Compound Summary
cilostamide
Compound Information
cilostamide
Compound Name: | cilostamide |
Compound CID: | 2753 |
Synonyms: | cilostamide 68550-75-4 ciloalamide N-Cyclohexyl-N-methyl-4-(1,2-dihydro-2-oxo-6-quinolyloxy)butyramide OPC 3689 More... |
Iupac Name: | N-cyclohexyl-N-methyl-4-[(2-oxo-1H-quinolin-6-yl)oxy]butanamide |
InChI: | InChI=1S/C20H26N2O3/c1-22(16-6-3-2-4-7-16)20(24)8-5-13-25-17-10-11-18-15(14-17)9-12-19(23)21-18/h9-12,14,16H,2-8,13H2,1H3,(H,21,23) |
InChIKey: | UIAYVIIHMORPSJ-UHFFFAOYSA-N |
Canonical Smiles: | CN(C1CCCCC1)C(=O)CCCOC2=CC3=C(C=C2)NC(=O)C=C3 |
Isomeric Smiles: | CN(C1CCCCC1)C(=O)CCCOC2=CC3=C(C=C2)NC(=O)C=C3 |
Molecular Weight: | 342.4 |
Molecular Formula: | C20H26N2O3 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
cilostamide
Molecular Weight: | 342.4 |
Molecular Formula: | C20H26N2O3 |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 6 |
Heavy Atom Count: | 25 |
Complexity: | 499 |
Synonyms
cilostamide
| cilostamide | cilostamide |
|---|---|
cilostamide |
68550-75-4 |
ciloalamide |
N-Cyclohexyl-N-methyl-4-(1,2-dihydro-2-oxo-6-quinolyloxy)butyramide |
OPC 3689 |
UNII-45S5605Q18 |
CHEMBL34431 |
N-cyclohexyl-N-methyl-4-(2-oxo-1H-quinolin-6-yl)oxybutanamide |
MFCD00673958 |
NCGC00015269-03 |
45S5605Q18 |
N-Cyclohexyl-4-((1,2-dihydro-2-oxo-6-quinolyl)oxy)-N-methylbutyramide |
N-Cyclohexyl-N-methyl-4-((2-oxo-1,2-dihydroquinolin-6-yl)oxy)butanamide |
N-cyclohexyl-N-methyl-4-(2-oxo-1,2-dihydroquinolin-6-yl)oxybutanamide |
DSSTox_CID_25140 |
DSSTox_RID_80698 |
DSSTox_GSID_45140 |
Cilostamide INN |
Cilostamida |
Cilostamidum |
Cilostamidum INN-Latin |
Cilostamida INN-Spanish |
CAS-68550-75-4 |
SR-01000075781 |
OPC 3869 |
Tocris-0915 |
Lopac-C-7971 |
ACMC-20f49n |
Butanamide, N-cyclohexyl-4-((1,2-dihydro-2-oxo-6-quinolinyl)oxy)-N-methyl- |
Lopac0_000288 |
SCHEMBL49742 |
GTPL5167 |
DTXSID3045140 |
BDBM15297 |
CHEBI:92503 |
HMS2090J06 |
HMS3260J18 |
HMS3267A21 |
HMS3411F22 |
HMS3675F22 |
HMS3742E05 |
6-3-(N-Cyclohexyl-N-methylcarbamoyl)propoxyquinolin-21H-one |
BCP08355 |
OCP 3689 |
ZINC3872076 |
Tox21_110119 |
Tox21_500288 |
BDBM50027177 |
HSCI1_000142 |
AKOS024458692 |
Cilostamide - CAS 68550-75-4 |
Cilostamide phosphodiesterase inhibitor |
Tox21_110119_1 |
CCG-204383 |
Cilostamide, phosphodiesterase inhibitor |
LP00288 |
SB72501 |
SDCCGSBI-0050276.P002 |
NCGC00015269-01 |
NCGC00015269-02 |
NCGC00015269-04 |
NCGC00015269-05 |
NCGC00015269-06 |
NCGC00015269-11 |
NCGC00024869-01 |
NCGC00024869-02 |
NCGC00024869-03 |
NCGC00260973-01 |
AS-72168 |
HY-101312 |
B6500 |
CS-0021135 |
EU-0100288 |
S5806 |
A13596 |
C 7971 |
AB01275528-01 |
A930263 |
SR-01000075781-1 |
SR-01000075781-3 |
BRD-K28578425-001-01-3 |
BRD-K28578425-001-02-1 |
BRD-K28578425-001-03-9 |
BRD-K28578425-001-04-7 |
BRD-K28578425-001-06-2 |
Q15634085 |
6-3-(N-cyclohexyl-N-methylaminocarbonyl)propoxycarbostyril |
6-3-(N-methyl-N-cyclohexylaminocarbonyl)propoxy-carbostyril |
6-3-(N-methyl-N-cyclohexylaminocarbonyl)propoxycarbostyril |
N-Cyclohexyl-4-((2-hydroxyquinolin-6-yl)oxy)-N-methylbutanamide |
N-Cyclohexyl-N-methyl-4-(2-oxo-1,2-dihydro-quinolin-6-yloxy)-butyramide |
BUTANAMIDE,N-CYCLOHEXYL-4-(1,2-DIHYDRO-2-OXO-6-QUINOLINYL)OXY-N-METHYL- |
Experimental Data
cilostamide
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | 10.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
cilostamide
Statistics Data
cilostamide
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 10.000000000000000 | 1 | 1 |
Statistics Data Visualization
cilostamide
