Compound Summary
actinonin
Compound Information
actinonin
Compound Name: | actinonin |
Compound CID: | 443600 |
Synonyms: | actinonin Actinonine 13434-13-4 UNII-P18SPA8N0K P18SPA8N0K More... |
Iupac Name: | (2R)-N'-hydroxy-N-[(2S)-1-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]-2-pentylbutanediamide |
InChI: | InChI=1S/C19H35N3O5/c1-4-5-6-8-14(11-16(24)21-27)18(25)20-17(13(2)3)19(26)22-10-7-9-15(22)12-23/h13-15,17,23,27H,4-12H2,1-3H3,(H,20,25)(H,21,24)/t14-,15+,17+/m1/s1 |
InChIKey: | XJLATMLVMSFZBN-VYDXJSESSA-N |
Canonical Smiles: | CCCCCC(CC(=O)NO)C(=O)NC(C(C)C)C(=O)N1CCCC1CO |
Isomeric Smiles: | CCCCC[C@H](CC(=O)NO)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1CO |
Molecular Weight: | 385.5 |
Molecular Formula: | C19H35N3O5 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
actinonin
Molecular Weight: | 385.5 |
Molecular Formula: | C19H35N3O5 |
Hydrogen Bond Donor Count: | 4 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 11 |
Heavy Atom Count: | 27 |
Complexity: | 498 |
Synonyms
actinonin
| actinonin | actinonin |
|---|---|
actinonin |
Actinonine |
13434-13-4 |
UNII-P18SPA8N0K |
P18SPA8N0K |
CHEMBL308333 |
(R)-N4-hydroxy-N1-((S)-1-((S)-2-(hydroxymethyl)pyrrolidin-1-yl)-3-methyl-1-oxobutan-2-yl)-2-pentylsuccinamide |
2-(FORMYL-HYDROXY-AMINO)-METHYL-HEPTANOIC ACID 1-(2-HYDROXYMETHYL-PYRROLIDINE-1-CARBONYL)-2-METHYL-PROPYL-AMIDE |
Octanohydroxamic acid, 3-((1-((2-(hydroxymethyl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)carbamoyl)- |
(-)-actinonin |
BB2 |
SR-01000075681 |
(?)-Actinonin |
3g5k |
3m6p |
3m6q |
3m6r |
3pn4 |
4dr9 |
4je7 |
Spectrum2_000628 |
Spectrum3_000680 |
Spectrum4_001932 |
Spectrum5_000728 |
Lopac0_000010 |
BSPBio_002379 |
KBioGR_002305 |
DivK1c_001024 |
SCHEMBL279450 |
SPBio_000596 |
HMS503M09 |
KBio1_001024 |
KBio3_001599 |
DTXSID70928580 |
NINDS_001024 |
HMS3260A21 |
(2R)-2-2-(hydroxyamino)-2-oxo-ethyl-N-(1S)-1-(2S)-2-(hydroxymethyl)pyrrolidine-1-carbonyl-2-methyl-propylheptanamide |
N*4*-Hydroxy-N*1*-1-(2-hydroxymethyl-pyrrolidine-1-carbonyl)-2-methyl-propyl-2-pentyl-succinamide |
ZINC3979014 |
Tox21_500010 |
BDBM50089194 |
CCG-38543 |
AKOS015894413 |
DB04310 |
LP00010 |
SDCCGSBI-0049999.P004 |
IDI1_001024 |
NCGC00093535-01 |
NCGC00093535-02 |
NCGC00093535-03 |
NCGC00093535-04 |
NCGC00093535-07 |
NCGC00260695-01 |
(2R)-N-hydroxy-N-(2S)-1-(2S)-2-(hydroxymethyl)pyrrolidin-1-yl-3-methyl-1-oxobutan-2-yl-2-pentylbutanediamide |
Butanediamide, N4-hydroxy-N1-(1-((2-(hydroxymethyl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)-2-pentyl-, stereoisomer |
HY-113952 |
CS-0064758 |
EU-0100010 |
A 6671 |
Q4676979 |
SR-01000075681-1 |
SR-01000075681-5 |
Actinonin in combination with isoniazid and rifampicin |
BRD-K24621118-001-02-5 |
BRD-K24621118-001-03-3 |
(2R)-N~4~-hydroxy-N~1~-(1S)-1-{(2S)-2-(hydroxymethyl)pyrrolidin-1-ylcarbonyl}-2-methylpropyl-2-pentylbutanediamide |
(R)-N*4*-Hydroxy-N*1*-(S)-1-((S)-2-hydroxymethyl-pyrrolidine-1-carbonyl)-2-methyl-propyl-2-pentyl-succinamide |
N*4*-Hydroxy-N*1*-(S)-1-((S)-2-hydroxymethyl-pyrrolidine-1-carbonyl)-2-methyl-propyl-2-(R)-pentyl-succinamide |
Experimental Data
actinonin
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -2.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
actinonin
Statistics Data
actinonin
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -2.000000000000000 | 1 | 1 |
Statistics Data Visualization
actinonin
