Compound Summary
disulfiram
Compound Information
disulfiram
Compound Name: | disulfiram |
Compound CID: | 3117 |
Synonyms: | disulfiram Tetraethylthiuram disulfide 97-77-8 Antabuse Bis(diethylthiocarbamoyl) disulfide More... |
Iupac Name: | diethylcarbamothioylsulfanyl N,N-diethylcarbamodithioate |
InChI: | InChI=1S/C10H20N2S4/c1-5-11(6-2)9(13)15-16-10(14)12(7-3)8-4/h5-8H2,1-4H3 |
InChIKey: | AUZONCFQVSMFAP-UHFFFAOYSA-N |
Canonical Smiles: | CCN(CC)C(=S)SSC(=S)N(CC)CC |
Isomeric Smiles: | CCN(CC)C(=S)SSC(=S)N(CC)CC |
Molecular Weight: | 296.5 |
Molecular Formula: | C10H20N2S4 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
disulfiram
Molecular Weight: | 296.5 |
Molecular Formula: | C10H20N2S4 |
Hydrogen Bond Donor Count: | 0 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 7 |
Heavy Atom Count: | 16 |
Complexity: | 201 |
Synonyms
disulfiram
| disulfiram | disulfiram |
|---|---|
disulfiram |
Tetraethylthiuram disulfide |
97-77-8 |
Antabuse |
Bis(diethylthiocarbamoyl) disulfide |
Antabus |
TETD |
Alcophobin |
Anticol |
Esperal |
Teturam |
Dicupral |
Exhorran |
Hoca |
Ethyldithiurame |
Abstensil |
Antaethyl |
Antietanol |
Antivitium |
Contralin |
Tetradine |
Tetraetil |
Teturamin |
Abstinil |
Abstinyl |
Antadix |
Antalcol |
Antetan |
Antetil |
Antietil |
Antikol |
Aversan |
Averzan |
Cronetal |
Krotenal |
Refusal |
Etabus |
Ethyl tuads |
Ethyl Thiram |
Ethyl Thiurad |
Ethyl Tuex |
Antaenyl |
Antaetil |
Antiaethan |
Contrapot |
Disulfan |
Disulfuram |
Ephorran |
Stopetyl |
Thiuranide |
Anteyl |
Bonibal |
Disetil |
Nocbin |
Tenurid |
Tenutex |
Tetidis |
Ekagom TEDS |
Ekagom TETDS |
Ethyldithiourame |
Noxal |
Anti-ethyl |
Alk-aubs |
Thiuram E |
TATD |
Soxinol TET |
Tetraethylthiram disulfide |
Ekagom DTET |
Accel TET |
Espenal |
Exhoran |
Sanceler TET-G |
Ro-sulfiram |
Tetraethylthiuram disulphide |
Tetraethylthiuram |
Tuads, ethyl |
Usaf B-33 |
Sanceler TET |
Tetraethylthioperoxydicarbonic diamide |
Stopaethyl |
Thireranide |
Antaethan |
Antethyl |
Tetradin |
Tillram |
Accel TET-R |
Ethyl Thiudad |
Dupon 4472 |
Tetraethylthiuran disulfide |
Anthethyl |
Disulphuram |
Dupont fungicide 4472 |
Hocakrotenalnci-C02959 |
Tetraethylthiram disulphide |
Bis(diethylthiocarbamyl) disulfide |
Tetraethylthiuram sulfide |
Thiuram disulfide, tetraethyl- |
N,N,N,N-Tetraethylthiuram disulfide |
Antabuse (TN) |
Bis(N,N-diethylthiocarbamoyl) disulfide |
C10H20N2S4 |
1,1-Dithiobis(N,N-diethylthioformamide) |
Disulfide, bis(diethylthiocarbamoyl) |
diethylcarbamothioylsulfanyl N,N-diethylcarbamodithioate |
ENT 27,340 |
NSC 190940 |
UNII-TR3MLJ1UAI |
Thioperoxydicarbonic diamide, tetraethyl- |
Bis(diethylthiocarbamoyl)disulphide |
NCI-C02959 |
TTS |
Bis(N,N-diethylthiocarbamoyl)disulphide |
N,N,N,N-Tetraethylthiuram disulphide |
Bis((diethylamino)thioxomethyl)disulphide |
Bis((diethylamino)thioxomethyl) disulfide |
Tetraethylthiuram disulfide;TETD |
Disulfiram (Antabuse) |
TR3MLJ1UAI |
N,N-diethyl(diethylcarbamothioyl)disulfanylcarbothioamide |
MFCD00009048 |
NSC-25953 |
Thioperoxydicarbonic diamide ((H2N)C(S)2S2), tetraethyl- |
CHEMBL964 |
MLS000069818 |
CHEBI:4659 |
Bis(diethylthiocarbamyoyl)disulfide |
1,1,1,1-disulfanediylbis(carbonothioylnitrilo)tetraethane |
NSC25953 |
Esperal France |
CAS-97-77-8 |
NCGC00016000-08 |
NCGC00016000-13 |
SMR000059171 |
Thioperoxydicarbonic diamide (((H2N)C(S))2S2), tetraethyl- |
DSSTox_CID_1322 |
Ancazide ET |
Akrochem TETD |
Perkacit TETD |
Ekaland TETD |
Perkait TETD |
DSSTox_RID_76082 |
DSSTox_GSID_21322 |
Ethyl Tuads Rodform |
Disulfiramum INN-Latin |
Thioperoxydicarbonic diamide ((H2N)C(S)2S2), N,N,N,N-tetraethyl- |
Disulfiramo INN-Spanish |
Bis(diethylamino)thioxomethyl disulfide |
CCRIS 582 |
1,1-DithiobisN,N-diethylthioformamide |
HSDB 3317 |
SR-01000076145 |
EINECS 202-607-8 |
NSC 25953 |
Disulfarim |
AI3-27340 |
Formamide, 1,1-dithiobis(N,N-diethylthio-" |
Thioperoxydicarbonic diamide (((H2N)C(S))2S2), N,N,N,N-tetraethyl- |
Disulfiram USP:INN:BAN:JAN |
Prestwick_182 |
Spectrum_001010 |
CPD000059171 |
Opera_ID_224 |
Prestwick0_000097 |
Prestwick1_000097 |
Prestwick2_000097 |
Prestwick3_000097 |
Spectrum2_001176 |
Spectrum3_000405 |
Spectrum4_000228 |
Spectrum5_001590 |
Lopac-T-1132 |
1,N-diethylthioformamide |
Formamide, 1,1-dithiobis(N,N-diethylthio)- |
UPCMLD-DP090 |
EC 202-607-8 |
T 1132 |
tetraethyl thiuram disulfide |
Tetraethyldithiuram disulfide |
Lopac0_001164 |
SCHEMBL27213 |
BSPBio_000054 |
BSPBio_001930 |
KBioGR_000895 |
KBioSS_001490 |
MLS000758264 |
MLS001076475 |
MLS001423963 |
ARONIS24121 |
SPECTRUM1500262 |
SPBio_001191 |
SPBio_001993 |
ACMC-209s92 |
BPBio1_000060 |
Disulfiram (JP17/USP/INN) |
GTPL7168 |
ORA102 |
DTXSID1021322 |
UPCMLD-DP090:001 |
KBio2_001490 |
KBio2_004058 |
KBio2_006626 |
KBio3_001150 |
ORA-102 |
Thioperoxydicarbonic diamide ((H2N)C(S))2S2, tetraethyl- |
HMS1568C16 |
HMS1920I16 |
HMS2051M17 |
HMS2090C18 |
HMS2091O22 |
HMS2095C16 |
HMS2230K06 |
HMS3263J09 |
HMS3371B21 |
HMS3393M17 |
HMS3655I19 |
HMS3712C16 |
HMS3867H13 |
Pharmakon1600-01500262 |
BCP07331 |
HY-B0240 |
ZINC1529266 |
bis-(diethyl-thiocarbamyl)-disulfide |
Tox21_110280 |
Tox21_300403 |
Tox21_400072 |
Tox21_501164 |
BDBM50058655 |
CCG-39549 |
DL-379 |
N,N,N-Tetraethylthiuram disulfide |
NSC756748 |
NSC800739 |
s1680 |
SBB058706 |
STL069539 |
1,1,1,1-{disulfanediylbis(thioxomethylene)-nitrilo}tetraethane |
AKOS000120201 |
Tox21_110280_1 |
AT13284 |
DB00822 |
HS-0057 |
LP01164 |
MCULE-1443050857 |
NC00063 |
NSC-756748 |
NSC-800739 |
SDCCGSBI-0051131.P005 |
WLN: 2N2 & YUS & S 2 |
NCGC00016000-01 |
NCGC00016000-02 |
NCGC00016000-03 |
NCGC00016000-04 |
NCGC00016000-05 |
NCGC00016000-06 |
NCGC00016000-07 |
NCGC00016000-09 |
NCGC00016000-10 |
NCGC00016000-11 |
NCGC00016000-12 |
NCGC00016000-14 |
NCGC00016000-15 |
NCGC00016000-18 |
NCGC00016000-29 |
NCGC00094423-01 |
NCGC00094423-02 |
NCGC00094423-03 |
NCGC00094423-05 |
NCGC00094423-06 |
NCGC00094423-07 |
NCGC00254447-01 |
NCGC00261849-01 |
N,N,N,N-tetraethylthiuram disulfide |
R531 |
Formamide,1-dithiobis(N,N-diethylthio)- |
SBI-0051131.P004 |
1,1-dithiobis(N,N-diethylthioformamide) |
DB-057683 |
AB00051976 |
B0479 |
EU-0101164 |
FT-0631502 |
FT-0667720 |
SW196492-4 |
Tetraethylthiuram disulfide, >=97.0% (S) |
W0030 |
C01692 |
D00131 |
S00294 |
AB00051976-20 |
AB00051976-21 |
AB00051976-23 |
AB00051976_22 |
AB00051976_25 |
A845750 |
Q409665 |
Q-201812 |
SR-01000076145-1 |
SR-01000076145-5 |
SR-01000076145-8 |
BRD-K32744045-001-05-6 |
BRD-K32744045-001-17-1 |
Z1522553469 |
Disulfiram, British Pharmacopoeia (BP) Reference Standard |
Disulfiram, European Pharmacopoeia (EP) Reference Standard |
1,1,1,1-disulfanediylbis(carbonothioylnitrilo)tetra |
Disulfiram, United States Pharmacopeia (USP) Reference Standard |
(diethylamino){(diethylamino)thioxomethyldisulfanyl}methane-1-thione |
1,1,1,1-disulfanediylbis(carbonothioylnitrilo)tetraethane |
Disulfiram, Pharmaceutical Secondary Standard; Certified Reference Material |
N,N-diethylcarbamodithioic acid diethylamino(sulfanylidene)methylthio ester |
Experimental Data
disulfiram
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Rattus norvegicus | 0.001000000000000 | % | 944.000000000000000 | 744.000000000000000 | -21.190000000000000 | Unclear | 5469789 | Inactive | |||||
| Rattus norvegicus | 0.002000000000000 | % | 944.000000000000000 | 896.000000000000000 | -5.080000000000000 | Unclear | 5469789 | Inactive | |||||
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -3.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
disulfiram
Statistics Data
disulfiram
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -3.000000000000000 | 1 | 1 | |
| Rattus norvegicus | -5.080000000000000 | 1 | 2 |
Statistics Data Visualization
disulfiram
