Compound Summary

clozapine
  Compound Information
 clozapine

Compound Name:

clozapine

Compound CID:

135398737

Synonyms:

clozapine

5786-21-0

Leponex

Clozapin

CLOZARIL

More...

Iupac Name:

3-chloro-6-(4-methylpiperazin-1-yl)-11H-benzo[b][1,4]benzodiazepine

InChI:

InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3

InChIKey:

QZUDBNBUXVUHMW-UHFFFAOYSA-N

Canonical Smiles:

CN1CCN(CC1)C2=NC3=C(C=CC(=C3)Cl)NC4=CC=CC=C42

Isomeric Smiles:

CN1CCN(CC1)C2=NC3=C(C=CC(=C3)Cl)NC4=CC=CC=C42

Molecular Weight:

326.8

Molecular Formula:

C18H19ClN4

  Compound Structure
 2D Structure:
 3D Structure:
  Computed Properties
 clozapine

Molecular Weight:

326.8

Molecular Formula:

C18H19ClN4

Hydrogen Bond Donor Count:

1

Hydrogen Bond Acceptor Count:

3

Rotatable Bond Count:

1

Heavy Atom Count:

23

Complexity:

446

  Synonyms
 clozapine

clozapine clozapine

clozapine

5786-21-0

Leponex

Clozapin

CLOZARIL

Fazaclo

Clorazil

Iprox

Clozapina

Clozapinum

HF 1854

HF-1854

8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzob,e1,4diazepine

W-801

8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzob,e1,4diazepine

UNII-J60AR2IKIC

5H-Dibenzob,e1,4diazepine, 8-chloro-11-(4-methyl-1-piperazinyl)-

C18H19ClN4

3-chloro-6-(4-methylpiperazin-1-yl)-5H-benzob1,4benzodiazepine

8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine

LX 100-129

CHEMBL42

MFCD00153785

J60AR2IKIC

Clozapine resolution mixture

5H-Dibenzo(b,e)(1,4)diazepine, 8-chloro-11-(4-methyl-1-piperazinyl)-

MLS000028472

CHEBI:3766

Asaleptin

Lepotex

Fazaclo ODT

NCGC00015254-12

SMR000058365

CAS-5786-21-0

3-chloro-6-(4-methylpiperazin-1-yl)-11H-benzob1,4benzodiazepine

8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzob,e1,4diazepine

DSSTox_CID_2855

Clozapinum INN-Latin

DSSTox_RID_76759

Clozapina INN-Spanish

DSSTox_GSID_22855

Azaleptine

Versacloz

Clozaril (TN)

6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo9.4.0.0^{3,8}pentadeca-1,3(8),4,6,10,12,14-heptaene

CCRIS 9171

HSDB 6478

SR-01000000096

EINECS 227-313-7

BRN 0764984

Clozapine (JAN/USP/INN)

Clozapine, solid

Clozapine solution

LEX-123

Clozapine USAN:USP:INN:BAN

Prestwick_693

Clozapine - Bio-X

Clozapine (Clozaril)

KS-1166

Spectrum_000139

Tocris-0444

CPD000058365

Opera_ID_482

Prestwick0_000350

Prestwick1_000350

Spectrum2_000919

Spectrum3_001828

Spectrum4_000898

Lopac-C-6305

8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzob,e1,4-diazepine

GTPL38

C 6305

SCHEMBL8397

REGID_for_CID_2818

SCHEMBL33323

KBioGR_000310

KBioGR_001336

KBioSS_000310

KBioSS_000599

MLS001077282

DivK1c_000343

SPECTRUM1500685

SPBio_000798

SPBio_002340

DTXSID5022855

BDBM22869

CHEBI:92657

HMS501B05

KBio1_000343

KBio2_000310

KBio2_000599

KBio2_002878

KBio2_003167

KBio2_005446

KBio2_005735

KBio3_000619

KBio3_000620

KBio3_002979

AOB5635

NINDS_000343

Bio1_000436

Bio1_000925

Bio1_001414

Bio2_000310

Bio2_000790

HMS1361P12

HMS1569E21

HMS1791P12

HMS1921C16

HMS1989P12

HMS2089L13

HMS2092I16

HMS2096E21

HMS2235E19

HMS3259J17

HMS3260H14

HMS3266A10

HMS3371H05

HMS3402P12

HMS3414F09

HMS3657E15

HMS3678F09

HMS3713E21

HMS3742K03

Pharmakon1600-01500685

BCP25196

ZINC3872123

Tox21_110113

Tox21_500276

BDBM50001884

CC0176

CCG-39881

NSC757429

s2459

ZINC19796155

Clozapine 1.0 mg/ml in Acetonitrile

8-Chloro-11-(4-methyl)-1-piperazinyl)-5H-dibenzob,e1,4diazepine

AKOS005064444

AKOS026749900

Tox21_110113_1

CS-0644

DB00363

LP00276

MCULE-3665900006

NC00667

NSC 757429

NSC-757429

SDCCGSBI-0050264.P005

NCGC00015254-01

NCGC00015254-02

NCGC00015254-03

NCGC00015254-04

NCGC00015254-05

NCGC00015254-06

NCGC00015254-07

NCGC00015254-08

NCGC00015254-09

NCGC00015254-10

NCGC00015254-11

NCGC00015254-13

NCGC00015254-14

NCGC00015254-15

NCGC00015254-16

NCGC00015254-17

NCGC00015254-18

NCGC00015254-20

NCGC00015254-31

NCGC00022902-02

NCGC00022902-04

NCGC00022902-05

NCGC00022902-06

NCGC00022902-07

NCGC00022902-08

NCGC00022902-09

NCGC00022902-10

NCGC00022902-11

NCGC00022902-12

NCGC00022902-13

NCGC00188978-01

NCGC00260961-01

BC164328

H482

HY-14539

SBI-0050264.P004

AB0013069

DB-053121

D-107

EU-0100276

SW220247-1

EN300-52510

C06924

D00283

H10436

AB00052158-13

AB00052158-14

AB00052158_15

AB00052158_16

786C210

Clozapine, drug standard, 1.0 mg/mL in methanol

L000195

L013417

Q221361

SR-01000000096-2

SR-01000000096-4

SR-01000000096-5

SR-01000000096-8

W-105432

BRD-K37289225-001-09-1

BRD-K37289225-001-23-2

Clozapine, British Pharmacopoeia (BP) Reference Standard

Z1245633277

Clozapine, European Pharmacopoeia (EP) Reference Standard

Clozapine, United States Pharmacopeia (USP) Reference Standard

8-Chloro-11-(4-methylpiperazino)-5H-dibenzob,e1,4diazepine

(E)-8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzob,e1,4diazepine

3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzob,e1,4diazepine

8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzob,e1,4diazepine

3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo3.2.1oct-3-yl ester

8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzob,e1,4diazepine (Clozapine)

8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzob,e1,4diazepine( Clozepine )

8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzob,e1,4diazepine(Ciozapine)

8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzob,e1,4diazepine(Clopazine)

Clozapine for peak identification, European Pharmacopoeia (EP) Reference Standard

Clozapine Resolution Mixture, United States Pharmacopeia (USP) Reference Standard

Clozapine solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material

CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZOB,E1,4DIAZEPINE

1333667-72-3

6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo9.4.0.03,8pentadeca-1(11),3,5,7,9,12,14-heptaene
  Experimental Data
 clozapine

Species Dose Unit Control(Avg days) Treatment(Avg days) Avg/Med Lifespan Change(%) Control(Max days) Treatment(Max days) Max Lifespan Change(%) Significant Strain Gender PubMed Avg/Med Lifespan Change tab
Caenorhabditis elegans 33.000000000000000 umol/L 19.000000000000000 NS N2 24134630 Inactive
  Experimental Data Visualization
 clozapine

  Statistics Data
 clozapine

Species Avg/Med Lifespan Change(%) Max Lifespan Change(%) Count Reference Count Data point
Caenorhabditis elegans 19.000000000000000 1 1
  Statistics Data Visualization
 clozapine

Home | Browse | Search | Predict | Data | Contact | Help

Copyright © KUST | 滇ICP备16009434号-1 | Dai SX Lab