Compound Summary
Y-27632 dihydrochloride
Compound Information
Y-27632 dihydrochloride
Compound Name: | Y-27632 dihydrochloride |
Compound CID: | 9901617 |
Synonyms: | Y-27632 dihydrochloride 129830-38-2 Y-27632 2HCl Y 27632 dihydrochloride (1R,4r)-4-((R)-1-aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamide dihydrochloride More... |
Iupac Name: | 4-[(1R)-1-aminoethyl]-N-pyridin-4-ylcyclohexane-1-carboxamide;dihydrochloride |
InChI: | InChI=1S/C14H21N3O.2ClH/c1-10(15)11-2-4-12(5-3-11)14(18)17-13-6-8-16-9-7-13;;/h6-12H,2-5,15H2,1H3,(H,16,17,18);2*1H/t10-,11?,12?;;/m1../s1 |
InChIKey: | IDDDVXIUIXWAGJ-DDSAHXNVSA-N |
Canonical Smiles: | CC(C1CCC(CC1)C(=O)NC2=CC=NC=C2)N.Cl.Cl |
Isomeric Smiles: | C[C@H](C1CCC(CC1)C(=O)NC2=CC=NC=C2)N.Cl.Cl |
Molecular Weight: | 320.3 |
Molecular Formula: | C14H23Cl2N3O |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Y-27632 dihydrochloride
Molecular Weight: | 320.3 |
Molecular Formula: | C14H23Cl2N3O |
Hydrogen Bond Donor Count: | 4 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 3 |
Heavy Atom Count: | 20 |
Complexity: | 268 |
Synonyms
Y-27632 dihydrochloride
| Y-27632 dihydrochloride | Y-27632 dihydrochloride |
|---|---|
Y-27632 dihydrochloride |
129830-38-2 |
Y-27632 2HCl |
Y 27632 dihydrochloride |
(1R,4r)-4-((R)-1-aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamide dihydrochloride |
Y-27632 (dihydrochloride) |
Y27632 2HCl |
UNII-Q9828II7F3 |
Y27632 |
Q9828II7F3 |
trans-4-((R)-1-aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamide dihydrochloride |
trans-4-(1R)-1-Aminoethyl-N-4-pyridinylcyclohexanecarboxamide dihydrochloride |
(1R,4r)-4-((R)-1-aminoethyl)-N-(pyridin-4-yl)cyclohexane-1-carboxamide dihydrochloride |
Y 27632 hydrochloride |
Y 27632 HCl |
(R)-(+)-trans-4-(1-Aminoethyl)-N-(4-Pyridyl)cyclohexanecarboxamide dihydrochloride |
InSolution Y-27632 |
cc-26 |
Rock inhibitor y-27632 |
C14H21N3O.2ClH |
SCHEMBL819701 |
SCHEMBL819702 |
CHEMBL536267 |
TB1254-GMP |
CHEMBL1605605 |
DTXSID3042635 |
AOB3877 |
EX-A423 |
4-(1R)-1-aminoethyl-N-pyridin-4-ylcyclohexane-1-carboxamide;dihydrochloride |
EX-A3440 |
WFA98650 |
Tox21_500333 |
MFCD03490488 |
AKOS024456492 |
CCG-100675 |
CS-0878 |
Cyclohexanecarboxamide, 4-(1R)-1-aminoethyl-N-4-pyridinyl-, hydrochloride (1:2), trans- |
NCGC00092276-01 |
NCGC00093773-01 |
NCGC00261018-01 |
AS-74311 |
BY162499 |
HY-10583 |
AB0033836 |
S1049 |
SW219086-1 |
X7611 |
Y-27632 dihydrochloride, >=98% (HPLC) |
A888815 |
SR-00000001060 |
J-005723 |
SR-00000001060-1 |
Q27287129 |
Y-27632 - CAS 146986-50-7 |
(r)-(+)-trans-N-(4-pyridyl)-4-(1-aminoethyl)-cyclohexanecarboxamide dihydrochloride |
(R)-4-(1-Aminoethyl)-N-(pyridin-4-yl)cyclohexane-1-carboxamide dihydrochloride |
4-(1R)-1-aminoethyl-N-pyridin-4-ylcyclohexane-1-carboxamide dihydrochloride |
trans-4-(R)-1-Aminoethyl-N-(4-pyridyl)cyclohexanecarboxamide dihydrochloride |
(1R,4R)-4-(1R)-1-AMINOETHYL-N-(PYRIDIN-4-YL)CYCLOHEXANE-1-CARBOXAMIDE DIHYDROCHLORIDE |
1983329-96-9 |
Trans-4-(1R)-1-Aminoethyl-N-4-pyridinylcyclohexanecarboxamide dihydrochloride (Y-27632 dihydrochloride) |
Experimental Data
Y-27632 dihydrochloride
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | 8.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Y-27632 dihydrochloride
Statistics Data
Y-27632 dihydrochloride
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 8.000000000000000 | 1 | 1 |
Statistics Data Visualization
Y-27632 dihydrochloride
