Compound Summary
Ziprasidone hydrochloride
Compound Information
Ziprasidone hydrochloride
Compound Name: | Ziprasidone hydrochloride |
Compound CID: | 219099 |
Synonyms: | Ziprasidone hydrochloride 122883-93-6 Ziprasidone HCl Geodon Zeldox More... |
Iupac Name: | 5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1,3-dihydroindol-2-one;hydrochloride |
InChI: | InChI=1S/C21H21ClN4OS.ClH/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21;/h1-4,11,13H,5-10,12H2,(H,23,27);1H |
InChIKey: | NZDBKBRIBJLNNT-UHFFFAOYSA-N |
Canonical Smiles: | C1CN(CCN1CCC2=C(C=C3C(=C2)CC(=O)N3)Cl)C4=NSC5=CC=CC=C54.Cl |
Isomeric Smiles: | C1CN(CCN1CCC2=C(C=C3C(=C2)CC(=O)N3)Cl)C4=NSC5=CC=CC=C54.Cl |
Molecular Weight: | 449.4 |
Molecular Formula: | C21H22Cl2N4OS |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Ziprasidone hydrochloride
Molecular Weight: | 449.4 |
Molecular Formula: | C21H22Cl2N4OS |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 29 |
Complexity: | 573 |
Synonyms
Ziprasidone hydrochloride
| Ziprasidone hydrochloride | Ziprasidone hydrochloride |
|---|---|
Ziprasidone hydrochloride |
122883-93-6 |
Ziprasidone HCl |
Geodon |
Zeldox |
5-(2-(4-(Benzodisothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one hydrochloride |
Ziprasidone (hydrochloride) |
UNII-JAL53626GG |
5-2-4-(1,2-Benzisothiazol-3-yl)-1-piperazinylethyl-6-chloro-1,3-dihydro-2H-indol-2-one hydrochloride |
5-2-4-(1,2-Benzisothiazol-3yl)-1-piperazinylethyl-6-chloro-1,3-dihydro-2H-indol-2-one hydrochloride |
JAL53626GG |
5-2-4-(1,2-benzothiazol-3-yl)piperazin-1-ylethyl-6-chloro-1,3-dihydroindol-2-one hydrochloride |
CP 88059 (hydrochloride monohydrate) |
122883-93-6 (HCl) |
C21H22Cl2N4OS |
5-{2-4-(1,2-benzothiazol-3-yl)piperazin-1-ylethyl}-6-chloro-2,3-dihydro-1H-indol-2-one hydrochloride |
CP 88059 |
Ziprasidone hydrochloride USAN |
ZIPRASIDONE HYDROCHLORIDE HYDRATE |
C21H21ClN4OS.HCl |
CP-88059-1 |
Ziprasidone, HCl |
CP-88059 hydrochloride |
CHEMBL1712 |
MLS006010221 |
SCHEMBL122876 |
DTXSID00153762 |
HY-14542A |
s1444 |
AKOS015848366 |
AC-7053 |
CCG-220561 |
CS-1887 |
KS-1219 |
2H-Indol-2-one, 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)ethyl)-6-chloro-1,3-dihydro-, monohydrochloride |
5-2-4-(1,2-benzothiazol-3-yl)piperazin-1-ylethyl-6-chloro-1,3-dihydroindol-2-one;hydrochloride |
AC-26998 |
H485 |
SMR002204092 |
AB0013070 |
SW199027-2 |
X9542 |
939Z277 |
A890906 |
SR-01000759387 |
SR-01000759387-2 |
Q27281411 |
5-(2-(4-(BENZODISOTHIAZOL-3-YL)PIPERAZIN-1-YL)ETHYL)-6-CHLOROINDOLIN-2-ONE HCL |
2H-Indol-2-one, 5-2-4-(1,2-benzisothiazol-3-yl)-1-piperazinylethyl-6-chloro-1,3-dihydro-, hydrochloride (1:1) |
5-(2-(4-(Benzodisothiazol-3-yl)piperazin-1-yl)-ethyl)-6-chloroindolin-2-one hydrochloride |
5-2-4-(1,2-Benzisothiazol-3-yl)-1 -piperazinylethyl-6-chloro-1,3-dihydro-2H-indol- 2-one hydrochloride |
5-2-4-(1,2-benzisothiazol-3-yl)-1-piperazinylethyl-6-chloro-1, 3-dihydro-2h-indol-2-one hydrochloride |
Ziprasidone hydrochloride solution, 1.0 mg/mL in methanol, certified reference material, ampule of 1 mL |
Experimental Data
Ziprasidone hydrochloride
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drosophila melanogaster | 200.000000000000000 | umol/L | 46.640000000000000 | 44.940000000000000 | -3.653000000000000 | NS | MALES | 33008901 | Inactive | ||||
| Drosophila melanogaster | 20.000000000000000 | umol/L | 46.240000000000000 | 48.820000000000000 | 5.598000000000000 | NS | FEMALES | 33008901 | Inactive |
Experimental Data Visualization
Ziprasidone hydrochloride
Statistics Data
Ziprasidone hydrochloride
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Drosophila melanogaster | 5.598000000000000 | 1 | 2 |
Statistics Data Visualization
Ziprasidone hydrochloride
