Compound Summary

domperidone
  Compound Information
 domperidone

Compound Name:

domperidone

Compound CID:

3151

Synonyms:

domperidone

57808-66-9

Motilium

Nauzelin

Domperidonum

More...

Iupac Name:

6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H-benzimidazol-2-one

InChI:

InChI=1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30)

InChIKey:

FGXWKSZFVQUSTL-UHFFFAOYSA-N

Canonical Smiles:

C1CN(CCC1N2C3=C(C=C(C=C3)Cl)NC2=O)CCCN4C5=CC=CC=C5NC4=O

Isomeric Smiles:

C1CN(CCC1N2C3=C(C=C(C=C3)Cl)NC2=O)CCCN4C5=CC=CC=C5NC4=O

Molecular Weight:

425.9

Molecular Formula:

C22H24ClN5O2

  Compound Structure
 2D Structure:
 3D Structure:
  Computed Properties
 domperidone

Molecular Weight:

425.9

Molecular Formula:

C22H24ClN5O2

Hydrogen Bond Donor Count:

2

Hydrogen Bond Acceptor Count:

3

Rotatable Bond Count:

5

Heavy Atom Count:

30

Complexity:

655

  Synonyms
 domperidone

domperidone domperidone

domperidone

57808-66-9

Motilium

Nauzelin

Domperidonum

Domperidona

4-(5-Chloro-2-oxo-1-benzimidazolinyl)-1-3-(2-oxobenzimidazolinyl)propylpiperidine

R-33812

R 33,812

NSC299589

Domperidone (Motilium)

5-Chloro-1-(1-(3-(2-oxo-1-benzimidazolinyl)propyl)-4-piperidyl)-2-benzimidazolinone

R33812

UNII-5587267Z69

KW 5338

6-chloro-3-1-3-(2-oxo-3H-benzimidazol-1-yl)propylpiperidin-4-yl-1H-benzimidazol-2-one

MLS000069343

CHEMBL219916

CHEBI:31515

MFCD00069256

NSC 299589

NSC-299589

5-Chloro-1-1-3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl-4-piperidinyl-1,3-dihydro-2H-benzimidazol-2-one

5-chloro-1-{1-3-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)propylpiperidin-4-yl}-1,3-dihydro-2H-benzimidazol-2-one

Motinorm

Costi

5-Chloro-1-1-3-(2-oxo-1-benzimidazolinyl)propyl-4-piperidyl-2-benzimidazolinone

DSSTox_CID_25116

DSSTox_RID_80682

DSSTox_GSID_45116

1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzodimidazol-1-yl)piperidin-1-yl)propyl)-1H-benzodimidazol-2(3H)-one

5-chloro-1-(1-(3-(2-oxo-2,3-dihydro-1H-benzodimidazol-1-yl)propyl)piperidin-4-yl)-1H-benzodimidazol-2(3H)-one

5-chloro-1-(1-(3-(2-oxo-2,3-dihydrobenzodimidazol-1-yl)propyl)piperidin-4-yl)-1H-benzodimidazol-2(3H)-one

5-chloro-1-{1-3-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl)propylpiperidin-4-yl}-2,3-dihydro-1H-1,3-benzodiazol-2-one

5-Chloro-1-{1-3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one

Domperidonum INN-Latin

Domperidona INN-Spanish

5587267Z69

Motillium

Motilium (TN)

SMR000326802

CAS-57808-66-9

KW-5338

Lopac-D-122

SR-01000003002

EINECS 260-968-7

BRN 0903774

Nauzelin OD

Domperidone,(S)

5-chloro-1-{1-3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl-4-piperidinyl}-1,3-dihydro-2H-benzimidazol-2-one

Domperidone USAN:INN:BAN:JAN

Prestwick_794

NCI299589

HS-0067

Spectrum_000391

Opera_ID_616

SpecPlus_000825

Prestwick0_000461

Prestwick1_000461

Prestwick2_000461

Prestwick3_000461

Spectrum4_000087

D-122

Biomol-NT_000022

Domperidone - pharma grade

NCIStruc1_001686

NCIStruc2_001819

Lopac0_000427

SCHEMBL43729

BSPBio_002350

GTPL965

KBioGR_000354

KBioSS_000871

2H-Benzimidazol-2-one, 5-chloro-1-(1-(3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl)-4-piperidinyl)-1,3-dihydro-

5-24-02-00402 (Beilstein Handbook Reference)

MLS000859942

MLS001306482

MLS002222324

DivK1c_006921

SPECTRUM2300212

SPBio_002501

BPBio1_000620

BPBio1_001185

DTXSID1045116

Domperidone (JP17/USAN/INN)

KBio1_001865

KBio2_000871

KBio2_003439

KBio2_006007

HMS1922N04

HMS2089C14

HMS2093N22

HMS2096C21

HMS2230N18

HMS3261E16

HMS3269O13

HMS3370L03

HMS3413F15

HMS3656M21

HMS3677F15

HMS3713C21

HMS3884N19

Pharmakon1600-02300212

BCP28265

Domperidone 1.0 mg/ml in Methanol

EBD46624

HY-B0411

ZINC4175569

Tox21_110056

Tox21_500427

BBL028136

BDBM50241107

CCG-37870

CD0227

NCGC00014670

NSC759575

s2461

STK622843

AKOS005555858

Tox21_110056_1

AC-2037

DB01184

Domperidone, powder, >=98% (HPLC)

LP00427

MCULE-4430288884

NSC 759575

NSC-759575

SDCCGSBI-0050412.P004

NCGC00014670-01

NCGC00014670-02

NCGC00014670-03

NCGC00014670-04

NCGC00014670-05

NCGC00014670-06

NCGC00014670-07

NCGC00014670-08

NCGC00014670-09

NCGC00014670-10

NCGC00014670-11

NCGC00014670-12

NCGC00014670-13

NCGC00014670-14

NCGC00014670-16

NCGC00014670-17

NCGC00014670-28

NCGC00015306-01

NCGC00021472-02

NCGC00021472-03

NCGC00021472-04

NCGC00021472-05

NCGC00021472-06

NCGC00021472-07

NCGC00021472-08

NCGC00097773-01

NCGC00261112-01

2H-Benzimidazol-2-one, 1,3-dihydro-5-chloro-1-(1-(3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl)-4-piperidinyl)-

5-chloro-1-(1-(3-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)propyl)-4-piperidinyl)-1,3-dihydro-2H-benzimidazol-2-one

5-chloro-1-(1-(3-(2-oxo-2,3-dihydro-1H-benzodimidazol-1-yl)propyl)piperidin-4-yl)-1,3-dihydro-2H-benzodimidazol-2-one

BD164379

NCI60_002512

SMR000058969

AB0110085

AB00052423

D4125

EU-0100427

FT-0625588

SW196931-3

C75710

D01745

AB00052423-06

AB00052423-07

AB00052423_08

AB00052423_09

808D669

A831618

L000230

Q424238

R 33812

SR-01000003002-2

SR-01000003002-4

SR-01000003002-7

W-105440

BRD-K38305202-001-02-6

BRD-K38305202-001-08-3

Domperidone, European Pharmacopoeia (EP) Reference Standard

5-Chloro-1-1-3-(2-oxo-1-benzimidazolyl)propyl-4-piperidylbenzimidazol-2-one

2H-Benzimidazol-2-one,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl-4-piperidinyl-1,3-dihydro-

5-Chloro-1-1-3-(2,3-dihydro-2-oxo -1H-benzimidazol-1-yl)propyl-4-piperidinyl-1,3-d ihydro-2H-benzimidazol-2-one

5-Chloro-1-1-3-(2-oxo-2,3-dihydro-1H-benzimidazol-1- yl)propylpiperidin-4-yl-1,3-dihydro-2H-benzimidazol-2-one

5-chloro-1-1-3-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)propylpiperidine-4-yl-1,3-dihydro-2H-benzimidazol-2-one;

5-chloro-1-{1-3(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl-4-piperidinyl}-1,3-dihydro-2H-benzimidazol-2-one

5-chloro-1-{1-3-(1,3-dihydro-2-oxo-2H-benzimidazol-1-yl)propyl-4-piperidinyl}-1,3-dihydro-2H-benzimidazol-2-one

5-Chloro-1-{1-3-(2-hydroxy-2,3-dihydro-benzoimidazol-1-yl)-propyl-piperidin-4-yl}-2,3-dihydro-1H-benzoimidazol-2-ol

5-Chloro-1-{1-3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(domperidone)

6-chloro-3-1-3-(2-oxo-3a,7a-dihydro-3H-benzimidazol-1-yl)propyl-4-piperidyl-3a,7a-dihydro-1H-benzimidazol-2-one

DOMPERIDONE5-Chloro-1-{1-3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one
  Experimental Data
 domperidone

Species Dose Unit Control(Avg days) Treatment(Avg days) Avg/Med Lifespan Change(%) Control(Max days) Treatment(Max days) Max Lifespan Change(%) Significant Strain Gender PubMed Avg/Med Lifespan Change tab
Caenorhabditis elegans 33.000000000000000 umol/L 6.000000000000000 NS N2 24134630 Inactive
  Experimental Data Visualization
 domperidone

  Statistics Data
 domperidone

Species Avg/Med Lifespan Change(%) Max Lifespan Change(%) Count Reference Count Data point
Caenorhabditis elegans 6.000000000000000 1 1
  Statistics Data Visualization
 domperidone

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