Compound Summary

dl-Thioctic acid
  Compound Information
 dl-Thioctic acid

Compound Name:

dl-Thioctic acid

Compound CID:

864

Synonyms:

dl-Thioctic acid

thioctic acid

alpha-Lipoic acid

1077-28-7

5-(1,2-Dithiolan-3-yl)pentanoic acid

More...

Iupac Name:

5-(dithiolan-3-yl)pentanoic acid

InChI:

InChI=1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)

InChIKey:

AGBQKNBQESQNJD-UHFFFAOYSA-N

Canonical Smiles:

C1CSSC1CCCCC(=O)O

Isomeric Smiles:

C1CSSC1CCCCC(=O)O

Molecular Weight:

206.3

Molecular Formula:

C8H14O2S2

  Compound Structure
 2D Structure:
 3D Structure:
  Computed Properties
 dl-Thioctic acid

Molecular Weight:

206.3

Molecular Formula:

C8H14O2S2

Hydrogen Bond Donor Count:

1

Hydrogen Bond Acceptor Count:

4

Rotatable Bond Count:

5

Heavy Atom Count:

12

Complexity:

150

  Synonyms
 dl-Thioctic acid

dl-Thioctic acid dl-Thioctic acid

dl-Thioctic acid

thioctic acid

alpha-Lipoic acid

1077-28-7

5-(1,2-Dithiolan-3-yl)pentanoic acid

lipoic acid

DL-alpha-Lipoic acid

1,2-dithiolane-3-pentanoic acid

alpha Lipoic Acid

Thioctacid

62-46-4

Biletan

6,8-Thioctic acid

6-Thioctic acid

Lipothion

dl-Lipoic acid

DL-6,8-Thioctic acid

5-(dithiolan-3-yl)pentanoic acid

Liposan

Thioctsan

Tioctacid

Rac-lipoate

6,8-Dithiooctanoic acid

alpha-Liponsaeure

DL-6-Thioctic acid

Thioctic acid dl-form

alpha-liponic acid

1,2-Dithiolane-3-valeric acid

Thioktsaeure

Tioctidasi

(RS)-Lipoic acid

5-(1,2-Dithiolan-3-yl)valeric acid

espa-lipon

5-(Dithiolan-3-yl)valeric acid

Acetate-replacing factor

6,8-Thiotic acid

Thioctansaeure

6-Thiotic acid

DL-1,2-Dithiolane 3-valeric acid

(+-)-Lipoic acid

Thioctsaeure

liponic acid

Thiooctic acid

a-lipoic acid

DL-.alpha.-Lipoic acid

(+/-)-1,2-Dithiolane-3-pentanoic acid

DL-1,2-Dithiolane-3-valeric acid

lipoate

MFCD00005474

NSC 90788

Lipoic acid, alpha

NSC 628502

(RS)-thioctic acid

(+-)-1,2-Dithiolane-3-pentanoic acid

.alpha.-Liponic acid

CHEBI:16494

Lip(S2)

DL-1,2-Dithiolan-3-valeriansaeure

(.+-.)-Lipoic acid

1,2-DITHIOLANE-3-VALERIC ACID, (+-)-

(RS)-.alpha.-Lipoic acid

5-3-(1,2-dithiolanyl)pentanoic acid

CHEMBL33864

(.+-.)-.alpha.-Lipoic acid

NSC90788

NSC-90788

NCGC00016032-06

DSSTox_CID_5508

Protogen A

(+/-)-alpha-Lipoic acid

DSSTox_RID_77816

DSSTox_GSID_25508

Berlition

Thiogamma

(R)-(+)-alpha-Lipoic acid;R-(+)-Thioctic acid

L-Thioctic acid

Thioktsaeure German

biomolipon

duralipon

Alipure

AlphaLipogamma

Thiotacid

biomo lipon

espa lipon

Alpha Lipogamma

Alpha-Lipogamma

Pyruvate oxidation factor

DL-Thiocticacid

Pleomix Alpha

Thioctacide T

Verla Lipon

AlphaLipon Stada

.alpha.-Lipoic acid

Alpha Lippon AL

alpha-Liponsaeure German

Alpha Lipon Stada

Alpha-Lipon Stada

5-(1,2)Dithiolan-3-yl-pentanoic acid

5-1,2Dithiolan-3-yl-pentanoic acid

Liponsaureratiopharm

alpha-lipon 300

SMR000058198

CAS-1077-28-7

Liponsaure-ratiopharm

(+-)-Thioctic acid

alpha Liponsaure von ct

Tioctidasi acetate replacing factor

SR-01000737460

(RS)-alpha-Lipoic acid

EINECS 200-534-6

EINECS 214-071-2

(+-)-alpha-lipoic acid

BRN 0081853

BRN 0122410

Alpha Lipoic

Alphalipoic-acid

DL-1,2-Dithiolan-3-valeriansaeure German

Thioctic acid INN:BAN:JAN

HSDB 7818

alpha-lipoic-acid

D,L-Lipoic acid

Thiotomin (TN)

DL-a-Lipoic acid

D,L-Thioctic acid

lipoic acid (LA)

LIPOIC-ACID

Thioctic acid (JAN)

()-alpha-Lipoic acid

Spectrum_001618

5-(1,2-dithiolan-3-yl)-pentanoate

Thioctic acid, dl-form

R-(+)-alpaLipoic acid

1,2-Dithiolane-3-pentanoic acid, (+-)-

Spectrum2_001605

Spectrum3_001188

Spectrum4_000217

Spectrum5_001298

(S)-(-)-Thiocticacid

(+/-)-a-Lipoic acid

cid_864

(.+-.)-Thioctic acid

Lipoic acid, alpha NF

ACMC-209ug2

bmse000542

Epitope ID:150922

(+/-)-?-Lipoic acid

(.+/-.)-Lipoic acid

ACMC-1BU44

SCHEMBL51065

BSPBio_002835

DL-Thioctic acid (oxidized)

KBioGR_000853

KBioSS_002098

5-19-07-00237 (Beilstein Handbook Reference)

MLS000069736

MLS001332379

MLS001332380

MLS002153365

DivK1c_000912

SPECTRUM1503941

(R)-(+)- a-Lipoic acid

SPBio_001609

DTXSID7025508

BDBM10515

HMS502N14

KBio1_000912

KBio2_002098

KBio2_004666

KBio2_007234

KBio3_002335

NINDS_000912

thioctic acid (alpha-lipoic acid)

HMS1922M22

HMS3649H08

HMS3885I16

Pharmakon1600-01503941

ACT14091

ALBB-030318

BCP13221

BCP14048

BCP18944

HY-N0492

Tox21_110285

Tox21_201808

Tox21_303092

AC7875

BBL013878

CCG-39063

dl-1,2-Dithiolane-3-pentanoic acid

NSC628502

NSC758651

s3996

SBB003484

STK801969

()-1,2-Dithiolane-3-pentanoic acid

AKOS000121582

AKOS016339634

Tox21_110285_1

AB09328

AM84329

CS-4370

EBD2203019

KS-1322

LS40210

MCULE-1034910084

NSC-628502

NSC-758651

SB49517

IDI1_000912

DL-THIOCTIC ACID (OXIDIZED) 25G

NCGC00016032-02

NCGC00016032-03

NCGC00016032-04

NCGC00016032-05

NCGC00016032-07

NCGC00016032-08

NCGC00016032-09

NCGC00016032-11

NCGC00016032-14

NCGC00090872-01

NCGC00090872-02

NCGC00090872-03

NCGC00090872-04

NCGC00090872-05

NCGC00256970-01

NCGC00259357-01

(+/-)-alpha-Lipoic acid, >=98.0%

AC-22673

BP-31070

NCI60_042014

O217

R)-(+)-|A-Lipoic acid OOEthyAoEthAEa

ST073359

SY010902

(R)-(+)-(c) paragraph sign-Lipoic acid

SBI-0051871.P002

5-(1,2-Dithiolan-3-yl)pentanoic acid #

AB0010770

DB-050522

( inverted exclamation markA)-a-Lipoic acid

1,2-Dithiolane-3-pentanoic acid, (+/-)-

1,2-Dithiolane-3-valeric acid, (.+-.)-

FT-0622068

FT-0625429

FT-0670812

FT-0670813

L0058

1,2-Dithiolane-3-pentanoic acid, (.+-.)-

1,2-Dithiolane-3-valeric acid, (.+/-.)-

1,2-Dithiolane-3-pentanoic acid, (.+/-.)-

3049-EP2316827A1

C00725

D00086

J10446

AB00052393_09

(+/-)?-?1,2-?Dithiolane-?3-?Pentanoic Acid

A801751

Q312229

1,2-Dithiolane-3-pentanoic acid, (+-)- (9CI)

J-002007

J-520421

SR-01000737460-2

SR-01000737460-6

F2191-0208

Thioctic acid, European Pharmacopoeia (EP) Reference Standard

(+/-)-alpha-Lipoic acid, BioReagent, cell culture tested, >=99%

(+/-)-alpha-Lipoic acid, synthetic, >=99% (titration), powder

Alpha Lipoic Acid, United States Pharmacopeia (USP) Reference Standard

(R)-(+)-1,2-Dithiolane-3-pentanoic acid; R-(+)-Thioctic acid; R-(+)-alpha-Lipoic acid

AfAEA centa notA inverted exclamation markAfasAA|AfAEAdaggeratrade mark?-Lipoic Acid

Thioctic acid containing impurity B, European Pharmacopoeia (EP) Reference Standard

Thioctic acid for system suitability, European Pharmacopoeia (EP) Reference Standard

Thioctic Acid;1,2-Dithiolane-3-pentanoic acid;5-(1,2-Dithiolan-3-yl)valeric acid

  Experimental Data
 dl-Thioctic acid

Species Dose Unit Control(Avg days) Treatment(Avg days) Avg/Med Lifespan Change(%) Control(Max days) Treatment(Max days) Max Lifespan Change(%) Significant Strain Gender PubMed Avg/Med Lifespan Change tab
Rattus norvegicus 1.500000000000000 g/kg NS 18486188 Inactive
Caenorhabditis elegans 1.000000000000000 mM Unclear N2 33683565
Caenorhabditis elegans 100.000000000000000 umol/L Unclear N2 33683565
Caenorhabditis elegans 50.000000000000000 umol/L Unclear N2 33683565
Caenorhabditis elegans 50.000000000000000 umol/L -3.880000000000000 Unclear N2 33683565
Caenorhabditis elegans 500.000000000000000 umol/L Unclear N2 33683565
Caenorhabditis elegans 5.000000000000000 mM -29.280000000000000 Unclear N2 33683565
Caenorhabditis elegans 200.000000000000000 umol/L 6.760000000000000 Unclear N2 33683565
Caenorhabditis elegans 47.000000000000000 umol/L Unclear N2 33683565
Caenorhabditis elegans 10.000000000000000 umol/L Unclear N2 33683565
Caenorhabditis elegans 100.000000000000000 umol/L 9.630000000000000 Unclear N2 33683565
Caenorhabditis elegans 233.000000000000000 umol/L Unclear N2 33683565
Drosophila melanogaster 0.500000000000000 mM 36.000000000000000 40.000000000000000 0.110000000000000 S w1118 FEMALES 32648369 Active
Drosophila melanogaster 0.500000000000000 mM 43.000000000000000 48.000000000000000 0.120000000000000 S Canton-S FEMALES 32648369 Active
Drosophila melanogaster 0.500000000000000 mM 36.000000000000000 46.000000000000000 0.280000000000000 S Canton-S FEMALES 32648369 Active
Caenorhabditis elegans 1.000000000000000 mM 15.000000000000000 17.000000000000000 0.130000000000000 S N2 18755260 Active
Caenorhabditis elegans 200.000000000000000 umol/L 14.000000000000000 14.000000000000000 0.000000000000000 NS N2 18755260 Inactive
Caenorhabditis elegans 1.000000000000000 mM 15.000000000000000 17.000000000000000 0.130000000000000 NS N2 18755260 Inactive
Caenorhabditis elegans 5.000000000000000 mM 14.000000000000000 11.000000000000000 -0.210000000000000 S N2 18755260 Inactive
Caenorhabditis elegans 100.000000000000000 umol/L 15.000000000000000 16.000000000000000 0.070000000000000 NS N2 18755260 Inactive
Caenorhabditis elegans 1.000000000000000 mM 14.000000000000000 16.000000000000000 0.140000000000000 S N2 18755260 Active
Caenorhabditis elegans 25.000000000000000 umol/L 24.200000000000000 14.300000000000000 S N2 33683565 Active
Caenorhabditis elegans 1.000000000000000 mM 11.000000000000000 16.000000000000000 0.450000000000000 S N2 18755260 Active
Caenorhabditis elegans 50.000000000000000 umol/L 15.000000000000000 16.000000000000000 0.070000000000000 NS N2 18755260 Inactive
Caenorhabditis elegans 1.000000000000000 mM 14.000000000000000 18.000000000000000 0.290000000000000 S N2 18755260 Active
  Experimental Data Visualization
 dl-Thioctic acid

  Statistics Data
 dl-Thioctic acid

Species Avg/Med Lifespan Change(%) Max Lifespan Change(%) Count Reference Count Data point
Caenorhabditis elegans 24.200000000000000 14.300000000000000 2 21
Drosophila melanogaster 0.280000000000000 1 3
Rattus norvegicus 1 1
  Statistics Data Visualization
 dl-Thioctic acid

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