ACDB Search

Compound Summary

clofibrate

Compound Information

clofibrate

Compound Name:	clofibrate
Compound CID:	2796
Synonyms:	clofibrate 637-07-0 Ethyl 2-(4-chlorophenoxy)-2-methylpropanoate Ethyl clofibrate Atromid More...
Iupac Name:	ethyl 2-(4-chlorophenoxy)-2-methylpropanoate
InChI:	InChI=1S/C12H15ClO3/c1-4-15-11(14)12(2,3)16-10-7-5-9(13)6-8-10/h5-8H,4H2,1-3H3
InChIKey:	KNHUKKLJHYUCFP-UHFFFAOYSA-N
Canonical Smiles:	CCOC(=O)C(C)(C)OC1=CC=C(C=C1)Cl
Isomeric Smiles:	CCOC(=O)C(C)(C)OC1=CC=C(C=C1)Cl
Molecular Weight:	242.7
Molecular Formula:	C12H15ClO3

Compound Structure

2D Structure:

3D Structure:

Computed Properties

clofibrate

Molecular Weight:	242.7
Molecular Formula:	C12H15ClO3
Hydrogen Bond Donor Count:	0
Hydrogen Bond Acceptor Count:	3
Rotatable Bond Count:	5
Heavy Atom Count:	16
Complexity:	232

Synonyms

clofibrate

clofibrate	clofibrate
clofibrate	637-07-0
Ethyl 2-(4-chlorophenoxy)-2-methylpropanoate	Ethyl clofibrate
Atromid	Clofibratum
Clofibrato	Liprin
Atromid-S	Miscleron
EPIB	Angiokapsul
Antilipid	Antilipide
Arterioflexin	Arterosol
Ateriosan	Athebrate
Atheromide	Atheropront
Chlorphenisate	Clofibate
Lipofacton	Ticlobran
Amotril	Anparton
Ateculon	Atrolen
Atromida	Lipavil
Lipavlon	Lipomid
Liprinal	Xyduril
Apolan	Amotril S
Ethyl chlorophenoxyisobutyrate	Athranid-wirkstoff
Atromidin	Bioscleran
Cartagyl	Citiflus
Claripex	Clofibram
Clofibrat	Clofinit
Clofipront	Fibralem
Gerastop	Hyclorate
Klofibrat	Klofiran
Levatrom	Lipidsenker
Liponorm	Liporeduct
Lobetrin	Normalip
Persantinat	Regardin
Serotinex	Skleromexe
Atrovis	Azionyl
Bresit	Clobrat
Clofar	Delipid
Deliva	Lipamid
Liporil	Liposid
Normat	Regelan
Sklero	Dura clofibrat
Sklero-Tablinen	neo-Atomid
Neo-Atromid	Atromid S
Claripex CPIB	Clobren-SF
ELPI	Cinnarizin
Cloberat	Misclerone
Normolipol	Robigram
Skerolip	Artevil
Negalip	Normet
Recolip	Scrobin
Yoclo	Sklero-tabuls
Regelan N	2-(4-Chlorophenoxy)-2-methylpropanoic acid ethyl ester
Lipide 500	Chlorfenisate
Oxan 600	Ethyl 2-(p-chlorophenoxy)isobutyrate
Artes	Propanoic acid, 2-(4-chlorophenoxy)-2-methyl-, ethyl ester
2-(p-Chlorophenoxy)-2-methylpropionic acid ethyl ester	Ethyl para-chlorophenoxyisobutyrate
Ethyl 2-(4-chlorophenoxy)-2-methylpropionate	NSC-79389
ICI 28257	Ethyl p-chlorophenoxyisobutyrate
AY 61123	AY-61123
alpha-p-Chlorophenoxyisobutyryl ethyl ester	Ethyl 2-(4-chlorophenoxy)isobutyrate
alpha-(p-Chlorophenoxy)isobutyric acid, ethyl ester	UNII-HPN91K7FU3
Ethyl 2-(p-chlorophenoxy)-2-methylpropionate	19 more names available
ICI-28257	CHEMBL565
HPN91K7FU3	Acetic acid, (p-chlorophenoxy)dimethyl-, ethyl ester
CHEBI:3750	Propanoic acid, 2-(p-chlorophenoxy)-2-methyl-, ethyl ester
Propionic acid, 2-(4-chlorophenoxy)-2-methyl-, ethyl ester	Propionic acid, 2-(p-chlorophenoxy)-2-methyl-, ethyl ester
.alpha.-p-Chlorophenoxyisobutyryl ethyl ester	2-(4-Chlorophenoxy)isobutyric Acid Ethyl Ester
NSC79389	MFCD00000615
.alpha.-(p-Chlorophenoxy)isobutyric acid, ethyl ester	NCGC00015257-08
Sklerepmexe	Serofinex
Sklerolip	Skleromex
Clofibrato Spanish	Ethyl .alpha.-(4-chlorophenoxy)isobutyrate
Ethyl .alpha.-(p-chlorophenoxy)isobutyrate	DSSTox_CID_336
Sklero-tablinene	Clobren-5F
DSSTox_RID_75521	Vincamin compositum
Clofibratum INN-Latin	DSSTox_GSID_20336
Clofibrato INN-Spanish	ethyl 2-(4-chlorophenyl)oxy-2-methylpropanoate
Ethyl .alpha.-(p-chlorophenoxy)-.alpha.-methylpropionate	Ethyl .alpha.-(4-chlorophenoxy)-.alpha.-methylpropionate
Abitrate	CAS-637-07-0
SMR000058279	CCRIS 177
clofibrate (CLOF)	Ethyl-alpha-p-chlorophenoxy-isobutyrate
Ethyl alpha-(4-chlorophenoxy)isobutyrate	Ethyl alpha-(p-chlorophenoxy)isobutyrate
HSDB 3038	SR-01000075544
EINECS 211-277-4	ATROMID-S (TN)
NSC 79389	BRN 1913459
BML2-F02	Clofibrate liquid
Clobren SF	Clofibrate, liquid
Ethyl alpha-(4-chlorophenoxy)-alpha-methylpropionate	Ethyl alpha-(p-Chlorophenoxy)-alpha-methylpropionate
Clofibrate USAN:USP:INN:BAN:JAN	Isobutyric acid, alpha-(p-chlorophenoxy)-, ethyl ester
Ethyl 2-(para-chlorophenoxy)-2-methylpropionate (IUPAC)	Spectrum_001735
p-Chlorophenoxyisobutyric acid ethyl ester	Spectrum2_001209
Spectrum4_000223	Spectrum5_001133
Lopac-C-6643	UPCMLD-DP019
C 6643	ethyl 2-(4-chlorophenoxy)-2-methyl-propanoate
SCHEMBL2356	NCIOpen2_004739
BIDD:PXR0178	CBiol_001860
Lopac0_000306	BSPBio_001577
KBioGR_000297	KBioGR_000885
KBioSS_000297	KBioSS_002215
MLS001336011	MLS001336012
MLS002153494	BIDD:GT0172
DivK1c_000822	DivK1c_000926
SPBio_000998	Clofibrate (JP17/USP/INN)
GTPL2667	2-(4-Chlorophenoxy)-2-methylpropionic acid ethyl ester
DTXSID3020336	UPCMLD-DP019:001
BCBcMAP01_000104	HMS502J04
HMS502O08	KBio1_000822
KBio1_000926	KBio2_000297
KBio2_002215	KBio2_002865
KBio2_004783	KBio2_005433
KBio2_007351	KBio3_000593
KBio3_000594	WLN: GR DOX1&1&VO2
ZINC56648	Clofibrate, >=98.0% (GC)
NINDS_000822	NINDS_000926
Bio1_000146	Bio1_000635
Bio1_001124	Bio2_000297
Bio2_000777	HMS1361O19
HMS1791O19	HMS1989O19
HMS2089P03	HMS2093G07
HMS2233C17	HMS3260N14
HMS3373C06	HMS3402O19
HMS3715J03	Pharmakon1600-01503429
EBD52899	HY-B0287
Tox21_110116	Tox21_202414
Tox21_300277	Tox21_500306
BDBM50085047	CCG-40281
NSC758474	SBB099633
AKOS015889383	Tox21_110116_1
DB00636	LP00306
MCULE-9236719628	NSC-758474
SDCCGSBI-0050294.P004	IDI1_000822
IDI1_000926	IDI1_034047
Clofibrate, analytical reference material	NCGC00015257-01
NCGC00015257-02	NCGC00015257-03
NCGC00015257-04	NCGC00015257-05
NCGC00015257-06	NCGC00015257-07
NCGC00015257-09	NCGC00015257-10
NCGC00015257-11	NCGC00015257-12
NCGC00015257-14	NCGC00015257-22
NCGC00093755-01	NCGC00093755-03
NCGC00093755-04	NCGC00093755-05
NCGC00093755-06	NCGC00093755-07
NCGC00093755-08	NCGC00254073-01
NCGC00259963-01	NCGC00260991-01
AC-33179	AS-14127
K009	NCI60_041748
Ethyl .alpha.-p-(chlorophenoxy)isobutyrate	SBI-0050294.P003
AB0013973	DB-054528
EU-0100306	FT-0625865
FT-0665112	S1820
ST50319977	2-(p-Chlorophenoxy)isobutyric acid ethyl ester
C06916	D00279
F20382	AB00052358-07
AB00052358-08	AB00052358_09
AB00052358_10	Ethyl 2-(4-chlorophenoxy)-2-methylpropanoate #
A834483	ethyl 2-(4-chloranylphenoxy)-2-methyl-propanoate
Acetic acid, (p-chlorophenoxy)dimethyl-, ethyl este	Ethyl 2-(4-chlorophenoxy)-2-methylpropionate, 99%
Q2701912	SR-01000075544-1
SR-01000075544-4	SR-01000075544-5
SR-01000075544-8	Z53835984
2-(p-chlorophenoxy)-2-methylPropanoic acid ethyl ester	2-(p-chlorophenoxy)-2-methylpropionic acid ethyl ester;
2-(4-Chloro-phenoxy)-2-methyl-propionic acid ethyl ester	Clofibrate, European Pharmacopoeia (EP) Reference Standard
Isobutyric acid, .alpha.-(p-chlorophenoxy)-, ethyl ester	Clofibrate, United States Pharmacopeia (USP) Reference Standard

Experimental Data

clofibrate

Species	Dose	Unit	Control(Avg days)	Treatment(Avg days)	Avg/Med Lifespan Change(%)	Control(Max days)	Treatment(Max days)	Max Lifespan Change(%)	Significant	Strain	PubMed	Avg/Med Lifespan Change tab
Caenorhabditis elegans	1.000000000000000	umol/L	21.600000000000000	22.600000000000000	0.050000000000000	28.100000000000000	27.200000000000000	-0.030000000000000	NS	N2	23603800	Inactive
Caenorhabditis elegans	10.000000000000000	umol/L	21.600000000000000	25.100000000000000	0.160000000000000	28.100000000000000	33.800000000000000	0.200000000000000	S	N2	23603800	Active
Caenorhabditis elegans	0.100000000000000	umol/L	21.600000000000000	22.000000000000000	0.020000000000000	28.100000000000000	25.900000000000000	-0.080000000000000	NS	N2	23603800	Inactive
Caenorhabditis elegans	33.000000000000000	umol/L			-5.000000000000000				NS	N2	24134630	Inactive
Caenorhabditis elegans	10.000000000000000	umol/L	21.600000000000000	23.000000000000000	0.060000000000000	28.100000000000000	34.200000000000000	0.220000000000000	S	N2	23603800	Active

Experimental Data Visualization

clofibrate

Statistics Data

clofibrate

Species	Avg/Med Lifespan Change(%)	Max Lifespan Change(%)	Count Reference	Count Data point
Caenorhabditis elegans	0.160000000000000	0.220000000000000	2	5

Statistics Data Visualization

clofibrate

Compound Name:

clofibrate

Compound CID:

2796

Synonyms:

clofibrate 637-07-0 Ethyl 2-(4-chlorophenoxy)-2-methylpropanoate Ethyl clofibrate Atromid More...

Iupac Name:

ethyl 2-(4-chlorophenoxy)-2-methylpropanoate

InChI:

InChI=1S/C12H15ClO3/c1-4-15-11(14)12(2,3)16-10-7-5-9(13)6-8-10/h5-8H,4H2,1-3H3

InChIKey:

KNHUKKLJHYUCFP-UHFFFAOYSA-N

Canonical Smiles:

CCOC(=O)C(C)(C)OC1=CC=C(C=C1)Cl

Isomeric Smiles:

CCOC(=O)C(C)(C)OC1=CC=C(C=C1)Cl

Molecular Weight:

242.7

Molecular Formula:

C12H15ClO3

Molecular Weight:

242.7

Molecular Formula:

C12H15ClO3

Hydrogen Bond Donor Count:

0

Hydrogen Bond Acceptor Count:

3

Rotatable Bond Count:

5

Heavy Atom Count:

16

Complexity:

232

clofibrate

637-07-0

Ethyl 2-(4-chlorophenoxy)-2-methylpropanoate

Ethyl clofibrate

Atromid

Clofibratum

Clofibrato

Liprin

Atromid-S

Miscleron

EPIB

Angiokapsul

Antilipid

Antilipide

Arterioflexin

Arterosol

Ateriosan

Athebrate

Atheromide

Atheropront

Chlorphenisate

Clofibate

Lipofacton

Ticlobran

Amotril

Anparton

Ateculon

Atrolen

Atromida

Lipavil

Lipavlon

Lipomid

Liprinal

Xyduril

Apolan

Amotril S

Ethyl chlorophenoxyisobutyrate

Athranid-wirkstoff

Atromidin

Bioscleran

Cartagyl

Citiflus

Claripex

Clofibram

Clofibrat

Clofinit

clofibrate

637-07-0

Ethyl 2-(4-chlorophenoxy)-2-methylpropanoate

Ethyl clofibrate

Atromid

More...