaminomethylideneamino)-1,3-thiazol-4-yl]methylsulfanyl]-N'-sulfamoylpropanimidamide |
InChI: | InChI=1S/C8H15N7O2S3/c9-6(15-20(12,16)17)1-2-18-3-5-4-19-8(13-5)14-7(10)11/h4H,1-3H2,(H2,9,15)(H2,12,16,17)(H4,10,11,13,14) |
InChIKey: | XUFQPHANEAPEMJ-UHFFFAOYSA-N |
Canonical Smiles: | C1=C(N=C(S1)N=C(N)N)CSCCC(=NS(=O)(=O)N)N |
Isomeric Smiles: | C1=C(N=C(S1)N=C(N)N)CSCC/C(=N/S(=O)(=O)N)/N |
Molecular Weight: | 337.5 |
Molecular Formula: | C8H15N7O2S3 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
famotidine
Molecular Weight: | 337.5 |
Molecular Formula: | C8H15N7O2S3 |
Hydrogen Bond Donor Count: | 4 |
Hydrogen Bond Acceptor Count: | 8 |
Rotatable Bond Count: | 7 |
Heavy Atom Count: | 20 |
Complexity: | 469 |
Synonyms
famotidine
| famotidine | famotidine |
|---|---|
famotidine |
76824-35-6 |
PEPCID |
Pepcid AC |
Famodil |
Gastridin |
Pepcidine |
Pepdine |
Quamatel |
Gaster |
Pepdul |
Pepcid RPD |
YM-11170 |
Famotidine (Pepcid) |
3-({2-(diaminomethylidene)amino-1,3-thiazol-4-yl}methyl)sulfanyl-N-sulfamoylpropanimidamide |
MK-208 |
MK 208 |
CHEBI:4975 |
YM 11170 |
3-(2-Guanidinothiazol-4-ylmethylthio)-N1-sulfamoylpropionamide |
L 643341 |
N-(Aminosulfonyl)-3-(2-(diaminomethyleneamino)-4-thiazolylmethylthio)propanamidine |
UNII-5QZO15J2Z8 |
XUFQPHANEAPEMJ-UHFFFAOYSA- |
C8H15N7O2S3 |
3-(((2-((Diaminomethylene)amino)thiazol-4-yl)methyl)thio)-N-sulfamoylpropanimidamide |
Pepcid AC Gelcaps |
SMR000058961 |
Pepcid (TN) |
CHEMBL902 |
3-2-(Aminoiminomethyl)amino-4-thiazolylmethylthio-N-(aminosulfonyl)propanimidamide |
SR-05000001440 |
5QZO15J2Z8 |
NCGC00015446-05 |
FO9 |
Prestwick_212 |
CAS-76824-35-6 |
Fluxid (TN) |
HS-0054 |
YM-1170 |
Prestwick2_000104 |
Prestwick3_000104 |
Lopac-F-6889 |
F0530 |
SCHEMBL972 |
SCHEMBL974 |
F 6889 |
Lopac0_000497 |
BSPBio_000088 |
MLS000028583 |
MLS000758205 |
MLS001423994 |
BIDD:GT0759 |
BPBio1_000098 |
Famotidine (JP17/USP/INN) |
BDBM22891 |
cid_5702160 |
HMS1568E10 |
HMS2051A07 |
HMS2089I12 |
HMS2095E10 |
HMS2231I22 |
HMS3261D15 |
HMS3712E10 |
HMS3884J03 |
HY-B0377 |
Tox21_500497 |
BDBM50103514 |
PDSP1_000398 |
PDSP2_000396 |
s2078 |
STK527689 |
AKOS005460541 |
AKOS015994617 |
CCG-100767 |
CCG-220104 |
CCG-221801 |
MCULE-1972636463 |
NC00017 |
SDCCGSBI-0050481.P004 |
3-2-(diaminomethylideneamino)-1,3-thiazol-4-ylmethylsulfanyl-N-sulfamoylpro |
Propanimidamide, 3-2-aminoiminomethyl)amino-4-thiazoylmethylthio-N-(aminosulfonyl) |
NCGC00015446-01 |
NCGC00015446-02 |
NCGC00015446-03 |
NCGC00015446-04 |
NCGC00015446-06 |
NCGC00015446-08 |
NCGC00018276-01 |
NCGC00018276-02 |
NCGC00093899-01 |
NCGC00093899-02 |
NCGC00093899-03 |
NCGC00188952-01 |
NCGC00261182-01 |
(1Z)-3-({2-(diaminomethylidene)amino-1,3-thiazol-4-yl}methyl)sulfanyl-N-sulfamoylpropanimidamide" |
(1Z)-N-(aminosulfonyl)-3-({2-(diaminomethylidene)amino-1,3-thiazol-4-yl}methyl)thiopropanimidamide |
AC-11713 |
AC-31723 |
K328 |
SBI-0050481.P003 |
EU-0100497 |
ST51001070 |
D00318 |
AB00383032_11 |
824F356 |
A838850 |
A899959 |
L003830 |
L013386 |
SR-01000075883 |
SR-01000075883-1 |
SR-05000001440-1 |
SR-05000001440-2 |
Famotidine, British Pharmacopoeia (BP) Reference Standard |
Famotidine, European Pharmacopoeia (EP) Reference Standard |
Famotidine, United States Pharmacopeia (USP) Reference Standard |
3-(((2-guanidinothiazol-4-yl)methyl)thio)-N-sulfamoylpropanimidamide |
3-(2-guanidinothiazol-4-yl)methylsulfanyl-N-sulfamoyl-propanamidine |
Famotidine, Pharmaceutical Secondary Standard; Certified Reference Material |
3-(2-(Diaminomethyleneamino)-1,3-thiazol-4-yl)methylthio)-N- sulfamoylpropionamidine |
3-2-(diaminomethyleneamino thiazol-4-ylmethylthio-N-sulphamoyl propionamidine |
Famotidine for system suitability, European Pharmacopoeia (EP) Reference Standard |
N-(Aminosulfonyl)-3-2-(diaminomethylene)amino-4-thiazolylmethylthiopropanimidamide |
(1Z)-2-amino-4-{2-(2,2-diamino-1-azavinyl)(1,3-thiazol-4-yl)methylthio}-1-az abut-1-enesulfonamide |
3-({2-(Diaminomethylene)amino-1,3-thiazol-4-yl}methyl)sulfanyl-N-sulfamoylpropanimidamide" |
3-({2-(diaminomethylidene)amino-1,3-thiazol-4-yl}methyl)sulfanyl-N-sulfamoylpropanimidamide" |
Experimental Data
famotidine
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | 9.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
famotidine
Statistics Data
famotidine
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 9.000000000000000 | 1 | 1 |
Statistics Data Visualization
famotidine
