Compound Summary
Urapidil hydrochloride
Compound Information
Urapidil hydrochloride
Compound Name: | Urapidil hydrochloride |
Compound CID: | 167980 |
Synonyms: | Urapidil hydrochloride Urapidil HCl 64887-14-5 Urapidil (hydrochloride) UNII-PVU92PZO12 More... |
Iupac Name: | 6-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propylamino]-1,3-dimethylpyrimidine-2,4-dione;hydrochloride |
InChI: | InChI=1S/C20H29N5O3.ClH/c1-22-18(15-19(26)23(2)20(22)27)21-9-6-10-24-11-13-25(14-12-24)16-7-4-5-8-17(16)28-3;/h4-5,7-8,15,21H,6,9-14H2,1-3H3;1H |
InChIKey: | KTMLZVUAXJERAT-UHFFFAOYSA-N |
Canonical Smiles: | CN1C(=CC(=O)N(C1=O)C)NCCCN2CCN(CC2)C3=CC=CC=C3OC.Cl |
Isomeric Smiles: | CN1C(=CC(=O)N(C1=O)C)NCCCN2CCN(CC2)C3=CC=CC=C3OC.Cl |
Molecular Weight: | 423.9 |
Molecular Formula: | C20H30ClN5O3 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Urapidil hydrochloride
Molecular Weight: | 423.9 |
Molecular Formula: | C20H30ClN5O3 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 6 |
Rotatable Bond Count: | 7 |
Heavy Atom Count: | 29 |
Complexity: | 588 |
Synonyms
Urapidil hydrochloride
| Urapidil hydrochloride | Urapidil hydrochloride |
|---|---|
Urapidil hydrochloride |
Urapidil HCl |
64887-14-5 |
Urapidil (hydrochloride) |
UNII-PVU92PZO12 |
PVU92PZO12 |
NCGC00094502-01 |
Ebrantil (TN) |
DSSTox_CID_25812 |
DSSTox_RID_81149 |
DSSTox_GSID_45812 |
6-3-4-(2-methoxyphenyl)piperazin-1-ylpropylamino-1,3-dimethylpyrimidine-2,4-dione;hydrochloride |
6-((3-(4-(2-methoxyphenyl)piperazin-1-yl)propyl)amino)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione hydrochloride |
6-3-4-(2-methoxyphenyl)-1-piperazinylpropylamino-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione monohydrochloride |
SMR000058525 |
SR-01000075295 |
CAS-64887-14-5 |
Urapidil Hydrochloride,(S) |
Urapidil hydrochloride, solid |
C20H30ClN5O3 |
MLS000758309 |
MLS001424033 |
C20H29N5O3.HCl |
SCHEMBL1321654 |
CHEMBL1256716 |
DTXSID2045812 |
HY-B0354A |
HMS1570F12 |
Pharmakon1600-01503100 |
BCP23389 |
Tox21_111286 |
Tox21_501265 |
MFCD00078601 |
NSC758226 |
s2025 |
AKOS015994621 |
Tox21_111286_1 |
AC-8089 |
CCG-100798 |
H61U751 |
HS-0064 |
LP01265 |
NC00048 |
NSC-758226 |
NCGC00016066-14 |
NCGC00261950-01 |
EU-0101265 |
FT-0675734 |
SW197244-4 |
U-100 |
V0313 |
C76033 |
D08662 |
SR-01000075295-1 |
SR-01000075295-3 |
SR-01000075295-9 |
Q27286781 |
SR-01000075295-10 |
63-4-(o-Methoxyphenyl)-1-piperazinylpropylamino-1,3-dimethyluracil hydrochloride |
2,4(1H,3H)-Pyrimidinedione, 6-((3-(4-(2-methoxyphenyl)-1-piperazinyl)propyl)amino)-1,3-dimethyl-, monohydrochloride |
6-(3-(4-(2-methoxyphenyl)piperazin-1-yl)propylamino)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione hydrochloride |
6-3-4-(2-Methoxyphenyl)-1-pipera zinylpropylamino-1,3-dimethyl-2,4(1H,3H)-pyrimi dinedione hydrochloride |
6-3-4-(2-Methoxyphenyl)-1-piperazinylpropylamino-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione hydrochloride |
Experimental Data
Urapidil hydrochloride
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | 9.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Urapidil hydrochloride
Statistics Data
Urapidil hydrochloride
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 9.000000000000000 | 1 | 1 |
Statistics Data Visualization
Urapidil hydrochloride
