Compound Summary
cinoxacin
Compound Information
cinoxacin
Compound Name: | cinoxacin |
Compound CID: | 2762 |
Synonyms: | cinoxacin 28657-80-9 Cinobac Compound 64716 Cinobactin More... |
Iupac Name: | 1-ethyl-4-oxo-[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid |
InChI: | InChI=1S/C12H10N2O5/c1-2-14-7-4-9-8(18-5-19-9)3-6(7)11(15)10(13-14)12(16)17/h3-4H,2,5H2,1H3,(H,16,17) |
InChIKey: | VDUWPHTZYNWKRN-UHFFFAOYSA-N |
Canonical Smiles: | CCN1C2=CC3=C(C=C2C(=O)C(=N1)C(=O)O)OCO3 |
Isomeric Smiles: | CCN1C2=CC3=C(C=C2C(=O)C(=N1)C(=O)O)OCO3 |
Molecular Weight: | 262.22 |
Molecular Formula: | C12H10N2O5 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
cinoxacin
Molecular Weight: | 262.22 |
Molecular Formula: | C12H10N2O5 |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 7 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 19 |
Complexity: | 449 |
Synonyms
cinoxacin
| cinoxacin | cinoxacin |
|---|---|
cinoxacin |
28657-80-9 |
Cinobac |
Compound 64716 |
Cinobactin |
Cinoxacine |
Cinoxacino |
Cinoxacinum |
Uronorm |
Cinx |
UNII-LMK22VUH23 |
1-Ethyl-6,7-methylenedioxy-4(1H)-oxocinnoline-3-carboxylic acid |
NSC 304467 |
MLS000069630 |
1-ethyl-4-oxo-1,3dioxolo4,5-gcinnoline-3-carboxylic acid |
LMK22VUH23 |
1-Ethyl-1,4-dihydro-4-oxo(1,3)dioxolo(4,5-g)cinnoline-3-carboxylic acid |
1-Ethyl-1,4-dihydro-4-oxo1,3dioxolo4,5-gcinnoline-3-carboxylic acid |
SMR000058232 |
1,3Dioxolo4,5-gcinnoline-3-carboxylic acid, 1-ethyl-1,4-dihydro-4-oxo- |
CHEBI:3716 |
1-Ethyl-4-oxo-1,4-dihydro-1,3dioxolo4,5-gcinnoline-3-carboxylic acid |
1-Ethyl-4-oxo-1,4-dihydro1,3dioxolo4,5-gcinnoline-3-carboxylic acid |
NSC304467 |
NSC-304467 |
NCGC00015277-02 |
CAS-28657-80-9 |
DSSTox_CID_2822 |
(1,3)Dioxolo(4,5-g)cinnoline-3-carboxylic acid, 1,4-dihydro-1-ethyl-4-oxo- |
(1,3)Dioxolo(4,5-g)cinnoline-3-carboxylic acid, 1-ethyl-1,4-dihydro-4-oxo- |
DSSTox_RID_76745 |
Cinoxacine INN-French |
Cinoxacinum INN-Latin |
DSSTox_GSID_22822 |
Cinoxacino INN-Spanish |
Lilly 64716 |
1-ethyl-4-oxo-1H,4H,7H-1,3dioxolo4,5-gcinnoline-3-carboxylic acid |
1-ethyl-4-oxohydro-7H-1,3-dioxoleno4,5-gcinnoline-3-carboxylic acid |
Cinobac (TN) |
SR-01000000129 |
EINECS 249-133-8 |
BRN 1084304 |
Noxigram |
CCRIS 8206 |
TNP00246 |
Prestwick_239 |
Cinoxacin USAN:USP:INN:BAN:JAN |
Spectrum_000152 |
Opera_ID_1392 |
Prestwick0_000780 |
Prestwick1_000780 |
Prestwick2_000780 |
Prestwick3_000780 |
Spectrum2_000570 |
Spectrum3_000352 |
Spectrum4_000289 |
Spectrum5_000749 |
Lopac-C-8645 |
C 8645 |
cid_2762 |
CHEMBL1208 |
Lopac0_000309 |
Oprea1_131085 |
SCHEMBL43770 |
BSPBio_000860 |
BSPBio_002043 |
KBioGR_000818 |
KBioSS_000632 |
MLS001148076 |
DivK1c_000318 |
SPECTRUM1500190 |
SPBio_000360 |
SPBio_002799 |
Cinoxacin (JP17/USP/INN) |
BPBio1_000946 |
DTXSID8022822 |
BDBM39350 |
HMS500P20 |
KBio1_000318 |
KBio2_000632 |
KBio2_003200 |
KBio2_005768 |
KBio3_001263 |
ZINC32350 |
NINDS_000318 |
HMS1570K22 |
HMS1920O11 |
HMS2091E18 |
HMS2097K22 |
HMS2235K07 |
HMS3260N20 |
HMS3370B19 |
HMS3714K22 |
Pharmakon1600-01500190 |
HY-B1085 |
Tox21_110121 |
Tox21_500309 |
2323AH |
CCG-39160 |
MFCD00056776 |
NSC756695 |
SBB003082 |
AKOS022507372 |
Tox21_110121_1 |
CS-4652 |
DB00827 |
LP00309 |
MCULE-3390574434 |
NSC-756695 |
SDCCGSBI-0050297.P005 |
IDI1_000318 |
NCGC00015277-01 |
NCGC00015277-03 |
NCGC00015277-04 |
NCGC00015277-05 |
NCGC00015277-06 |
NCGC00015277-07 |
NCGC00015277-08 |
NCGC00015277-09 |
NCGC00015277-10 |
NCGC00015277-11 |
NCGC00015277-12 |
NCGC00015277-13 |
NCGC00015277-14 |
NCGC00015277-17 |
NCGC00015277-21 |
NCGC00023754-03 |
NCGC00023754-04 |
NCGC00023754-05 |
NCGC00023754-06 |
NCGC00023754-07 |
NCGC00260994-01 |
AS-73151 |
ST044511 |
SBI-0050297.P004 |
DB-047427 |
EU-0100309 |
FT-0602947 |
SW196546-3 |
C08052 |
D00872 |
AB00051948_17 |
AB00051948_18 |
A819523 |
J-017182 |
Q1639588 |
SR-01000000129-2 |
SR-01000000129-4 |
SR-01000000129-7 |
BRD-K14704277-001-05-1 |
BRD-K14704277-001-15-0 |
1-Ethyl-1,3dioxolo4,5-gcinnoline-3-carboxylic acid |
Cinoxacin, United States Pharmacopeia (USP) Reference Standard |
1,5-gcinnoline-3-carboxylic acid, 1-ethyl-1,4-dihydro-4-oxo- |
1-Ethyl-1,4-dihydro-4-oxo(1,3)dioxolo(4,5-g)cinnoline-3-carboxylicacid |
1-ethyl-4-oxidanylidene-1,3dioxolo4,5-gcinnoline-3-carboxylic acid |
5-Ethyl-8-oxo-5,8-dihydro-1,3-dioxa-5,6-diaza-cyclopentabnaphthalene-7-carboxylic acid |
Experimental Data
cinoxacin
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 100.000000000000000 | umol/L | 16.480000000000000 | 15.660000000000000 | -4.949000000000000 | NS | N2 | 33008901 | Inactive | ||||
| Drosophila melanogaster | 200.000000000000000 | umol/L | 42.220000000000000 | 41.310000000000000 | -2.160000000000000 | NS | MALES | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 10.000000000000000 | umol/L | 16.080000000000000 | 14.160000000000000 | -11.990000000000000 | NS | N2 | 33008901 | Inactive | ||||
| Drosophila melanogaster | 20.000000000000000 | umol/L | 47.990000000000000 | 45.770000000000000 | -4.620000000000000 | NS | FEMALES | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 33.000000000000000 | umol/L | 1.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
cinoxacin
Statistics Data
cinoxacin
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 1.000000000000000 | 2 | 3 | |
| Drosophila melanogaster | -2.160000000000000 | 1 | 2 |
Statistics Data Visualization
cinoxacin
