Compound Summary
carbidopa
Compound Information
carbidopa
Compound Name: | carbidopa |
Compound CID: | 34359 |
Synonyms: | carbidopa 28860-95-9 Lodosyn (S)-(-)-carbidopa Carbidopa anhydrous More... |
Iupac Name: | (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid |
InChI: | InChI=1S/C10H14N2O4/c1-10(12-11,9(15)16)5-6-2-3-7(13)8(14)4-6/h2-4,12-14H,5,11H2,1H3,(H,15,16)/t10-/m0/s1 |
InChIKey: | TZFNLOMSOLWIDK-JTQLQIEISA-N |
Canonical Smiles: | CC(CC1=CC(=C(C=C1)O)O)(C(=O)O)NN |
Isomeric Smiles: | C[C@](CC1=CC(=C(C=C1)O)O)(C(=O)O)NN |
Molecular Weight: | 226.23 |
Molecular Formula: | C10H14N2O4 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
carbidopa
Molecular Weight: | 226.23 |
Molecular Formula: | C10H14N2O4 |
Hydrogen Bond Donor Count: | 5 |
Hydrogen Bond Acceptor Count: | 6 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 16 |
Complexity: | 261 |
Synonyms
carbidopa
| carbidopa | carbidopa |
|---|---|
carbidopa |
28860-95-9 |
Lodosyn |
(S)-(-)-carbidopa |
Carbidopa anhydrous |
(S)-carbidopa |
S-(-)-Carbidopa |
alpha-Methyldopahydrazine |
L-alpha-Methyldopahydrazine |
N-Aminomethyldopa |
Carbidopum |
Carbidopum INN-Latin |
Carbidopa (anhydrous) |
MK 486 |
S(-)-CARBIDOPA |
(2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid |
L-3-(3,4-Dihydroxyphenyl)-2-methyl-2-hydrazinopropionic acid |
UNII-KR87B45RGH |
38821-49-7 |
(2S)-3-(3,4-dihydroxyphenyl)-2-hydrazino-2-methylpropanoic acid |
(-)-L-alpha-Hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamic acid |
MK-486 |
(S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid |
KR87B45RGH |
CHEBI:39585 |
28860-95-9 (anhydrous) |
(alphaS)-alpha-hydrazino-3,4-dihydroxy-alpha-methylbenzenepropanoic acid |
MFCD00069231 |
NCGC00024596-05 |
Hadrazino-alpha-methyldopa |
C-DOPA |
3,3,3-trideuterio-2-dideuterio-(3,4-dihydroxyphenyl)methyl-2-hydrazinylpropanoic acid |
Carbidopa INN |
SMR000058235 |
CCRIS 5093 |
SR-01000597655 |
EINECS 249-271-9 |
alpha-Hydrazino-alpha-methyl-beta-(3,4-dihydroxyphenyl)propionic acid |
L-alpha-Methyl-alpha-hydrazino-beta-(3,4-dihydroxyphenylpropionic acid |
L-alpha-Methyl-beta-(3,4-dihydroxyphenyl)-alpha-hydrazinopropionic acid |
ND0611 |
Tocris-0455 |
C-126 |
DSSTox_CID_2735 |
DSSTox_RID_76707 |
DSSTox_GSID_22735 |
Lopac0_000382 |
SCHEMBL35084 |
MLS000069628 |
MLS002207014 |
S-(-)-Carbidopa monohydrate |
GTPL5159 |
CHEMBL1201236 |
DTXSID4022735 |
AOB5343 |
HMS2089B12 |
HMS3266A20 |
HMS3411M13 |
HMS3655G20 |
HMS3675M13 |
HMS3713L10 |
HMS3884M14 |
HY-B0311 |
Tox21_110910 |
(2S)-3-(3,4-dihydroxyphenyl)-2-hydrazino-2-methyl-propanoic acid |
BDBM50418773 |
NSC751137 |
S-(-)-alpha-Hydrazino-3,4-dihydroxy-2-methylbenzenepropanoic acid |
s1891 |
SBB000659 |
ZINC19168887 |
AKOS015969657 |
Benzenepropanoic acid, alpha-hydrazino-3,4-dihydroxy-alpha-methyl-, (S)- |
HYDROCINNAMIC ACID, alpha-HYDRAZINO-3,4-DIHYDROXY-alpha-METHYL-, L- |
AC-1676 |
CCG-204476 |
DB00190 |
NSC-751137 |
SDCCGMLS-0072919.P025 |
(+)-2-(3,4-Dihydroxybenzyl)-2-hydrazinopropionic acid monohydrate |
MLS-0072919 |
SMP1_000057 |
NCGC00024596-01 |
NCGC00024596-03 |
NCGC00024596-06 |
NCGC00024596-07 |
NCGC00024596-08 |
AS-16862 |
BC164279 |
ST055523 |
MLS-0072919.P013 |
CAS-28860-95-9 |
EU-0100382 |
SW199080-2 |
60C959 |
AB00441332-05 |
AB00441332-06 |
AB00441332_07 |
AB00441332_08 |
SR-01000597655-1 |
SR-01000597655-3 |
SR-01000597655-5 |
SR-01000597655-9 |
BRD-K78712176-001-07-5 |
Benzenepropanoic acid, a-hydrazino-3,4-dihydroxy-a-methyl- |
UNII-555UP07D5N component TZFNLOMSOLWIDK-JTQLQIEISA-N |
(S)-?-Hydrazino-?-methyl-?-(3,4-dihydroxyphenyl)propionic acid |
(S)-3-(3,4-Dihydroxyphenyl)-2-hydrazino-2-methylpropanoic acid |
(S)-3-(3,4-Dihydroxyphenyl)-2-hydrazino-2-methylpropionic Acid |
(2S)-3-(3,4-DIHYDROXYPHENYL)-2-HYDRAZINYL-2-METHYL-PROPANOIC ACID |
(2S)-3-(3,4-dihydroxyphenyl)-2-hydrazino-2-methylpropionic acid monohydrate |
KINSON; 3-(3,4-DIHYDROXY-PHENYL)-2-HYDRAZINO-2-METHYL-PROPIONIC ACID |
1426847-87-1 |
Experimental Data
carbidopa
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drosophila melanogaster | 200.000000000000000 | umol/L | 45.820000000000000 | 45.750000000000000 | -0.145900000000000 | NS | MALES | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 100.000000000000000 | umol/L | 17.140000000000000 | 16.710000000000000 | -2.485000000000000 | NS | N2 | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 10.000000000000000 | umol/L | 17.950000000000000 | 16.510000000000000 | -8.065000000000000 | NS | N2 | 33008901 | Inactive | ||||
| Drosophila melanogaster | 20.000000000000000 | umol/L | 49.360000000000000 | 48.660000000000000 | -1.407000000000000 | NS | FEMALES | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -2.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
carbidopa
Statistics Data
carbidopa
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -2.000000000000000 | 2 | 3 | |
| Drosophila melanogaster | -0.145900000000000 | 1 | 2 |
Statistics Data Visualization
carbidopa
