Compound Summary
amiprilose
Compound Information
amiprilose
Compound Name: | amiprilose |
Compound CID: | 9798098 |
Synonyms: | amiprilose Therafectin AMIPRILOSE HYDROCHLORIDE UNII-546994B3VA 56824-20-5 More... |
Iupac Name: | (1R)-1-[(3aR,5R,6S,6aR)-6-[3-(dimethylamino)propoxy]-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl]ethane-1,2-diol;hydrochloride |
InChI: | InChI=1S/C14H27NO6.ClH/c1-14(2)20-12-11(18-7-5-6-15(3)4)10(9(17)8-16)19-13(12)21-14;/h9-13,16-17H,5-8H2,1-4H3;1H/t9-,10-,11+,12-,13-;/m1./s1 |
InChIKey: | RJNRORZRFGUAKL-ADMBVFOFSA-N |
Canonical Smiles: | CC1(OC2C(C(OC2O1)C(CO)O)OCCCN(C)C)C.Cl |
Isomeric Smiles: | CC1(O[C@@H]2[C@H]([C@H](O[C@@H]2O1)[C@@H](CO)O)OCCCN(C)C)C.Cl |
Molecular Weight: | 341.83 |
Molecular Formula: | C14H28ClNO6 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
amiprilose
Molecular Weight: | 341.83 |
Molecular Formula: | C14H28ClNO6 |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 7 |
Rotatable Bond Count: | 7 |
Heavy Atom Count: | 22 |
Complexity: | 337 |
Synonyms
amiprilose
| amiprilose | amiprilose |
|---|---|
amiprilose |
Therafectin |
AMIPRILOSE HYDROCHLORIDE |
UNII-546994B3VA |
56824-20-5 |
60414-06-4 |
Amiprilose hydrochloride USAN |
Amiprilosehydrochloride |
546994B3VA |
Amiprilose hydrochloride (USAN) |
Amiprilose HCl |
a-D-Glucofuranose,3-O-3-(dimethylamino)propyl-1,2-O-(1-methylethylidene)- |
Therafectin (TN) |
SM-1213 (Free base) |
MLS002154029 |
CHEMBL1256946 |
SM -1213 (FREE BASE) |
AKOS015845775 |
AKOS016010143 |
CCG-220845 |
3-O-(3-(Dimethylamino)propyl)-1,2-O-isopropylidene-alpha-D-glucofuranose hydrochloride |
SMR001233356 |
D02911 |
414A064 |
Q27261179 |
ETHYL5,7-DICHLORO-4-HYDROXYQUINOLINE-3-CARBOXYLATE |
alpha-D-Glucofuranose, 3-O-(3-(dimethylamino)propyl)-1,2-O-(1-methylethylidene)-, hydrochloride |
Experimental Data
amiprilose
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -6.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
amiprilose
Statistics Data
amiprilose
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -6.000000000000000 | 1 | 1 |
Statistics Data Visualization
amiprilose
