Compound Summary
dexverapamil
Compound Information
dexverapamil
Compound Name: | dexverapamil |
Compound CID: | 65808 |
Synonyms: | Dexverapamil 38321-02-7 Dexverapamilum (R)-verapamil (+)-verapamil More... |
Iupac Name: | (2R)-2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile |
InChI: | InChI=1S/C27H38N2O4/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6/h9-12,17-18,20H,8,13-16H2,1-7H3/t27-/m1/s1 |
InChIKey: | SGTNSNPWRIOYBX-HHHXNRCGSA-N |
Canonical Smiles: | CC(C)C(CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC |
Isomeric Smiles: | CC(C)[C@@](CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC |
Molecular Weight: | 454.6 |
Molecular Formula: | C27H38N2O4 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
dexverapamil
Molecular Weight: | 454.6 |
Molecular Formula: | C27H38N2O4 |
Hydrogen Bond Donor Count: | 0 |
Hydrogen Bond Acceptor Count: | 6 |
Rotatable Bond Count: | 13 |
Heavy Atom Count: | 33 |
Complexity: | 606 |
Synonyms
dexverapamil
| dexverapamil | dexverapamil |
|---|---|
Dexverapamil |
38321-02-7 |
Dexverapamilum |
(R)-verapamil |
(+)-verapamil |
Dexverapamilo |
Dexverapamil INN |
(+)-(R)-verapamil |
(R)-(+)-verapamil |
d-verapamil |
Verapamil, (r)- |
R(+)-VERAPAMIL |
QR5PYD126V |
CHEBI:77734 |
(+)-3-(3,4-dimethoxyphenyl)-6-(5,6-dimethoxyphenethyl)methylaminohexane-3-carbonitrile |
(2R)-2-(3,4-dimethoxyphenyl)-5-2-(3,4-dimethoxyphenyl)ethyl-methylamino-2-propan-2-ylpentanenitrile |
(+)-(R)-5-((3,4-Dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile |
(+)-3-(3,4-Dimethoxyphenyl)-6-((5,6-dimethoxyphenethyl)methylamino)hexane-3-carbonitrile |
(R)-5-((3,4-dimethoxyphenethyl)(methyl)amino)-2-(3,4-dimethoxyphenyl)-2-isopropylpentanenitrile |
UNII-QR5PYD126V |
Dexverapamilum INN-Latin |
Dexverapamilo INN-Spanish |
Verapramil |
verapamil-r |
EINECS 253-878-4 |
Verapamil (r)-form |
CHEMBL197 |
VERAPAMIL, (+)- |
SCHEMBL33297 |
DTXSID501009404 |
VERAPAMIL (R)-FORM MI |
VERAPAMIL, (+)-(R)- |
VERAPAMIL, (R)-(+)- |
2-(3,4-dimethoxy-phenyl)-5-{2-(3,4-dimethoxy-phenyl)-ethyl-methyl-amino}-2-isopropyl-pentanenitrile |
ZINC3812888 |
BDBM50338982 |
DB14063 |
NCI60_010786 |
Q27147324 |
4-3,4-dimethoxyphenethyl(methyl)amino-1-(3,4-dimethoxyphenyl)-1-isopropylbutyl cyanide |
(+)-(2R)-2-(3,4-dimethoxyphenyl)-5-{2-(3,4-dimethoxyphenyl)ethyl(methyl)amino}-2-(propan-2-yl)pentanenitrile |
(+)-2-(3,4-dimethoxyphenyl)-5-{2-(3,4-dimethoxyphenyl)ethyl(methyl)amino}-2-(propan-2-yl)pentanenitrile |
(.ALPHA.R)-.ALPHA.-(3-((2-(3,4-DIMETHOXYPHENYL)ETHYL)METHYLAMINO)PROPYL)-3,4-DIMETHOXY-.ALPHA.-(1-METHYLETHYL)BENZENEACETONITRILE |
(2R)-(+)-2-(3,4-dimethoxyphenyl)-5-{2-(3,4-dimethoxyphenyl)ethyl(methyl)amino}-2-(propan-2-yl)pentanenitrile |
(2R)-2-(3,4-dimethoxyphenyl)-5-{2-(3,4-dimethoxyphenyl)ethyl(methyl)amino}-2-(propan-2-yl)pentanenitrile |
(S)-2-(3,4-Dimethoxy-phenyl)-5-{2-(3,4-dimethoxy-phenyl)-ethyl-methyl-amino}-2-isopropyl-pentanenitrile |
(S)-2-(3,4-Dimethoxy-phenyl)-5-{2-(3,4-dimethoxy-phenyl)-ethyl-methyl-amino}-2-isopropyl-pentanenitrile; hydrochloride |
(Verapamil) 2-(3,4-Dimethoxy-phenyl)-5-{2-(3,4-dimethoxy-phenyl)-ethyl-methyl-amino}-2-isopropyl-pentanenitrile |
5-{2-(3,4-Dimethoxy-phenyl)-ethyl-methyl-amino}-2-isopropyl-2-(3,4,5-trimethoxy-phenyl)-pentanenitrile |
5-{2-(3,4-Dimethoxy-phenyl)-ethyl-methyl-amino}-2-isopropyl-2-(4-methoxy-phenyl)-pentanenitrile |
BENZENEACETONITRILE, .ALPHA.-(3-((2-(3,4-DIMETHOXYPHENYL)ETHYL)METHYLAMINO)PROPYL)-3,4-DIMETHOXY-.ALPHA.-(1-METHYLETHYL)-, (R)- |
I6H |
Verapamil;2-(3,4-Dimethoxy-phenyl)-5-{2-(3,4-dimethoxy-phenyl)-ethyl-methyl-amino}-2-isopropyl-pentanenitrile |
Experimental Data
dexverapamil
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 50.000000000000000 | umol/L | 2.180000000000000 | NS | N2 | 30970250 | Inactive |
Experimental Data Visualization
dexverapamil
Statistics Data
dexverapamil
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 2.180000000000000 | 1 | 1 |
Statistics Data Visualization
dexverapamil
