Compound Summary

ethosuximide
  Compound Information
 ethosuximide

Compound Name:

ethosuximide

Compound CID:

3291

Synonyms:

ethosuximide

77-67-8

Zarontin

Etosuximida

2-Ethyl-2-methylsuccinimide

More...

Iupac Name:

3-ethyl-3-methylpyrrolidine-2,5-dione

InChI:

InChI=1S/C7H11NO2/c1-3-7(2)4-5(9)8-6(7)10/h3-4H2,1-2H3,(H,8,9,10)

InChIKey:

HAPOVYFOVVWLRS-UHFFFAOYSA-N

Canonical Smiles:

CCC1(CC(=O)NC1=O)C

Isomeric Smiles:

CCC1(CC(=O)NC1=O)C

Molecular Weight:

141.17

Molecular Formula:

C7H11NO2

  Compound Structure
 2D Structure:
 3D Structure:
  Computed Properties
 ethosuximide

Molecular Weight:

141.17

Molecular Formula:

C7H11NO2

Hydrogen Bond Donor Count:

1

Hydrogen Bond Acceptor Count:

2

Rotatable Bond Count:

1

Heavy Atom Count:

10

Complexity:

188

  Synonyms
 ethosuximide

ethosuximide ethosuximide

ethosuximide

77-67-8

Zarontin

Etosuximida

2-Ethyl-2-methylsuccinimide

Ethosuxide

Ethosuccimide

Ethosuccinimide

Etosuximid

Petnidan

Suxinutin

Atysmal

Emeside

Ethymal

Suxilep

3-Ethyl-3-methylpyrrolidine-2,5-dione

Pentinimid

Peptinimid

Petinimid

Pyknolepsinum

Succimitin

Zaraondan

Capitus

Mesentol

Pemalin

Simatin

Succimal

Suximal

Thetamid

Zarodan

Zarondan

Zartalin

Asamid

Etomal

Pemal

Ronton

Suxin

Aethosuximide

Piknolepsin

Thilopemal

Epileo Petit MAL

Zarondan-Saft

Simatin(E)

Ethosuximidum

3-Methyl-3-ethylsuccinimide

3-Ethyl-3-methyl-2,5-pyrrolidinedione

2-Methyl-2-ethylsuccinimide

2,5-Pyrrolidinedione, 3-ethyl-3-methyl-

CI-366

Succinimide, 2-ethyl-2-methyl-

3-Ethyl-3-methylsuccinimide

PM 671

PM-671

CN-10,395

3-Methyl-3-ethylpyrrolidine-2,5-dione

alpha-Ethyl-alpha-methylsuccinimide

alpha-Methyl-alpha-ethylsuccinimide

gamma-Methyl-gamma-ethyl-succinimide

C.I. 366

H 940

H-490

Cl 366

(+-)-2-Ethyl-2-methylsuccinimide

CN-10395

gamma-ethyl-gamma-methyl-succinimide

NSC-64013

3-Ethyl-3-methylpyrroline-2,5-dione

CHEMBL696

.alpha.-Ethyl-.alpha.-methylsuccinimide

3-ethyl-3-methyl-pyrrolidine-2,5-dione

CHEBI:4887

Aethosuccimidum

Etosuximide

NSC64013

MFCD00072123

.gamma.-Methyl-.gamma.-ethylsuccinimide

Etosuccimide

Etosuccimide DCIT

Aethosuximide German

DSSTox_CID_3019

N-Ethyl methylsuccinimide

DSSTox_RID_76832

DSSTox_GSID_23019

Ethosuximidum INN-Latin

Etosuximida INN-Spanish

Pyknole.psi.num

Piknole.psi.n

Zarontin (TN)

HSDB 1119

SR-01000075863

EINECS 201-048-7

CI 366

NSC 64013

BRN 0117054

CAS-77-67-8

NCGC00016320-01

Prestwick_611

Ethosuximide USAN:USP:INN:BAN:JAN

Spectrum_001385

Prestwick0_000165

Prestwick1_000165

Prestwick2_000165

Prestwick3_000165

Spectrum2_001483

Spectrum3_000944

Spectrum4_001051

Spectrum5_001073

E0746

(.+/-.)-Ethosuximide

2, 3-ethyl-3-methyl-

E 7138

NCIOpen2_000014

Lopac0_000532

SCHEMBL34212

BSPBio_000029

KBioGR_001342

KBioSS_001865

5-21-09-00595 (Beilstein Handbook Reference)

DivK1c_000218

SPECTRUM1502196

2,5-Pyrrolidinedione, 3-ethyl-3-methyl-, (+-)-

SPBio_001465

SPBio_001950

BPBio1_000033

GTPL7182

WLN: T5VMVTJ D2 D1

DTXSID7023019

SCHEMBL20541518

Ethosuximide (JP17/USP/INN)

Ethosuximide, analytical standard

HMS500K20

KBio1_000218

KBio2_001865

KBio2_004433

KBio2_007001

KBio3_002008

AOB5337

NINDS_000218

HMS1568B11

HMS1921L14

HMS2092D20

HMS2095B11

HMS3261L05

HMS3712B11

HMS3885D12

Pharmakon1600-01502196

HY-B1378

Ethosuximide 1.0 mg/ml in Methanol

Tox21_110370

Tox21_500532

(+/-)-2-ethyl-2-methylsuccinimide

BDBM50240424

CCG-39217

NSC758192

s4626

3-ethyl-3-methylazolidine-2,5-dione

AKOS005261742

Tox21_110370_1

CS-7976

DB00593

LP00532

MCULE-4034034545

NSC-758192

SDCCGSBI-0050515.P004

.alpha.-Methyl-.alpha.-ethylsuccinimide

IDI1_000218

NCGC00015418-02

NCGC00015418-03

NCGC00015418-04

NCGC00015418-05

NCGC00015418-06

NCGC00015418-08

NCGC00015418-09

NCGC00015418-15

NCGC00093923-01

NCGC00093923-02

NCGC00093923-03

NCGC00093923-04

NCGC00261217-01

3-Ethyl-3-methyl-2, 5-pyrrolidinedione

AS-16859

SBI-0050515.P003

2, 5-Pyrrolidinedione, 3-ethyl-3-methyl-

AB00052288

EU-0100532

FT-0668060

FT-0668061

ST51037248

C07505

D00539

D70258

AB00052288_04

zarontin3-Ethyl-3-methyl-pyrrolidine-2,5-dione

Q421567

SR-01000075863-1

SR-01000075863-3

SR-01000075863-5

W-109273

3-Ethyl-3-methyl-pyrrolidine-2,5-dione(Ethosuximide)

BRD-A99633051-001-04-7

BRD-A99633051-001-05-4

3-Ethyl-3-methyl-pyrrolidine-2,5-dione (ethosuximide)

Z2379802739

3-ethyl-5-hydroxy-3-methyl-3,4-dihydro-2H-pyrrol-2-one

4-ethyl-5-hydroxy-4-methyl-3,4-dihydro-2H-pyrrol-2-one

Ethosuximide, European Pharmacopoeia (EP) Reference Standard

Ethosuximide, United States Pharmacopeia (USP) Reference Standard

Ethosuximide solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material
  Experimental Data
 ethosuximide

Species Dose Unit Control(Avg days) Treatment(Avg days) Avg/Med Lifespan Change(%) Control(Max days) Treatment(Max days) Max Lifespan Change(%) Significant Strain Gender PubMed Avg/Med Lifespan Change tab
Caenorhabditis elegans 5.000000000000000 mM Unclear N2 33683565
Caenorhabditis elegans 50.000000000000000 mM Unclear N2 33683565
Caenorhabditis elegans 70.000000000000000 mM Unclear N2 33683565
Caenorhabditis elegans 50.000000000000000 mM Unclear N2 33683565
Caenorhabditis elegans 5.000000000000000 mM Unclear N2 33683565
Caenorhabditis elegans 50.000000000000000 mM Unclear N2 33683565
Caenorhabditis elegans 30.000000000000000 mM Unclear N2 33683565
Caenorhabditis elegans 10.000000000000000 mM Unclear N2 33683565
Caenorhabditis elegans 10.000000000000000 mM Unclear N2 33683565
Caenorhabditis elegans 80.000000000000000 mM Unclear N2 33683565
Caenorhabditis elegans 30.000000000000000 mM Unclear N2 33683565
Caenorhabditis elegans 5.000000000000000 mM Unclear N2 33683565
Caenorhabditis elegans 10.000000000000000 mM Unclear N2 33683565
Caenorhabditis elegans 2.000000000000000 mg/mL Unclear N2 33683565
Caenorhabditis elegans 85.000000000000000 mM Unclear N2 33683565
Caenorhabditis elegans 4.000000000000000 mg/mL 17.000000000000000 22.000000000000000 S N2 33683565 Active
Caenorhabditis elegans 4.000000000000000 mg/mL 14.000000000000000 -2.000000000000000 S N2 33683565 Active
Caenorhabditis elegans 2.000000000000000 mg/mL 13.000000000000000 24.000000000000000 S N2 33683565 Active
Caenorhabditis elegans 2.000000000000000 mg/mL 16.700000000000000 19.600000000000000 17.000000000000000 23.300000000000000 28.500000000000000 22.000000000000000 S N2 15653505 Active
Caenorhabditis elegans 32.000000000000000 S N2 16872777 Active
Caenorhabditis elegans 33.000000000000000 umol/L 3.000000000000000 NS N2 24134630 Inactive
Caenorhabditis elegans 4.000000000000000 mg/mL 35.000000000000000 37.000000000000000 S N2 33683565 Active
Caenorhabditis elegans 2.000000000000000 mg/mL 16.700000000000000 18.900000000000000 13.000000000000000 23.300000000000000 28.900000000000000 24.000000000000000 S N2 15653505 Active
  Experimental Data Visualization
 ethosuximide

  Statistics Data
 ethosuximide

Species Avg/Med Lifespan Change(%) Max Lifespan Change(%) Count Reference Count Data point
Caenorhabditis elegans 35.000000000000000 37.000000000000000 4 23
  Statistics Data Visualization
 ethosuximide

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