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Compound Summary

budesonide

Compound Information

budesonide

Compound Name:	budesonide
Compound CID:	5281004
Synonyms:	budesonide Pulmicort Rhinocort Entocort 51333-22-3 More...
Iupac Name:	(1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-6-propyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one
InChI:	InChI=1S/C25H34O6/c1-4-5-21-30-20-11-17-16-7-6-14-10-15(27)8-9-23(14,2)22(16)18(28)12-24(17,3)25(20,31-21)19(29)13-26/h8-10,16-18,20-22,26,28H,4-7,11-13H2,1-3H3/t16-,17-,18-,20+,21?,22+,23-,24-,25+/m0/s1
InChIKey:	VOVIALXJUBGFJZ-KWVAZRHASA-N
Canonical Smiles:	CCCC1OC2CC3C4CCC5=CC(=O)C=CC5(C4C(CC3(C2(O1)C(=O)CO)C)O)C
Isomeric Smiles:	CCCC1O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@@]5([C@H]4[C@H](C[C@@]3([C@@]2(O1)C(=O)CO)C)O)C
Molecular Weight:	430.5
Molecular Formula:	C25H34O6

Compound Structure

2D Structure:

3D Structure:

Computed Properties

budesonide

Molecular Weight:	430.5
Molecular Formula:	C25H34O6
Hydrogen Bond Donor Count:	2
Hydrogen Bond Acceptor Count:	6
Rotatable Bond Count:	4
Heavy Atom Count:	31
Complexity:	862

Synonyms

budesonide

budesonide	budesonide
budesonide	Pulmicort
Rhinocort	Entocort
51333-22-3	Preferid
Rhinocort Aqua	Entocort EC
Pulmicort Respules	Budesonidum
Uceris	Budeson
Pulmicort Flexhaler	Cortivent
Micronyl	Respules
Spirocort	Bidien
S-1320	CHEBI:3207
MAP-0010	51372-29-3
MLS000028507	Budesonide MMX
Rhinocort alpha	(R)-Budesonide
16,17-Butylidenebis(oxy)-11,21-dihydroxypregna-1,4-diene-3,20-dione	(11beta,16alpha)-16,17-(Butylidenebis(oxy))-11,21-dihydroxypregna-1,4-diene-3,20-dione
Budenofalk	Budesonido
SMR000058337	Budecort Inhaler
(+)-16alpha,17alpha-Butylidenedioxy-11beta,21-dihydroxy-1,4-pregnadiene-3,20-dione	16A(R),17-(BUTYLIDENEBIS(OXY))-11B,21-DIHYDROXYPREGNA-1,4-DIENE-3,20-DIONE
Budesonidum INN-Latin	Budesonido INN-Spanish
Inflammide	Budiair
Miflonide	Pulmaxan
Fvolir	Budesonide USAN:INN:BAN:JAN
Rhinocort Allergy	Pulmaxan turbohaler
Pulmicort (TN)	Pulmicort Topinasal
Rhinocort (TN)	Pulmicort turbuhaler
Budesonide Easyhaler	S 1320
CCRIS 5230	Entocort EC (TN)
SR-01000000101	EINECS 257-139-7
Jorveza	Eltair
Ultesa	Noex
Giona Easyhaler	16?,17-(1RS)-Butylidenebis(oxy)-11?,21-dihydroxypregna-1,4-diene-3,20-dione
Pregna-1,4-diene-3,20-dione, 16,17-butylidenebis(oxy)-11,21-dihydroxy-, (11.beta.,16.alpha.)-	Prestwick_840
MFCD00083259	Uceris (TN)
(11-beta,16-alpha)-16,17-(Butylidenebis(oxy))-11,21-dihydroxypregna-1,4-diene-3,20-dione	16-alpha,17-alpha-Butylidenedioxy-11-beta,21-dihydroxy-1,4-pregnadiene-3,20-dione
(RS)-11beta,16alpha,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with butyraldehyde	Budesonide, >=99%
Opera_ID_1696	Prestwick0_000518
Prestwick1_000518	Prestwick2_000518
Prestwick3_000518	Epitope ID:161750
B 7777	SCHEMBL4096
CHEMBL1370	Pregna-1,4-diene-3,20-dione,16,17-(butylidenebis(oxy))-11,21-dihydroxy-, (11beta,16alpha)-
Lopac0_000174	BSPBio_000475
Budesonide (JAN/USP/INN)	MLS001077323
MLS002207112	SPBio_002396
BPBio1_000523	GTPL7434
DTXSID8020202	HSDB 8279
MAP0010	R01AD05
HMS1569H17	HMS2096H17
HMS2232D17	HMS3259H07
HMS3260D09	HMS3413B08
HMS3413P17	HMS3677B08
HMS3677P17	HMS3713H17
ACT03247	BCP05589
Eohilia (budesonide oral suspension)	Tox21_500174
BDBM50354850	AKOS015969655
AC-4697	ACN-043365
CCG-204269	CS-2063
DB01222	KS-1162
LP00174	NC00626
NSC 757788	SDCCGSBI-0050162.P002
11beta,21-dihydroxy-16alpha,17alpha-(butane-1,1-diyldioxy)pregna-1,4-diene-3,20-dione	NCGC00021318-05
NCGC00021318-06	NCGC00021318-08
NCGC00021318-18	NCGC00089747-04
NCGC00260859-01	BB164267
Budesonide 100 microg/mL in Acetonitrile	CPD000058337
HY-13580	Pregna-1,4-diene-3,20-dione, 16,17-(butylidenebis(oxy))-11,21-dihydroxy-, (11-beta,16-alpha)-
Pregna-1,4-diene-3,20-dione, 16,17-butylidenebis(oxy)-11,21-dihydroxy-, (11beta,16alpha(R))-, and 16alpha,17-((S)-Butylidenebis(oxy))-11beta,21-dihydroxypregna-1,4-diene-3,20-dione	B3909
EU-0100174	5301-EP2270008A1
5301-EP2280006A1	5301-EP2281563A1
5301-EP2281813A1	5301-EP2281815A1
5301-EP2281819A1	5301-EP2292617A1
5301-EP2292619A1	5301-EP2295402A2
5301-EP2295408A1	5301-EP2301933A1
5301-EP2305640A2	5301-EP2305659A1
5301-EP2308562A2	5301-EP2311818A1
5301-EP2311827A1	5301-EP2314590A1
5301-EP2316459A1	5301-EP2371811A2
D00246	T70986
333B223	Q422212
J-504150	Q-101375
SR-01000000101-2	SR-01000000101-6
BRD-A34299591-001-03-4	Budesonide, European Pharmacopoeia (EP) Reference Standard
Budesonide, United States Pharmacopeia (USP) Reference Standard	Budesonide, Pharmaceutical Secondary Standard; Certified Reference Material
(11?,16?)-16,17-Butylidenebis(oxy)-11,21-dihydroxypregna-1,4-diene-3,20-dione	(1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-6-propyl-5,7-dioxapentacyclo10.8.0.0^{2,9}.0^{4,8}.0^{13,18}icosa-14,17-dien-16-one
(4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-6b-Glycoloyl-5-hydroxy-4a,6a-dimethyl-8-propyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho2,1:4,5indeno1,2-d1,3dioxol-2-one"	(6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a-dimethyl-10-propyl-1,2,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-4H-naphtho2,1:4,5indeno1,2-d1,3dioxol-4-one"
(6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a-dimethyl-10-propyl-6a,6b,7,8,8a,8b,11a,12,12a,12b-decahydro-1H-naphtho2,1:4,5indeno1,2-d1,3dioxol-4(2H)-one"

Experimental Data

budesonide

Species	Dose	Unit	Control(Avg days)	Treatment(Avg days)	Avg/Med Lifespan Change(%)	Control(Max days)	Treatment(Max days)	Max Lifespan Change(%)	Significant	Strain	Gender	PubMed	Avg/Med Lifespan Change tab
Caenorhabditis elegans	33.000000000000000	umol/L			-8.000000000000000				NS	N2		24134630	Inactive

Experimental Data Visualization

budesonide

Statistics Data

budesonide

Species	Avg/Med Lifespan Change(%)	Max Lifespan Change(%)	Count Reference	Count Data point
Caenorhabditis elegans	-8.000000000000000		1	1

Statistics Data Visualization

budesonide

Compound Name:

budesonide

Compound CID:

5281004

Synonyms:

budesonide Pulmicort Rhinocort Entocort 51333-22-3 More...

Iupac Name:

(1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-6-propyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one

InChI:

InChI=1S/C25H34O6/c1-4-5-21-30-20-11-17-16-7-6-14-10-15(27)8-9-23(14,2)22(16)18(28)12-24(17,3)25(20,31-21)19(29)13-26/h8-10,16-18,20-22,26,28H,4-7,11-13H2,1-3H3/t16-,17-,18-,20+,21?,22+,23-,24-,25+/m0/s1

InChIKey:

VOVIALXJUBGFJZ-KWVAZRHASA-N

Canonical Smiles:

CCCC1OC2CC3C4CCC5=CC(=O)C=CC5(C4C(CC3(C2(O1)C(=O)CO)C)O)C

Isomeric Smiles:

CCCC1O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@@]5([C@H]4[C@H](C[C@@]3([C@@]2(O1)C(=O)CO)C)O)C

Molecular Weight:

430.5

Molecular Formula:

C25H34O6

Molecular Weight:

430.5

Molecular Formula:

C25H34O6

Hydrogen Bond Donor Count:

2

Hydrogen Bond Acceptor Count:

6

Rotatable Bond Count:

4

Heavy Atom Count:

31

Complexity:

862

budesonide

Pulmicort

Rhinocort

Entocort

51333-22-3

Preferid

Rhinocort Aqua

Entocort EC

Pulmicort Respules

Budesonidum

Uceris

Budeson

Pulmicort Flexhaler

Cortivent

Micronyl

Respules

Spirocort

Bidien

S-1320

CHEBI:3207

MAP-0010

51372-29-3

MLS000028507

Budesonide MMX

Rhinocort alpha

(R)-Budesonide

16,17-Butylidenebis(oxy)-11,21-dihydroxypregna-1,4-diene-3,20-dione

(11beta,16alpha)-16,17-(Butylidenebis(oxy))-11,21-dihydroxypregna-1,4-diene-3,20-dione

Budenofalk

Budesonido

SMR000058337

Budecort Inhaler

(+)-16alpha,17alpha-Butylidenedioxy-11beta,21-dihydroxy-1,4-pregnadiene-3,20-dione

16A(R),17-(BUTYLIDENEBIS(OXY))-11B,21-DIHYDROXYPREGNA-1,4-DIENE-3,20-DIONE

Budesonidum INN-Latin

Budesonido INN-Spanish

Inflammide

Budiair

Miflonide

Pulmaxan

Fvolir

Budesonide USAN:INN:BAN:JAN

Rhinocort Allergy

Pulmaxan turbohaler

Pulmicort (TN)

Pulmicort Topinasal

budesonide

Pulmicort

Rhinocort

Entocort

51333-22-3

More...