Compound Summary
beta-Nicotinamide mononucleotide
Compound Information
beta-Nicotinamide mononucleotide
Compound Name: | beta-Nicotinamide mononucleotide |
Compound CID: | 14180 |
Synonyms: | beta-Nicotinamide mononucleotide 1094-61-7 nicotinamide mononucleotide Nicotinamide ribotide nicotinamide nucleotide More... |
Iupac Name: | [(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate |
InChI: | InChI=1S/C11H15N2O8P/c12-10(16)6-2-1-3-13(4-6)11-9(15)8(14)7(21-11)5-20-22(17,18)19/h1-4,7-9,11,14-15H,5H2,(H3-,12,16,17,18,19)/t7-,8-,9-,11-/m1/s1 |
InChIKey: | DAYLJWODMCOQEW-TURQNECASA-N |
Canonical Smiles: | C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)[O-])O)O)C(=O)N |
Isomeric Smiles: | C1=CC(=C[N+](=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)[O-])O)O)C(=O)N |
Molecular Weight: | 334.22 |
Molecular Formula: | C11H15N2O8P |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
beta-Nicotinamide mononucleotide
Molecular Weight: | 334.22 |
Molecular Formula: | C11H15N2O8P |
Hydrogen Bond Donor Count: | 4 |
Hydrogen Bond Acceptor Count: | 8 |
Rotatable Bond Count: | 5 |
Heavy Atom Count: | 22 |
Complexity: | 455 |
Synonyms
beta-Nicotinamide mononucleotide
| beta-Nicotinamide mononucleotide | beta-Nicotinamide mononucleotide |
|---|---|
beta-Nicotinamide mononucleotide |
1094-61-7 |
nicotinamide mononucleotide |
Nicotinamide ribotide |
nicotinamide nucleotide |
beta-NMN |
beta-nicotinamide D-ribonucleotide |
nicotinamide ribonucleotide |
UNII-2KG6QX4W0V |
NMN |
nicotinamide D-ribonucleotide |
beta-Nicotinamide ribonucleotide |
3-(Aminocarbonyl)-1-(5-O-phosphonato-beta-D-ribofuranosyl)pyridinium |
2KG6QX4W0V |
CHEBI:16171 |
Pyridinium, 3-(aminocarbonyl)-1-(5-O-phosphono-beta-D-ribofuranosyl)-, inner salt |
((2R,3S,4R,5R)-5-(3-Carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogen phosphate |
NMN zwitterion |
3-(Aminocarbonyl)-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridinium inner salt |
MFCD00038748 |
EINECS 214-136-5 |
BETANMN |
b-NM |
Nicotinamidmononucleotid |
bmse000260 |
SCHEMBL105618 |
CHEMBL610238 |
B-NICOTINAMIDE MONONUCLEOTIDE |
EX-A3534 |
HY-F0004 |
BDBM50366763 |
AKOS015896881 |
CCG-267847 |
CS-4996 |
3-carbamoyl-1-beta-D-ribofuranosylpyridinium hydroxide 5-(dihydrogen phosphate) inner salt |
AC-35057 |
AS-59655 |
C00455 |
H11919 |
J-002287 |
Q21547155 |
3-carbamoyl-1-5-O-(hydroxyphosphinato)-beta-D-ribofuranosylpyridinium |
3-(aminocarbonyl)-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridinium, inner salt |
((2R,3S,4R,5R)-5-(3-carbamoylpyridinium-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogen phosphate |
3-carbamoyl-1-(2R,3R,4S,5R)-5-(hydrogen phosphonatooxy)methyl-3,4-dihydroxyoxolan-2-yl-1$l^{5}-pyridin-1-ylium |
3-carbamoyl-1-(2R,3R,4S,5R)-5-(hydrogen phosphonatooxy)methyl-3,4-dihydroxyoxolan-2-yl-1??-pyridin-1-ylium |
AfAEA centa notA inverted exclamation markAfasAA|AfAEAdaggeratrade markAfA centA centasA notA em leaderA inverted exclamation mark-Nicotinamide mononucleotide" |
Experimental Data
beta-Nicotinamide mononucleotide
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mus musculus | 100.000000000000000 | mg/kg | 0.000000000000000 | S | C57BL/6N | 28068222 | Active | ||||||
| Mus musculus | 300.000000000000000 | mg/kg | NS | C57BL/6N | 28068222 | Inactive | |||||||
| Drosophila melanogaster | 20.000000000000000 | umol/L | 47.840000000000000 | 47.840000000000000 | 0.000000000000000 | NS | FEMALES | 33008901 | Inactive | ||||
| Drosophila melanogaster | 200.000000000000000 | umol/L | 43.130000000000000 | 44.990000000000000 | 4.310000000000000 | NS | MALES | 33008901 | Inactive |
Experimental Data Visualization
beta-Nicotinamide mononucleotide
Statistics Data
beta-Nicotinamide mononucleotide
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Drosophila melanogaster | 4.310000000000000 | 1 | 2 | |
| Mus musculus | 0.000000000000000 | 1 | 2 |
Statistics Data Visualization
beta-Nicotinamide mononucleotide
