Compound Summary
apigenin
Compound Information
apigenin
Compound Name: | apigenin |
Compound CID: | 5280443 |
Synonyms: | apigenin 520-36-5 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one Chamomile Versulin More... |
Iupac Name: | 5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one |
InChI: | InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-7,16-18H |
InChIKey: | KZNIFHPLKGYRTM-UHFFFAOYSA-N |
Canonical Smiles: | C1=CC(=CC=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O |
Isomeric Smiles: | C1=CC(=CC=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O |
Molecular Weight: | 270.24 |
Molecular Formula: | C15H10O5 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
apigenin
Molecular Weight: | 270.24 |
Molecular Formula: | C15H10O5 |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 1 |
Heavy Atom Count: | 20 |
Complexity: | 411 |
Synonyms
apigenin
| apigenin | apigenin |
|---|---|
apigenin |
520-36-5 |
5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one |
Chamomile |
Versulin |
Apigenol |
4,5,7-Trihydroxyflavone |
Spigenin |
Apigenine |
C.I. Natural Yellow 1 |
Pelargidenon 1449 |
5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one |
5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone |
5,7,4-Trihydroxyflavone |
5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
NSC 83244 |
2-(p-Hydroxyphenyl)-5,7-dihydroxychromone |
4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)- |
UCCF 031 |
UNII-7V515PI7F6 |
FLAVONE, 4,5,7-TRIHYDROXY- |
CHEBI:18388 |
4′,5,7-Trihydroxyflavone |
CHEMBL28 |
MFCD00006831 |
7V515PI7F6 |
NSC83244 |
NSC-83244 |
CAS-520-36-5 |
ST056301 |
DSSTox_CID_2391 |
DSSTox_RID_76568 |
DSSTox_GSID_22391 |
8002-66-2 |
4,5,7-Trihydroxyflavone;Apigenol;C.I. Natural Yellow 1 |
SMR000326850 |
CCRIS 3789 |
SR-01000075663 |
EINECS 208-292-3 |
BRN 0262620 |
Pelargidenone |
Matricaria oil |
Chamomile Powder |
HSDB 7573 |
4der |
4dgm |
4hkk |
Naringenin, 18 |
Prestwick_719 |
Apigenin, 13 |
Tocris-1227 |
3cf9 |
4,7-Trihydroxyflavone |
BiomolKI_000078 |
Prestwick0_000414 |
Prestwick1_000414 |
Prestwick2_000414 |
Prestwick3_000414 |
Spectrum2_000428 |
Spectrum3_001882 |
Spectrum4_001999 |
Lopac-A-3145 |
BiomolKI2_000082 |
4,5, 7-Trihydroxyflavone |
Lopac0_000065 |
Oprea1_622293 |
SCHEMBL19428 |
4,5,7-trihydroxy-Flavone |
Apigenin, analytical standard |
BSPBio_000368 |
BSPBio_003384 |
KBioGR_002565 |
SPECTRUM200846 |
5-18-04-00574 (Beilstein Handbook Reference) |
MLS000697626 |
MLS000859991 |
MLS001074874 |
MLS006011839 |
BIDD:ER0135 |
DivK1c_000798 |
SCHEMBL222227 |
SPBio_000416 |
SPBio_002307 |
ghl.PD_Mitscher_leg0.1194 |
BDBM7458 |
BPBio1_000406 |
GTPL4136 |
MEGxp0_000176 |
DTXSID6022391 |
ACon1_002450 |
cid_5280443 |
HMS502H20 |
KBio1_000798 |
KBio3_002887 |
NINDS_000798 |
Bio1_000376 |
Bio1_000865 |
Bio1_001354 |
HMS1569C10 |
HMS1922P22 |
HMS2096C10 |
HMS2230D17 |
HMS3260M11 |
HMS3267D21 |
HMS3373B18 |
HMS3412A08 |
HMS3561P09 |
HMS3655D18 |
HMS3676A08 |
HMS3866D03 |
Apigenin, >=95.0% (HPLC) |
4,5,7-Trihydroxyflavone, 97% |
ACN-S003241 |
BCP28288 |
HY-N1201 |
ZINC3871576 |
Tox21_201542 |
Tox21_302884 |
Tox21_500065 |
Apigenin; 4,5,7-Trihydroxyflavone |
BBL010499 |
CCG-40061 |
HSCI1_000221 |
LMPK12110005 |
s2262 |
SBB066087 |
STK801630 |
ZB1873 |
AKOS002140699 |
AC-8011 |
ACN-034762 |
CS-5432 |
DB07352 |
EBD2138579 |
LP00065 |
MCULE-6141069907 |
ND-9076 |
SDCCGMLS-0066379.P001 |
SDCCGSBI-0050053.P003 |
IDI1_000798 |
SMP2_000338 |
Apigenin, >=97% (TLC), from citrus |
NCGC00015049-01 |
NCGC00015049-02 |
NCGC00015049-03 |
NCGC00015049-04 |
NCGC00015049-05 |
NCGC00015049-06 |
NCGC00015049-07 |
NCGC00015049-08 |
NCGC00015049-09 |
NCGC00015049-10 |
NCGC00015049-11 |
NCGC00015049-12 |
NCGC00015049-13 |
NCGC00015049-14 |
NCGC00015049-15 |
NCGC00015049-16 |
NCGC00015049-18 |
NCGC00015049-28 |
NCGC00025057-01 |
NCGC00025057-02 |
NCGC00025057-03 |
NCGC00025057-04 |
NCGC00025057-05 |
NCGC00025057-06 |
NCGC00025057-07 |
NCGC00025057-08 |
NCGC00025057-09 |
NCGC00169835-01 |
NCGC00169835-02 |
NCGC00169835-03 |
NCGC00256419-01 |
NCGC00259092-01 |
NCGC00260750-01 |
NCI60_041830 |
SY005957 |
TS-00897 |
AB0010536 |
LY 080400 |
EU-0100065 |
FT-0622445 |
FT-0623582 |
FT-0662251 |
N1828 |
SW196866-2 |
20A365 |
A 3145 |
C01477 |
J10341 |
K00045 |
O11338 |
Apigenin, >=97% (TLC), from parsley, powder |
Biochem Biophys Res Comm 212: 767 (1997) |
5,7-dihydroxy-2-(4-hydroxyphenyl)-chromen-4-one |
A828903 |
Apigenin, primary pharmaceutical reference standard |
Q424567 |
4 inverted exclamation mark ,5,7-trihydroxyflavone |
Q-100586 |
Q-200822 |
SR-01000075663-1 |
SR-01000075663-3 |
SR-01000075663-7 |
SR-01000075663-8 |
BRD-K01493881-001-10-4 |
BRD-K01493881-001-17-9 |
5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one # |
4H-1-Benzopyran-4-one,7-dihydroxy-2-(4-hydroxyphenyl)- |
D50A2D8A-6D8B-4708-B21E-2DE9580D033F |
Apigenin, United States Pharmacopeia (USP) Reference Standard |
4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)- (9CI) |
Experimental Data
apigenin
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 50.000000000000000 | umol/L | -1.900000000000000 | NS | N2 | 30970250 | Inactive | ||||||
| Caenorhabditis elegans | 100.000000000000000 | umol/L | 0.000000000000000 | S | N2 | 32334190 | Active | ||||||
| Caenorhabditis elegans | 33.000000000000000 | umol/L | 3.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
apigenin
Statistics Data
apigenin
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 3.000000000000000 | 3 | 3 |
Statistics Data Visualization
apigenin
