Compound Summary
ZD 7114 hydrochloride
Compound Information
ZD 7114 hydrochloride
Compound Name: | ZD 7114 hydrochloride |
Compound CID: | 9890216 |
Synonyms: | ZD 7114 hydrochloride 129689-28-7 ICI D7114 UNII-Z63T1D9750 Z63T1D9750 More... |
Iupac Name: | 2-[4-[2-[[(2S)-2-hydroxy-3-phenoxypropyl]amino]ethoxy]phenoxy]-N-(2-methoxyethyl)acetamide;hydrochloride |
InChI: | InChI=1S/C22H30N2O6.ClH/c1-27-13-12-24-22(26)17-30-21-9-7-20(8-10-21)28-14-11-23-15-18(25)16-29-19-5-3-2-4-6-19;/h2-10,18,23,25H,11-17H2,1H3,(H,24,26);1H/t18-;/m0./s1 |
InChIKey: | KCAMZVQSGDBGGF-FERBBOLQSA-N |
Canonical Smiles: | COCCNC(=O)COC1=CC=C(C=C1)OCCNCC(COC2=CC=CC=C2)O.Cl |
Isomeric Smiles: | COCCNC(=O)COC1=CC=C(C=C1)OCCNC[C@@H](COC2=CC=CC=C2)O.Cl |
Molecular Weight: | 454.9 |
Molecular Formula: | C22H31ClN2O6 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
ZD 7114 hydrochloride
Molecular Weight: | 454.9 |
Molecular Formula: | C22H31ClN2O6 |
Hydrogen Bond Donor Count: | 4 |
Hydrogen Bond Acceptor Count: | 7 |
Rotatable Bond Count: | 15 |
Heavy Atom Count: | 31 |
Complexity: | 439 |
Synonyms
ZD 7114 hydrochloride
| ZD 7114 hydrochloride | ZD 7114 hydrochloride |
|---|---|
ZD 7114 hydrochloride |
129689-28-7 |
ICI D7114 |
UNII-Z63T1D9750 |
Z63T1D9750 |
(S)-4-2-HYDROXY-3-PHENOXYPROPYLAMINOETHOXY-N-(2-METHOXYETHYL)PHENOXYACETAMIDE HYDROCHLORIDE |
(S)-2-(4-(2-((2-Hydroxy-3-phenoxypropyl)amino)ethoxy)phenoxy)-N-(2-methoxyethyl)acetamide hydrochloride |
2-4-2-(2S)-2-hydroxy-3-phenoxypropylaminoethoxyphenoxy-N-(2-methoxyethyl)acetamide;hydrochloride |
129689-30-1 |
zd7114 hydrochloride |
D-7114 hydrochloride |
ZD-7114 hydrochloride |
SCHEMBL2343849 |
DTXSID90432437 |
AKOS022180623 |
CCG-221889 |
ZD 7114 hydrochloride, >=98% (HPLC) |
B6509 |
J-005700 |
(S)-4-2-Hydroxy-3-phenoxypropylaminoethoxy-N-(2methoxyethyl)phenoxyacetamide hydrochloride |
(S)-2-(4-(2-(2-hydroxy-3-phenoxypropylamino)ethoxy)phenoxy)-N-(2-methoxyethyl)acetamide hydrochloride |
(S)-4-2-(2-hydroxy-3-phenoxypropylamino)ethoxy-N-(2-methoxyethyl)phenoxyacetamide hydrochloride |
Acetamide, 2-(4-(2-((2-hydroxy-3-phenoxypropyl)amino)ethoxy)phenoxy)-N-(2-methoxyethyl)-, monohydrochloride, (S)- |
Experimental Data
ZD 7114 hydrochloride
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 100.000000000000000 | umol/L | 17.250000000000000 | 18.460000000000000 | 7.001000000000000 | NS | N2 | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 10.000000000000000 | umol/L | 16.600000000000000 | 16.700000000000000 | 0.574900000000000 | NS | N2 | 33008901 | Inactive |
Experimental Data Visualization
ZD 7114 hydrochloride
Statistics Data
ZD 7114 hydrochloride
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 7.001000000000000 | 1 | 2 |
Statistics Data Visualization
ZD 7114 hydrochloride
