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Compound Summary

diazoxide

Compound Information

diazoxide

Compound Name:	diazoxide
Compound CID:	3019
Synonyms:	diazoxide 364-98-7 Proglycem Eudemine Hyperstat More...
Iupac Name:	7-chloro-3-methyl-4H-1lambda6,2,4-benzothiadiazine 1,1-dioxide
InChI:	InChI=1S/C8H7ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-4H,1H3,(H,10,11)
InChIKey:	GDLBFKVLRPITMI-UHFFFAOYSA-N
Canonical Smiles:	CC1=NS(=O)(=O)C2=C(N1)C=CC(=C2)Cl
Isomeric Smiles:	CC1=NS(=O)(=O)C2=C(N1)C=CC(=C2)Cl
Molecular Weight:	230.67
Molecular Formula:	C8H7ClN2O2S

Compound Structure

2D Structure:

3D Structure:

Computed Properties

diazoxide

Molecular Weight:	230.67
Molecular Formula:	C8H7ClN2O2S
Hydrogen Bond Donor Count:	1
Hydrogen Bond Acceptor Count:	3
Rotatable Bond Count:	0
Heavy Atom Count:	14
Complexity:	360

Synonyms

diazoxide

diazoxide	diazoxide
diazoxide	364-98-7
Proglycem	Eudemine
Hyperstat	Hypertonalum
Proglicem	Dizoxide
Mutabase	7-Chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
Diazossido	Sch 6783
Sch-6783	Diazoxido
Diazoxidum	SRG 95213
SRG-95213	C8H7ClN2O2S
2H-1,2,4-Benzothiadiazine, 7-chloro-3-methyl-, 1,1-dioxide	UNII-O5CB12L4FN
NSC 76130	NSC-64198
CHEBI:4495	MFCD00078578
O5CB12L4FN	3-methyl-7-chloro-1,2,4-benzothiadiazine 1,1-dioxide
MLS000028459	7-Cloro-3-metil-2H-1,2,4-benzotiodiazina-1,1-diossido
364-98-7 (free)	7-chloro-3-methyl-4H-1$l^{6},2,4-benzothiadiazine 1,1-dioxide
Diazossido Italian	NSC64198
NSC76130	NSC-76130
7-Chloro-3-methyl-2H-1,2,4-benzothiadiazine1,1-dioxide	Diazossido DCIT
NCGC00015380-09	CAS-364-98-7
SMR000058392	7-Chloro-3-methyl-2H-benzoe1,2,4thiadiazine 1,1-dioxide
DSSTox_CID_2914	Diazoxidum INN-Latin
DSSTox_RID_76786	Diazoxido INN-Spanish
DSSTox_GSID_22914	7-chloro-3-methyl-4h-1,2,4-benzothiadiazine 1,1-dioxide
Aroglycem	7-chloro-3-methyl-4H-benzoe1,2,4thiadiazine 1,1-dioxide
Hyperstat (TN)	SR-01000075314
EINECS 206-668-1	NSC 64198
7-Chloro-3-methyl-2H-1,4-benzothiadiazine 1,1-dioxide	Diazoxide (JAN/USP/INN)
Eudimine	2H-1,4-Benzothiadiazine, 7-chloro-3-methyl-, 1,1-dioxide
7-chloro-3-methyl-2H-1?^{6},2,4-benzothiadiazine 1,1-dioxide	Eudemine injection
7-Cloro-3-metil-2H-1,2,4-benzotiodiazina-1,1-diossido Italian	Proglycem (TN)
Prestwick_163	Diazoxide USAN:USP:INN:BAN:JAN
Tocris-0964	Opera_ID_608
Prestwick0_000087	Prestwick1_000087
Prestwick2_000087	Prestwick3_000087
Spectrum3_000735	Spectrum4_001248
Lopac-D-9035	CHEMBL181
D 9035	CBiol_001750
Lopac0_000404	SCHEMBL41254
BSPBio_000014	BSPBio_001307
BSPBio_002290	KBioGR_000027
KBioGR_001776	KBioSS_000027
MLS001076071	MLS001424164
SPECTRUM2300206	SPBio_001953
BPBio1_000016	GTPL2409
CHEMBL1518123	DTXSID7022914
BDBM86248	KBio2_000027
KBio2_002595	KBio2_005163
KBio3_000053	KBio3_000054
KBio3_001510	AOB5782
Bio1_000036	Bio1_000525
Bio1_001014	Bio2_000027
Bio2_000507	HMS1361B09
HMS1568A16	HMS1791B09
HMS1922L22	HMS1989B09
HMS2051P20	HMS2089L04
HMS2093N12	HMS2095A16
HMS2234B23	HMS3261A10
HMS3267I11	HMS3371L13
HMS3393P20	HMS3402B09
HMS3411L18	HMS3675L18
HMS3712A16	HMS3885H12
Pharmakon1600-02300206	2H-1,2, 4-Benzothiadiazine, 7-chloro-3-methyl-, 1,1-dioxide
7-Chloro-3-methyl-1lambda~4~,2,4-benzothiadiazin-1-ol 1-oxide	7-chloro-3-methyl-4H-1lambda6,2,4-benzothiadiazine 1,1-dioxide
BCP26107	HY-B1140
NSC_3019	ZINC3872277
Tox21_110132	Tox21_500404
BDBM50237612	KC-115
NSC759574	s4630
AKOS015896340	AKOS024458715
Tox21_110132_1	ACN-054388
CCG-101062	CCG-204497
CS-4745	DB01119
KS-1444	LP00404
MCULE-5031397425	NC00312
NSC-759574	SDCCGSBI-0050390.P002
IDI1_033777	Diazoxide 100 microg/mL in Acetonitrile
NCGC00015380-01	NCGC00015380-02
NCGC00015380-03	NCGC00015380-04
NCGC00015380-05	NCGC00015380-06
NCGC00015380-07	NCGC00015380-08
NCGC00015380-10	NCGC00015380-11
NCGC00015380-12	NCGC00015380-13
NCGC00015380-20	NCGC00022882-03
NCGC00024907-01	NCGC00024907-02
NCGC00024907-03	NCGC00024907-04
NCGC00024907-05	NCGC00024907-06
NCGC00024907-07	NCGC00024907-08
NCGC00261089-01	CAS_364-98-7
SY066792	DB-048966
B6526	D5402
EU-0100404	FT-0603087
Z3125	VU0239714-6
2270-EP2281815A1	2270-EP2295550A2
2270-EP2301933A1	2270-EP2308838A1
2270-EP2311827A1	C06949
D00294	F12855
32273-EP2281815A1	32273-EP2298415A1
32273-EP2301933A1	32273-EP2305640A2
32273-EP2311827A1	364D987
A823275	Q420009
SR-01000075314-1	SR-01000075314-3
SR-01000075314-4	SR-01000075314-6
BRD-K73109821-001-05-2	BRD-K73109821-001-10-2
7-chloro-3-methyl-1,2,4-benzothiadiazine,1,1-dioxide	Diazoxide, European Pharmacopoeia (EP) Reference Standard
4H-1,2,4-Benzothiadiazine, 7-chloro-3-methyl-, 1,1-dioxide	7-chloro-3-methyl-4H-1\|E?,2,4-benzothiadiazine-1,1-dione
7-chloro-3-methyl-4h-1\|E6,2,4-benzothiadiazine 1,1-dioxide	Diazoxide, United States Pharmacopeia (USP) Reference Standard
7-chloro-3-methyl-2H-1$l^{6},2,4-benzothiadiazine 1,1-dioxide	7-chloro-3-methyl-4H-1$l^{6},2,4-benzothiadiazine-1,1-dione

Experimental Data

diazoxide

Species	Dose	Unit	Control(Avg days)	Treatment(Avg days)	Avg/Med Lifespan Change(%)	Control(Max days)	Treatment(Max days)	Max Lifespan Change(%)	Significant	Strain	Gender	PubMed	Avg/Med Lifespan Change tab
Caenorhabditis elegans	33.000000000000000	umol/L			11.000000000000000				NS	N2		24134630	Inactive

Experimental Data Visualization

diazoxide

Statistics Data

diazoxide

Species	Avg/Med Lifespan Change(%)	Max Lifespan Change(%)	Count Reference	Count Data point
Caenorhabditis elegans	11.000000000000000		1	1

Statistics Data Visualization

diazoxide

Compound Name:

diazoxide

Compound CID:

3019

Synonyms:

diazoxide 364-98-7 Proglycem Eudemine Hyperstat More...

Iupac Name:

7-chloro-3-methyl-4H-1lambda6,2,4-benzothiadiazine 1,1-dioxide

InChI:

InChI=1S/C8H7ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-4H,1H3,(H,10,11)

InChIKey:

GDLBFKVLRPITMI-UHFFFAOYSA-N

Canonical Smiles:

CC1=NS(=O)(=O)C2=C(N1)C=CC(=C2)Cl

Isomeric Smiles:

CC1=NS(=O)(=O)C2=C(N1)C=CC(=C2)Cl

Molecular Weight:

230.67

Molecular Formula:

C8H7ClN2O2S

Molecular Weight:

230.67

Molecular Formula:

C8H7ClN2O2S

Hydrogen Bond Donor Count:

1

Hydrogen Bond Acceptor Count:

3

Rotatable Bond Count:

0

Heavy Atom Count:

14

Complexity:

360

diazoxide

364-98-7

Proglycem

Eudemine

Hyperstat

Hypertonalum

Proglicem

Dizoxide

Mutabase

7-Chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide

Diazossido

Sch 6783

Sch-6783

Diazoxido

Diazoxidum

SRG 95213

SRG-95213

C8H7ClN2O2S

2H-1,2,4-Benzothiadiazine, 7-chloro-3-methyl-, 1,1-dioxide

UNII-O5CB12L4FN

NSC 76130

NSC-64198

CHEBI:4495

MFCD00078578

O5CB12L4FN

3-methyl-7-chloro-1,2,4-benzothiadiazine 1,1-dioxide

MLS000028459

7-Cloro-3-metil-2H-1,2,4-benzotiodiazina-1,1-diossido

364-98-7 (free)

7-chloro-3-methyl-4H-1$l^{6},2,4-benzothiadiazine 1,1-dioxide

Diazossido Italian

NSC64198

NSC76130

NSC-76130

7-Chloro-3-methyl-2H-1,2,4-benzothiadiazine1,1-dioxide

Diazossido DCIT

NCGC00015380-09

CAS-364-98-7

SMR000058392

7-Chloro-3-methyl-2H-benzoe1,2,4thiadiazine 1,1-dioxide

DSSTox_CID_2914

Diazoxidum INN-Latin

DSSTox_RID_76786

Diazoxido INN-Spanish

DSSTox_GSID_22914

7-chloro-3-methyl-4h-1,2,4-benzothiadiazine 1,1-dioxide

diazoxide

364-98-7

Proglycem

Eudemine

Hyperstat

More...