Compound Summary
baicalein
Compound Information
baicalein
Compound Name: | baicalein |
Compound CID: | 5281605 |
Synonyms: | baicalein 491-67-8 5,6,7-Trihydroxyflavone 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one Noroxylin More... |
Iupac Name: | 5,6,7-trihydroxy-2-phenylchromen-4-one |
InChI: | InChI=1S/C15H10O5/c16-9-6-11(8-4-2-1-3-5-8)20-12-7-10(17)14(18)15(19)13(9)12/h1-7,17-19H |
InChIKey: | FXNFHKRTJBSTCS-UHFFFAOYSA-N |
Canonical Smiles: | C1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C=C(C(=C3O)O)O |
Isomeric Smiles: | C1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C=C(C(=C3O)O)O |
Molecular Weight: | 270.24 |
Molecular Formula: | C15H10O5 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
baicalein
Molecular Weight: | 270.24 |
Molecular Formula: | C15H10O5 |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 1 |
Heavy Atom Count: | 20 |
Complexity: | 413 |
Synonyms
baicalein
| baicalein | baicalein |
|---|---|
baicalein |
491-67-8 |
5,6,7-Trihydroxyflavone |
5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one |
Noroxylin |
BaiKalein |
5,6,7-trihydroxy-2-phenylchromen-4-one |
Baicelein |
MFCD00017459 |
UNII-49QAH60606 |
NSC661431 |
CHEMBL8260 |
4H-1-Benzopyran-4-one, 5,6,7-trihydroxy-2-phenyl- |
5,6,7-trihydroxy-2-phenyl-chromen-4-one |
CHEBI:2979 |
49QAH60606 |
NSC-661431 |
5,7-Trihydroxyflavone |
Biacalein |
Sho-saiko-to |
SMR000112462 |
SR-01000597499 |
NSC 661431 |
Baicalein, 8 |
Baicalein,(S) |
3WL |
Baicalein, 14 |
Baicalein, 98% |
Spectrum_000427 |
Tocris-1761 |
SpecPlus_000758 |
Spectrum2_000466 |
Spectrum3_001608 |
Spectrum4_000537 |
Spectrum5_001418 |
Oprea1_765614 |
BSPBio_003215 |
KBioGR_001173 |
KBioSS_000907 |
MLS002473007 |
MLS006011756 |
BIDD:ER0121 |
DivK1c_006854 |
SCHEMBL139617 |
SPECTRUM1504002 |
5,6,7-Trihydroxy-2-phenyl-4H-1-benzopyran-4-one |
SPBio_000572 |
GTPL5144 |
DTXSID2022389 |
KBio1_001798 |
KBio2_000907 |
KBio2_003475 |
KBio2_006043 |
KBio3_002435 |
HMS1922O22 |
HMS2267F15 |
HMS3268C22 |
HMS3412F14 |
HMS3649O19 |
HMS3655P18 |
HMS3676F14 |
ALBB-028286 |
BCP14393 |
HY-N0196 |
TNP00121 |
ZINC3871633 |
BBL027840 |
BDBM50009001 |
CCG-38705 |
LMPK12111095 |
NSC729192 |
s2268 |
SBB067246 |
STL146746 |
AKOS005747014 |
AC-7991 |
CS-6159 |
MCULE-8669340472 |
NSC-729192 |
SDCCGMLS-0066744.P001 |
Baicalein, analytical reference material |
SMP1_000037 |
NCGC00017236-01 |
NCGC00017236-02 |
NCGC00017236-03 |
NCGC00017236-04 |
NCGC00017236-05 |
NCGC00017236-06 |
NCGC00017236-07 |
NCGC00017236-08 |
NCGC00017236-10 |
NCGC00017236-11 |
NCGC00025282-01 |
NCGC00025282-02 |
NCGC00025282-03 |
NCGC00025282-04 |
NCGC00178204-01 |
AS-57923 |
ST057152 |
SY057137 |
5,6,7-Trihydroxy-2-phenyl-chroman-4-one |
AB0018364 |
FT-0622548 |
N1858 |
SW219229-1 |
T2721 |
S00113 |
491B678 |
5,7-Trihydroxy-2-phenyl-4H-1-benzopyran-4-one |
A827663 |
Q-100550 |
Q2879363 |
SR-01000597499-1 |
SR-01000597499-3 |
SR-01000597499-4 |
SR-01000597499-6 |
W-202870 |
5,6,7-Trihydroxy-2-phenyl-(4H)-1-benzopyran-4-one |
BRD-K72327355-001-02-2 |
BRD-K72327355-001-06-3 |
Experimental Data
baicalein
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 50.000000000000000 | umol/L | 17.000000000000000 | Unclear | N2 | 33683565 | |||||||
| Caenorhabditis elegans | 25.000000000000000 | umol/L | 7.000000000000000 | Unclear | N2 | 33683565 | |||||||
| Caenorhabditis elegans | 100.000000000000000 | umol/L | Unclear | N2 | 33683565 | ||||||||
| Caenorhabditis elegans | 100.000000000000000 | umol/L | 6.000000000000000 | Unclear | N2 | 33683565 | |||||||
| Caenorhabditis elegans | 100.000000000000000 | umol/L | 39.000000000000000 | Unclear | N2 | 33683565 | |||||||
| Caenorhabditis elegans | 25.000000000000000 | umol/L | 14.330000000000000 | 16.980000000000000 | 18.490000000000000 | S | N2 | 33809299 | Active | ||||
| Caenorhabditis elegans | 100.000000000000000 | umol/L | 24.000000000000000 | S | N2 | 31201898 | Active | ||||||
| Caenorhabditis elegans | 100.000000000000000 | umol/L | 57.000000000000000 | 24.000000000000000 | S | N2 | 23339711 | Active | |||||
| Drosophila melanogaster | 0.040000000000000 | mg/mL | 37.990000000000000 | 41.230000000000000 | 0.090000000000000 | 57.900000000000000 | 61.200000000000000 | 0.060000000000000 | S | w1118 | 26778291 | Active | |
| Caenorhabditis elegans | 100.000000000000000 | umol/L | 14.330000000000000 | 14.960000000000000 | 4.400000000000000 | S | N2 | 33809299 | Active | ||||
| Caenorhabditis elegans | 50.000000000000000 | umol/L | 14.330000000000000 | 14.720000000000000 | 2.720000000000000 | NS | N2 | 33809299 | Inactive | ||||
| Caenorhabditis elegans | 100.000000000000000 | umol/L | 30.000000000000000 | S | N2 | 31201898 | Active | ||||||
| Caenorhabditis elegans | 10.000000000000000 | umol/L | 14.330000000000000 | 16.700000000000000 | 16.540000000000000 | S | N2 | 33809299 | Active | ||||
| Drosophila melanogaster | 1.000000000000000 | mg/mL | 37.990000000000000 | 41.530000000000000 | 0.090000000000000 | 57.900000000000000 | 60.600000000000000 | 0.050000000000000 | S | w1118 | 26778291 | Active | |
| Drosophila melanogaster | 0.200000000000000 | mg/mL | 37.990000000000000 | 45.510000000000000 | 0.200000000000000 | 57.900000000000000 | 60.200000000000000 | 0.040000000000000 | S | w1118 | 26778291 | Active |
Experimental Data Visualization
baicalein
Statistics Data
baicalein
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 57.000000000000000 | 39.000000000000000 | 4 | 12 |
| Drosophila melanogaster | 0.200000000000000 | 0.060000000000000 | 1 | 3 |
Statistics Data Visualization
baicalein
