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Compound Summary

doxifluridine

Compound Information

doxifluridine

Compound Name:	doxifluridine
Compound CID:	18343
Synonyms:	doxifluridine 5-Deoxy-5-fluorouridine" 5-fluoro-5-deoxyuridine Furtulon 3094-09-5 More...
Iupac Name:	1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoropyrimidine-2,4-dione
InChI:	InChI=1S/C9H11FN2O5/c1-3-5(13)6(14)8(17-3)12-2-4(10)7(15)11-9(12)16/h2-3,5-6,8,13-14H,1H3,(H,11,15,16)/t3-,5-,6-,8-/m1/s1
InChIKey:	ZWAOHEXOSAUJHY-ZIYNGMLESA-N
Canonical Smiles:	CC1C(C(C(O1)N2C=C(C(=O)NC2=O)F)O)O
Isomeric Smiles:	C[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=C(C(=O)NC2=O)F)O)O
Molecular Weight:	246.19
Molecular Formula:	C9H11FN2O5

Compound Structure

2D Structure:

3D Structure:

Computed Properties

doxifluridine

Molecular Weight:	246.19
Molecular Formula:	C9H11FN2O5
Hydrogen Bond Donor Count:	3
Hydrogen Bond Acceptor Count:	6
Rotatable Bond Count:	1
Heavy Atom Count:	17
Complexity:	399

Synonyms

doxifluridine

doxifluridine	doxifluridine
doxifluridine	5-Deoxy-5-fluorouridine"
5-fluoro-5-deoxyuridine	Furtulon
3094-09-5	5-Dfur"
Uridine, 5-deoxy-5-fluoro-	Doxifluridina
Doxifluridinum	Ro 21-9738
Ro 219738	5dFUrd
1-(beta-D-5-Desoxyribofuranoxyl)-5-fluoruracil	UNII-V1JK16Y2JP
CHEMBL1130	V1JK16Y2JP
Capecitabine related compound b	1-((2R,3R,4S,5R)-3,4-dihydroxy-5-methyltetrahydrofuran-2-yl)-5-fluoropyrimidine-2,4(1H,3H)-dione
CHEBI:31521	NCGC00093926-03
Flutron	Doxifluridine (5-Fluoro-5-deoxyuridine)
DSSTox_CID_2967	5FDUR
DSSTox_RID_76809	DSSTox_GSID_22967
5-Doxifluridine"	5-dFUrd
Furtulon (TN)	1-(2R,3R,4S,5R)-3,4-dihydroxy-5-methyl-tetrahydrofuran-2-yl-5-fluoro-pyrimidine-2,4-dione
SMR000326811	CAS-3094-09-5
Uridine-5-deoxy-5-fluoro-	SR-01000075886
Doxifluridine INN:JAN	5-DFUR
Doxifluridinum INN-Latin	Doxifluridina INN-Spanish
MFCD00866530	EINECS 221-440-1
5-Deoxy-5-fluorouridine	5-Fluoro-5`-deoxyuridine
SCHEMBL8094	Doxifluridine (JP17/INN)
Lopac0_000537	MLS001332579
MLS001332580	MLS002172440
MLS002207077	DTXSID2022967
HMS2090C22	HMS2231I05
HMS3261L15	ACN-S003358
AMC 0101	AMY13408
HY-B0021	ZINC1319177
Tox21_111231	Tox21_500537
BDBM50132295	s2045
CAPECITABINE IMPURITY B (USP)	AKOS015852921
AKOS015896821	Tox21_111231_1
CCG-204627	CS-1270
DB12947	KS-5065
LP00537	NSC 758890
SDCCGSBI-0050520.P002	1-(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl-5-fluoropyrimidine-2,4-dione
NCGC00093926-01	NCGC00093926-02
NCGC00093926-05	NCGC00093926-11
NCGC00261222-01	Ro-21-9738
SRI-11552-08	SRI-11552_09
5-Deoxy-5-Fluorouridine (5-Dfur)	RO-219738
EU-0100537	D01309
F 8791	15185-EP2272827A1
15185-EP2275420A1	15185-EP2295055A2
15185-EP2295416A2	15185-EP2295426A1
15185-EP2295427A1	15185-EP2298748A2
15185-EP2298764A1	15185-EP2298765A1
15185-EP2298768A1	15185-EP2298778A1
15185-EP2305642A2	15185-EP2311453A1
15185-EP2311808A1	15185-EP2311829A1
15185-EP2316832A1	15185-EP2316833A1
094F095	Q1253473
SR-01000075886-1	SR-01000075886-5
5-DFUR (5-Deoxy-5-fluorouridine, Doxifluridine)	BRD-K58262659-001-09-7
Capecitabine impurity B, European Pharmacopoeia (EP) Reference Standard	Capecitabine Related Compound B, United States Pharmacopeia (USP) Reference Standard
1-((2R,3R,4S,5R)-3,4-dihydroxy-5-methyl-tetrahydrofuran-2-yl)-5-fluoropyrimidine-2,4(1H,3H)-dione	1-((2R,5R)-3,4-Dihydroxy-5-methyl-tetrahydro-furan-2-yl)-5-fluoro-1H-pyrimidine-2,4-dione
1-((4S,2R,3R,5R)-3,4-Dihydroxy-5-methyloxolan-2-yl)-5-fluoro-1,3-dihydropyrimidine-2,4-dione	1-(5-Deoxy-beta-D-ribofuranosyl)-5-fluoropyrimidine-2,4(1H,3H)-dione (5-Deoxy-5-fluorouridine)"

Experimental Data

doxifluridine

Species	Dose	Unit	Control(Avg days)	Treatment(Avg days)	Avg/Med Lifespan Change(%)	Control(Max days)	Treatment(Max days)	Max Lifespan Change(%)	Significant	Strain	Gender	PubMed	Avg/Med Lifespan Change tab
Caenorhabditis elegans	33.000000000000000	umol/L			7.000000000000000				NS	N2		24134630	Inactive

Experimental Data Visualization

doxifluridine

Statistics Data

doxifluridine

Species	Avg/Med Lifespan Change(%)	Max Lifespan Change(%)	Count Reference	Count Data point
Caenorhabditis elegans	7.000000000000000		1	1

Statistics Data Visualization

doxifluridine

Compound Name:

doxifluridine

Compound CID:

18343

Synonyms:

doxifluridine 5-Deoxy-5-fluorouridine" 5-fluoro-5-deoxyuridine Furtulon 3094-09-5 More...

Iupac Name:

1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoropyrimidine-2,4-dione

InChI:

InChI=1S/C9H11FN2O5/c1-3-5(13)6(14)8(17-3)12-2-4(10)7(15)11-9(12)16/h2-3,5-6,8,13-14H,1H3,(H,11,15,16)/t3-,5-,6-,8-/m1/s1

InChIKey:

ZWAOHEXOSAUJHY-ZIYNGMLESA-N

Canonical Smiles:

CC1C(C(C(O1)N2C=C(C(=O)NC2=O)F)O)O

Isomeric Smiles:

C[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=C(C(=O)NC2=O)F)O)O

Molecular Weight:

246.19

Molecular Formula:

C9H11FN2O5

Molecular Weight:

246.19

Molecular Formula:

C9H11FN2O5

Hydrogen Bond Donor Count:

3

Hydrogen Bond Acceptor Count:

6

Rotatable Bond Count:

1

Heavy Atom Count:

17

Complexity:

399

doxifluridine

5-Deoxy-5-fluorouridine"

5-fluoro-5-deoxyuridine

Furtulon

3094-09-5

5-Dfur"

Uridine, 5-deoxy-5-fluoro-

Doxifluridina

Doxifluridinum

Ro 21-9738

Ro 219738

5dFUrd

1-(beta-D-5-Desoxyribofuranoxyl)-5-fluoruracil

UNII-V1JK16Y2JP

CHEMBL1130

V1JK16Y2JP

Capecitabine related compound b

1-((2R,3R,4S,5R)-3,4-dihydroxy-5-methyltetrahydrofuran-2-yl)-5-fluoropyrimidine-2,4(1H,3H)-dione

CHEBI:31521

NCGC00093926-03

Flutron

Doxifluridine (5-Fluoro-5-deoxyuridine)

DSSTox_CID_2967

5FDUR

DSSTox_RID_76809

DSSTox_GSID_22967

5-Doxifluridine"

5-dFUrd

Furtulon (TN)

1-(2R,3R,4S,5R)-3,4-dihydroxy-5-methyl-tetrahydrofuran-2-yl-5-fluoro-pyrimidine-2,4-dione

SMR000326811

CAS-3094-09-5

Uridine-5-deoxy-5-fluoro-

SR-01000075886

Doxifluridine INN:JAN

5-DFUR

Doxifluridinum INN-Latin

Doxifluridina INN-Spanish

MFCD00866530

EINECS 221-440-1

5-Deoxy-5-fluorouridine

5-Fluoro-5`-deoxyuridine

SCHEMBL8094

Doxifluridine (JP17/INN)

Lopac0_000537

MLS001332579

doxifluridine

5-Deoxy-5-fluorouridine"

5-fluoro-5-deoxyuridine

Furtulon

3094-09-5

More...