Compound Summary
amifostine
Compound Information
amifostine
Compound Name: | amifostine |
Compound CID: | 2141 |
Synonyms: | amifostine 20537-88-6 Ethiofos Gammaphos Ethyol More... |
Iupac Name: | 2-(3-aminopropylamino)ethylsulfanylphosphonic acid |
InChI: | InChI=1S/C5H15N2O3PS/c6-2-1-3-7-4-5-12-11(8,9)10/h7H,1-6H2,(H2,8,9,10) |
InChIKey: | JKOQGQFVAUAYPM-UHFFFAOYSA-N |
Canonical Smiles: | C(CN)CNCCSP(=O)(O)O |
Isomeric Smiles: | C(CN)CNCCSP(=O)(O)O |
Molecular Weight: | 214.23 |
Molecular Formula: | C5H15N2O3PS |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
amifostine
Molecular Weight: | 214.23 |
Molecular Formula: | C5H15N2O3PS |
Hydrogen Bond Donor Count: | 4 |
Hydrogen Bond Acceptor Count: | 6 |
Rotatable Bond Count: | 7 |
Heavy Atom Count: | 12 |
Complexity: | 152 |
Synonyms
amifostine
| amifostine | amifostine |
|---|---|
amifostine |
20537-88-6 |
Ethiofos |
Gammaphos |
Ethyol |
Sapep |
Apaetp |
Aminopropylaminoethyl thiophosphate |
NSC-296961 |
WR 2721 |
YM-08310 |
2-(3-Aminopropylamino)ethyl thiophosphate |
AU-95722 |
UNII-ILA426L95O |
NSC296961 |
WR2721 |
Amifostine (Hydrate) |
NSC 296961 |
WR-2721 |
2-(3-aminopropylamino)ethylsulfanylphosphonic acid |
S-(2-(3-Aminopropylamino)ethyl) phosphorothioate |
CHEBI:2636 |
ILA426L95O |
WR 2721C |
Amifostina |
NCGC00015073-02 |
S-(2-((3-Aminopropyl)amino)ethyl) dihydrogen phosphorothioate |
Ethanethiol, 2-(3-aminopropyl)amino-, 1-(dihydrogen phosphate) |
2-((3-Aminopropyl)amino)-ethanethiol, dihydrogen phosphate ester (9CI) |
DSSTox_CID_2585 |
Ethiofos Anhydrous |
DSSTox_RID_76644 |
DSSTox_GSID_22585 |
C5H15N2O3PS |
({2-(3-aminopropyl)aminoethyl}sulfanyl)phosphonic acid |
S-{2-(3-aminopropyl)aminoethyl} dihydrogen thiophosphate |
Amifostine Ethiofos |
Amifostine Anhydrous |
Amifostine USAN:INN:BAN |
CAS-20537-88-6 |
S-2-(3-Aminopropylamino)ethyl phosphorothioate |
SR-01000075680 |
BRN 2088122 |
YM 08310 |
S-2-(3-Aminopropyl)aminoethyl dihydrogen phosphorothioate |
CCRIS 9316 |
HSDB 7560 |
Amifostine,(S) |
S,2-(3-Aminopropylamino)ethyl-phosphorothioic acid |
S-2-(3-Aminopropylamino)ethyl phosphorothioic acid |
Ethyol;WR2721 |
Spectrum_000332 |
S-omega-(3-Aminopropylamino)ethyl dihydrogen phosphorothioate |
SpecPlus_000647 |
2-(3-Aminopropyl)aminoethylphosphorothioate |
Acide ((amino-3 propylamino)-2 ethyl)-S-phosphorothioique French |
Spectrum5_001920 |
Lopac-A-5922 |
Ethanethiol, 2-((3-aminopropyl)amino)-, dihydrogen phosphate (ester) |
NCIMech_000622 |
S 8744 |
CHEMBL1006 |
Lopac0_000029 |
SCHEMBL18464 |
KBioSS_000812 |
cc-307 |
MLS000028473 |
S-2-(3-aminopropylamino)-ethylphosphorothioic acid |
BIDD:GT0059 |
DivK1c_006743 |
WR-2721 TRIHYDRATE |
DTXSID8022585 |
KBio1_001687 |
KBio2_000812 |
KBio2_003380 |
KBio2_005948 |
Acide ((amino-3 propylamino)-2 ethyl)-S-phosphorothioique |
HMS2090I03 |
HMS3260E19 |
HMS3713C06 |
Pharmakon1600-01503081 |
Phosphorothioic acid, S-(2-(3-aminopropylamino)ethyl) ester |
BCP08957 |
HY-B0639 |
Phosphorothioic acid, S-2-(3-aminopropyl)aminoethyl ester |
Tox21_110077 |
Tox21_500029 |
CCG-35734 |
MFCD00233058 |
NSC758236 |
ZINC21992285 |
AKOS015895196 |
Tox21_110077_1 |
AC-1126 |
DB01143 |
LP00029 |
NSC-758236 |
SDCCGSBI-0050018.P005 |
SMP2_000335 |
NCGC00015073-01 |
NCGC00015073-03 |
NCGC00015073-04 |
NCGC00015073-05 |
NCGC00015073-15 |
NCGC00093549-01 |
NCGC00093549-02 |
NCGC00260714-01 |
AS-13020 |
Ethanethiol, dihydrogen phosphate (ester) |
NCI60_002485 |
SMR000058413 |
Ethanethiol, dihydrogen phosphate- (ester) |
SBI-0050018.P003 |
AB0012846 |
EU-0100029 |
FT-0622272 |
37A886 |
A 5922 |
C06819 |
33870-EP2275420A1 |
33870-EP2295055A2 |
33870-EP2295416A2 |
33870-EP2295426A1 |
33870-EP2295427A1 |
33870-EP2298748A2 |
33870-EP2298764A1 |
33870-EP2298765A1 |
33870-EP2305642A2 |
33870-EP2311453A1 |
33870-EP2311808A1 |
33870-EP2311829A1 |
AB00053311-04 |
AB00053311-05 |
AB00053311_06 |
A814662 |
Q251698 |
{S-2-(3-Aminopropylamino)ethyl} phosphorothioate |
J-013390 |
J-519582 |
SR-01000075680-1 |
SR-01000075680-3 |
SR-01000075680-5 |
2-(3-Aminopropyl)aminoethyl phosphorothioate; WR2721 |
BRD-K73947551-001-01-0 |
2-(3-aminopropyl)aminoethanethiol dihydrogen phosphate |
2-(3-aminopropylamino)ethylsulfanylphosphonic acid,trihydrate |
2-(3-aminopropylamino)ethylsulfanylphosphonic acid;Amifostine |
Phosphorothioic acid, S-2-(3-aminopropyl)aminoethylester |
S-2-(3-aminopropylamino)ethyl O,O-dihydrogen phosphorothioate |
{S-2-(3-Aminopropyl)aminoethyl} dihydrogen phosphorothioate |
Ethanethiol, {S-(3-aminopropyl)amino-,} dihydrogen phosphate- (ester) |
Experimental Data
amifostine
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -4.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
amifostine
Statistics Data
amifostine
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -4.000000000000000 | 1 | 1 |
Statistics Data Visualization
amifostine
