Compound Summary
carmustine
Compound Information
carmustine
Compound Name: | carmustine |
Compound CID: | 2578 |
Synonyms: | carmustine 154-93-8 1,3-Bis(2-chloroethyl)-1-nitrosourea BCNU Carmustin More... |
Iupac Name: | 1,3-bis(2-chloroethyl)-1-nitrosourea |
InChI: | InChI=1S/C5H9Cl2N3O2/c6-1-3-8-5(11)10(9-12)4-2-7/h1-4H2,(H,8,11) |
InChIKey: | DLGOEMSEDOSKAD-UHFFFAOYSA-N |
Canonical Smiles: | C(CCl)NC(=O)N(CCCl)N=O |
Isomeric Smiles: | C(CCl)NC(=O)N(CCCl)N=O |
Molecular Weight: | 214.05 |
Molecular Formula: | C5H9Cl2N3O2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
carmustine
Molecular Weight: | 214.05 |
Molecular Formula: | C5H9Cl2N3O2 |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 12 |
Complexity: | 156 |
Synonyms
carmustine
| carmustine | carmustine |
|---|---|
carmustine |
154-93-8 |
1,3-Bis(2-chloroethyl)-1-nitrosourea |
BCNU |
Carmustin |
Gliadel |
Nitrumon |
Carmubris |
BiCNU |
Bi CNU |
Carmustinum |
1,3-Bis(2-chloroethyl)nitrosourea |
Bischloroethyl nitrosourea |
Bischlorethylnitrosurea |
N,N-BIS(2-CHLOROETHYL)-N-NITROSOUREA |
Bischlorethylnitrosourea |
Carmustina |
Urea, N,N-bis(2-chloroethyl)-N-nitroso- |
Bis(2-chloroethyl)nitrosourea |
NSC-409962 |
FDA 0345 |
SRI 1720 |
BiCNU (TN) |
DTI 015 |
NCI-C04773 |
SK 27702 |
Carmustine (98%) |
Bis(chloroethyl)nitrosourea |
NSC 409962 |
UNII-U68WG3173Y |
bis-chloroethylnitrosourea |
NSC409962 |
CHEMBL513 |
1,3-bis(2-chloroethyl)-1-nitroso-urea |
CHEBI:3423 |
Urea, 1,3-bis(2-chloroethyl)-1-nitroso- |
Becenum |
Becenun |
U68WG3173Y |
MFCD00057706 |
1,3-bis(2-chloroethyl)-3-nitrosourea |
NCGC00015204-05 |
1,3-Bis(.beta.-chloroethyl)-1-nitrosourea |
Gliadel Wafer |
Bischloroethylnitrosourea |
DSSTox_CID_2743 |
DSSTox_RID_76712 |
Carmustinum INN-Latin |
DSSTox_GSID_22743 |
Carmustina INN-Spanish |
Bis(2-chloroethyl)1-nitrosourea |
Bis-N,N-(chloroethyl)nitrosourea |
C5H9Cl2N3O2 |
CAS-154-93-8 |
CCRIS 810 |
1,3-Bis(beta-chloroethyl)-1-nitrosourea |
BCNU Chloroethyl nitrosoureas |
SR-01000075736 |
EINECS 205-838-2 |
BRN 2049744 |
Carustine |
AI3-52216 |
HSDB 7761 |
BiCNU; Nitrumon |
Carmustine USAN:USP:INN:BAN |
Carmustine- Bio-X |
Prestwick_997 |
Gliadel (TN) |
Bischloroethyl nitrosourea Chloroethyl nitrosoureas |
Gliadel (MGI Pharm) |
Spectrum_000265 |
Carmustine, >=98% |
Spectrum4_000888 |
Spectrum5_000920 |
Lopac-C-0400 |
WLN: ONN2GVM2G |
C 0400 |
SCHEMBL4503 |
Lopac0_000188 |
Carmustine (JAN/USP/INN) |
KBioGR_001296 |
KBioSS_000745 |
MLS001333962 |
DivK1c_000835 |
AMY382 |
GTPL6800 |
DTXSID8022743 |
HMS502J17 |
KBio1_000835 |
KBio2_000745 |
KBio2_003313 |
KBio2_005881 |
AOB6824 |
DTI-015 |
NINDS_000835 |
HMS2092J22 |
HMS2230I05 |
HMS3260F17 |
HMS3369D17 |
Pharmakon1600-01503110 |
BCP27690 |
FDA-0345 |
SRI-1720 |
ZINC3830387 |
Tox21_110097 |
Tox21_500188 |
BDBM50015950 |
CCG-39925 |
NSC758392 |
STK624770 |
AKOS005558013 |
Tox21_110097_1 |
BCP9000490 |
DB00262 |
LP00188 |
MCULE-3131772074 |
NSC-758392 |
SDCCGSBI-0050176.P004 |
IDI1_000835 |
Urea,3-bis(2-chloroethyl)-1-nitroso- |
NCGC00015204-01 |
NCGC00015204-02 |
NCGC00015204-03 |
NCGC00015204-04 |
NCGC00015204-06 |
NCGC00015204-07 |
NCGC00015204-08 |
NCGC00015204-09 |
NCGC00015204-18 |
NCGC00093665-01 |
NCGC00093665-02 |
NCGC00093665-03 |
NCGC00093665-04 |
NCGC00260873-01 |
Urea,N-bis(2-chloroethyl)-N-nitroso- |
AC-24196 |
AS-12106 |
BC164289 |
HY-13585 |
N,N-Bis(2-chloroethyl)-N-nitrosourea |
NCI60_003931 |
SK-27702 |
SMR000058426 |
SBI-0050176.P003 |
AB0011283 |
EU-0100188 |
FT-0602937 |
S3669 |
BCNU; 1,3-Bis(2-chloroethyl)-1-nitrosourea |
C06873 |
D00254 |
13167-EP2270014A1 |
13167-EP2272827A1 |
13167-EP2272832A1 |
13167-EP2275420A1 |
13167-EP2277876A1 |
13167-EP2292614A1 |
13167-EP2295055A2 |
13167-EP2295416A2 |
13167-EP2295426A1 |
13167-EP2295427A1 |
13167-EP2298748A2 |
13167-EP2298764A1 |
13167-EP2298765A1 |
13167-EP2298768A1 |
13167-EP2298778A1 |
13167-EP2305642A2 |
13167-EP2308861A1 |
13167-EP2311453A1 |
13167-EP2311808A1 |
13167-EP2311825A1 |
13167-EP2311829A1 |
13167-EP2311842A2 |
13167-EP2314590A1 |
13167-EP2316832A1 |
13167-EP2316833A1 |
13167-EP2316834A1 |
13167-EP2374454A1 |
15164-EP2272827A1 |
15164-EP2316832A1 |
15164-EP2316833A1 |
AB00052431-07 |
AB00052431_08 |
154C938 |
A809590 |
Q415869 |
SR-01000075736-1 |
SR-01000075736-3 |
W-108025 |
Z1563145982 |
Carmustine, United States Pharmacopeia (USP) Reference Standard |
1-(2-Chloroethyl)-1-((2-chloroethyl)aminocarbonyl)-2-oxohydrazine # |
Experimental Data
carmustine
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -11.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
carmustine
Statistics Data
carmustine
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -11.000000000000000 | 1 | 1 |
Statistics Data Visualization
carmustine
