Compound Summary

curcumin
  Compound Information
 curcumin

Compound Name:

curcumin

Compound CID:

969516

Synonyms:

curcumin

458-37-7

Diferuloylmethane

Natural yellow 3

Turmeric yellow

More...

Iupac Name:

(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione

InChI:

InChI=1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+

InChIKey:

VFLDPWHFBUODDF-FCXRPNKRSA-N

Canonical Smiles:

COC1=C(C=CC(=C1)C=CC(=O)CC(=O)C=CC2=CC(=C(C=C2)O)OC)O

Isomeric Smiles:

COC1=C(C=CC(=C1)/C=C/C(=O)CC(=O)/C=C/C2=CC(=C(C=C2)O)OC)O

Molecular Weight:

368.4

Molecular Formula:

C21H20O6

  Compound Structure
 2D Structure:
 3D Structure:
  Computed Properties
 curcumin

Molecular Weight:

368.4

Molecular Formula:

C21H20O6

Hydrogen Bond Donor Count:

2

Hydrogen Bond Acceptor Count:

6

Rotatable Bond Count:

8

Heavy Atom Count:

27

Complexity:

507

  Synonyms
 curcumin

curcumin curcumin

curcumin

458-37-7

Diferuloylmethane

Natural yellow 3

Turmeric yellow

Turmeric

Indian saffron

Curcuma

Kacha haldi

Gelbwurz

Curcumin I

Souchet

Haidr

Halad

Haldar

Halud

(1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione

Merita earth

Terra Merita

Yellow Ginger

Yellow Root

Safran dInde

Yo-Kin

Curcuma oil

Golden seal

Orange Root

C.I. Natural Yellow 3

Curcumine

Hydrastis

Indian turmeric

Yellow puccoon

Diferaloylmethane

Turmeric oleoresin

Kurkumin Czech

Tumeric yellow

CI Natural Yellow 3

Zlut prirodni 3 Czech

Cucurmin

C.I. 75300

Tumeric oleoresin

8024-37-1

Curcumin (synthetic)

E 100

Curcurmin

1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione

NSC32982

UNII-IT942ZTH98

MFCD00008365

NSC 32982

Turmeric (>98% curcurmin)

CHEBI:3962

MLS000069631

Turmeric oleoresin (79%-85% curcumin)

CI 75300

Turmeric extract

Oils, curcuma

1,9-Bis(4-hydroxy-3-methoxyphenyl)-2,7-nonadiene-4,6-dione

CHEMBL140

(1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione

1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxy-3-methoxyphenyl)-, (E,E)-

SMR000058237

1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxy-3-methoxyphenyl)-, (1E,6E)-

IT942ZTH98

1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione

Turmeric oil

Oil of turmeric

(E,E)-1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione

NSC-32982

NSC687842

Curcuma longa oils

94875-80-6

NCGC00017159-05

Kurkumin

DSSTox_CID_1421

(1E,6E)-1,7-bis(4-hydroxy-3-methoxy-phenyl)hepta-1,6-diene-3,5-dione

(1E,6E)-1,7-bis4-hydroxy-3-(methyloxy)phenylhepta-1,6-diene-3,5-dione

Zlut prirodni 3

Turmeric root oil

DSSTox_RID_78861

DSSTox_GSID_31077

Turmeric, oleoresin

Curcuma oil (Curcuma longa)

Turmeric oil (Curcuma longa L.)

Curcuma longa l. root oil

CAS-458-37-7

FEMA No. 3085

FEMA No. 3086

CCRIS 3257

CCRIS 5804

HSDB 4334

1,5-Di(vanillyliden)acetylaceton

NCI-C61325

SR-01000000149

1,5-Divanillyliden-2,4-pentandion

EINECS 207-280-5

NSC 687842

BRN 2306965

diferuloylmethan

E 100 (Dye)

Curcumin solution

Haldar, Souchet

Turmeric; Curcuma

Curcumin,(S)

trans,trans-Curcumin

Opera_ID_1627

SCHEMBL8440

SCHEMBL8441

Curcumin, analytical standard

4-08-00-03697 (Beilstein Handbook Reference)

MLS001148449

BIDD:ER0479

CU-01000001305-2

turmeric root oil CO2 extract

cid_969516

GTPL7000

turmeric root oil hydrodistilled

DTXSID8031077

SCHEMBL13521974

BDBM29532

cid_5281767

cMAP_000052

HMS2233K04

HMS3649K06

ZINC899824

2,7-Nonadiene-4,6-dione, 1,9-bis(4-hydroxy-3-methoxyphenyl)-

91884-86-5

AMY33436

BCP04695

HY-N0005

Tox21_110803

Tox21_111505

Tox21_201116

BBL027711

BDBM50067040

BDBM50140172

CC0179

CCG-36020

CCG-36107

SBB006495

STL371943

AKOS001305497

BCP9000557

CS-1490

curcuma longa l. root oil CO2 extract

DB11672

curcuma longa l. root oil hydrodistilled

NCGC00017159-04

NCGC00017159-06

NCGC00017159-07

NCGC00017159-09

NCGC00017159-10

NCGC00017159-11

NCGC00017159-12

NCGC00023332-03

NCGC00023332-04

NCGC00023332-05

NCGC00258668-01

AC-24238

AS-72202

BP-25396

M212

ST055629

BCP0726000035

DB-002681

WLN: 1OR BQ E1U1V1V1U1R DQ CO1

C-230

N1839

1,3-Di(3-methoxy-4-hydroxystyryl)propanedial

1790-EP2305629A1

1790-EP2308861A1

F21478

J10108

K00009

Curcumin, Curcuma longa L. - CAS 458-37-7

Curcumin, from Curcuma longa (Turmeric), powder

458C377

A826902

Curcumin, primary pharmaceutical reference standard

Q312266

1,5-dione, 1,7-bis(4-hydroxy-3-methoxyphenyl)-

SR-01000000149-2

SR-01000000149-5

BRD-K07572174-001-02-2

BRD-K07572174-001-19-6

BRD-K07572174-001-22-0

Curcumin, >=94% (curcuminoid content), >=80% (Curcumin)

1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadien-3,5-dione

1,7-bis(4-hydroxy-3-methoxyphenyl)1,6-heptadiene-3,5-dione

Curcumin, (total curcuminoid content), from Turmeric rhizome

Curcumin, matrix substance for MALDI-MS, >=99.5% (HPLC)

Curcumin, United States Pharmacopeia (USP) Reference Standard

1,7-Bis-(4-hydroxy-3-methoxy-phenyl)-hepta-1,6-diene-3,5-dione

1,7-bis-(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione

((E,E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione)

(1E,6E)-1,7-bis(3-methoxy-4-oxidanyl-phenyl)hepta-1,6-diene-3,5-dione

(1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione #

(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione.

(1E,6E)-1,7-Bis-(4-hydroxy-3-methoxy-phenyl)-hepta-1,6-diene-3,5-dione

(1Z,6E)-1,7-Bis-(4-hydroxy-3-methoxy-phenyl)-hepta-1,6-diene-3,5-dione

1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, (E,E)-

5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,4,6-heptatrien-3-one

5-Hydroxy-1,7-bis-(4-hydroxy-3-methoxy-phenyl)-hepta-1,4,6-trien-3-one

Curcumin; 1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione

(1E,4Z,6E)-5-Hydroxy-1,7-bis-(4-hydroxy-3-methoxy-phenyl)-hepta-1,4,6-trien-3-one

(E,E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione (Synthetic)

Curcumin solution, ~0.1 % (w/v) (in ethanol with 2M HCl (99:1 v/v)), for TLC derivatization
  Experimental Data
 curcumin

Species Dose Unit Control(Avg days) Treatment(Avg days) Avg/Med Lifespan Change(%) Control(Max days) Treatment(Max days) Max Lifespan Change(%) Significant Strain Gender PubMed Avg/Med Lifespan Change tab
Caenorhabditis elegans 100.000000000000000 mM 15.440000000000000 17.390000000000000 12.620000000000000 18.000000000000000 23.000000000000000 27.770000000000000 S N2 27810360 Active
Drosophila melanogaster 200.000000000000000 mM 0.000000000000000 NS Ra 23063786 Inactive
Apis mellifera 1.000000000000000 ug/mL 0.000000000000000 NS 34580381 Inactive
Drosophila melanogaster 100.000000000000000 mM 0.000000000000000 S Ra 23063786 Active
Drosophila melanogaster 10.000000000000000 mM 0.000000000000000 NS Ra 23063786 Inactive
Apis mellifera 100.000000000000000 ug/mL 0.000000000000000 S 34580381 Active
Apis mellifera 10.000000000000000 ug/mL 0.000000000000000 NS 34580381 Inactive
Caenorhabditis elegans 10.000000000000000 umol/L Unclear N2 33683565
Caenorhabditis elegans 20.000000000000000 umol/L Unclear N2 33683565
Caenorhabditis elegans 200.000000000000000 umol/L Unclear N2 33683565
Caenorhabditis elegans 100.000000000000000 umol/L Unclear N2 33683565
Drosophila melanogaster 0.500000000000000 mg 30.000000000000000 33.000000000000000 10.000000000000000 58.000000000000000 55.000000000000000 -5.100000000000000 NS Oregon-R MALES 22653297 Inactive
Drosophila melanogaster 100.000000000000000 umol/L 19.000000000000000 S FEMALES 20645870 Active
Drosophila melanogaster 0.200000000000000 mg/g 35.600000000000000 38.000000000000000 0.070000000000000 57.000000000000000 62.000000000000000 0.090000000000000 S Canton-S FEMALES 30488487 Active
Drosophila melanogaster 1.000000000000000 mg 23.000000000000000 24.000000000000000 4.600000000000000 54.000000000000000 61.000000000000000 13.000000000000000 S Oregon-R FEMALES 22653297 Active
Caenorhabditis elegans 20.000000000000000 umol/L 15.500000000000000 16.600000000000000 0.070000000000000 27.000000000000000 25.000000000000000 -0.070000000000000 NS N2 31534071 Inactive
Caenorhabditis elegans 100.000000000000000 umol/L 17.080000000000000 16.240000000000000 -4.893000000000000 NS N2 33008901 Inactive
Drosophila melanogaster 0.200000000000000 mg/g 36.500000000000000 37.600000000000000 0.030000000000000 61.000000000000000 64.000000000000000 0.050000000000000 NS Canton-S MALES 30488487 Inactive
Drosophila melanogaster 100.000000000000000 mM 46.800000000000000 38.000000000000000 S FEMALES 26136617 Active
Drosophila melanogaster 1.000000000000000 mg 30.000000000000000 38.000000000000000 26.700000000000000 58.000000000000000 55.000000000000000 -5.100000000000000 S Oregon-R MALES 22653297 Active
Caenorhabditis elegans 100.000000000000000 umol/L 15.000000000000000 16.000000000000000 6.250000000000000 NS N2 29263362 Inactive
Drosophila melanogaster 0.500000000000000 mg 23.000000000000000 26.000000000000000 13.000000000000000 54.000000000000000 53.000000000000000 -1.900000000000000 S Oregon-R FEMALES 22653297 Active
Drosophila melanogaster 10.000000000000000 mM 27.140000000000000 32.340000000000000 0.190000000000000 57.000000000000000 65.000000000000000 0.140000000000000 S Canton-S 25173182 Active
Drosophila melanogaster 0.500000000000000 g/L 51.000000000000000 49.000000000000000 -0.040000000000000 NS MALES 33951964 Inactive
Drosophila melanogaster 100.000000000000000 mM -23.400000000000000 S FEMALES 26136617 Inactive
Drosophila melanogaster 5.000000000000000 mM 27.140000000000000 27.680000000000000 0.020000000000000 57.000000000000000 53.000000000000000 -0.070000000000000 S Canton-S 25173182 Active
Caenorhabditis elegans 20.000000000000000 umol/L 20.100000000000000 25.400000000000000 0.260000000000000 30.000000000000000 33.000000000000000 0.100000000000000 S N2 31534071 Active
Caenorhabditis elegans 200.000000000000000 umol/L 8.400000000000000 8.800000000000000 0.050000000000000 NS N2 21855561 Inactive
Drosophila melanogaster 100.000000000000000 mM -17.000000000000000 -3.000000000000000 S FEMALES 26136617 Inactive
Drosophila melanogaster 10.000000000000000 mM 33.770000000000000 45.370000000000000 0.340000000000000 76.000000000000000 95.000000000000000 0.250000000000000 S Canton-S 25173182 Active
Drosophila melanogaster 2.000000000000000 g/L 51.000000000000000 58.000000000000000 0.140000000000000 S MALES 33951964 Active
Mus musculus 2000.000000000000000 kg/mg 786.000000000000000 808.000000000000000 0.030000000000000 NS UM-HET3 MALES 22451473 Inactive
Caenorhabditis elegans 20.000000000000000 umol/L 8.400000000000000 11.700000000000000 0.390000000000000 S N2 21855561 Active
Caenorhabditis elegans 10.000000000000000 umol/L 16.740000000000000 15.550000000000000 -7.106000000000000 NS N2 33008901 Inactive
Drosophila melanogaster 5.000000000000000 mM 33.770000000000000 35.670000000000000 0.060000000000000 76.000000000000000 88.000000000000000 0.160000000000000 S Canton-S 25173182 Active
Drosophila melanogaster 25.000000000000000 mM 27.140000000000000 28.210000000000000 0.040000000000000 57.000000000000000 61.000000000000000 0.070000000000000 S Canton-S 25173182 Active
Drosophila melanogaster 250.000000000000000 umol/L 16.000000000000000 S MALES 20645870 Active
Drosophila melanogaster 50.000000000000000 mM 33.770000000000000 34.860000000000000 0.030000000000000 76.000000000000000 89.000000000000000 0.170000000000000 S Canton-S 25173182 Active
Caenorhabditis elegans 100.000000000000000 umol/L 22.540000000000000 15.070000000000000 Unclear N2 33683565
Drosophila melanogaster 50.000000000000000 mM 27.140000000000000 26.810000000000000 -0.010000000000000 57.000000000000000 59.000000000000000 0.040000000000000 S Canton-S 25173182 Inactive
Drosophila melanogaster 100.000000000000000 mM 25.500000000000000 0.000000000000000 S FEMALES 26136617 Active
Drosophila melanogaster 200.000000000000000 umol/L 44.800000000000000 44.810000000000000 0.014290000000000 NS MALES 33008901 Inactive
Drosophila melanogaster 0.500000000000000 g/L 61.000000000000000 63.000000000000000 0.030000000000000 NS FEMALES 33951964 Inactive
Drosophila melanogaster 25.000000000000000 mM 33.770000000000000 36.990000000000000 0.100000000000000 76.000000000000000 95.000000000000000 0.250000000000000 S Canton-S 25173182 Active
Drosophila melanogaster 1.000000000000000 mg 63.900000000000000 76.900000000000000 0.200000000000000 S Wild 1-A 23675008 Active
Drosophila melanogaster 20.000000000000000 umol/L 45.440000000000000 46.530000000000000 2.407000000000000 NS FEMALES 33008901 Inactive
Caenorhabditis elegans 0.050000000000000 ug/mL 11.000000000000000 11.500000000000000 0.050000000000000 19.000000000000000 20.000000000000000 0.050000000000000 NS N2 29550283 Inactive
Mus musculus 2000.000000000000000 kg/mg 866.000000000000000 905.000000000000000 0.050000000000000 NS UM-HET3 FEMALES 22451473 Inactive
Caenorhabditis elegans 100.000000000000000 umol/L 17.300000000000000 21.200000000000000 0.230000000000000 27.200000000000000 31.300000000000000 0.150000000000000 NS N2 25959406 Inactive
Drosophila melanogaster 1.000000000000000 g/L 51.000000000000000 52.000000000000000 0.020000000000000 NS MALES 33951964 Inactive
Drosophila melanogaster 2.000000000000000 g/L 61.000000000000000 68.000000000000000 0.110000000000000 S FEMALES 33951964 Active
Drosophila melanogaster 1.000000000000000 g/L 61.000000000000000 66.000000000000000 0.080000000000000 S FEMALES 33951964 Active
  Experimental Data Visualization
 curcumin

  Statistics Data
 curcumin

Species Avg/Med Lifespan Change(%) Max Lifespan Change(%) Count Reference Count Data point
Apis mellifera 0.000000000000000 1 3
Caenorhabditis elegans 22.540000000000000 27.770000000000000 8 15
Drosophila melanogaster 46.800000000000000 38.000000000000000 9 32
Mus musculus 0.050000000000000 1 2
  Statistics Data Visualization
 curcumin

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