Compound Summary
Tyrphostin AG 879
Compound Information
Tyrphostin AG 879
Compound Name: | Tyrphostin AG 879 |
Compound CID: | 135419190 |
Synonyms: | Tyrphostin AG 879 148741-30-4 AG 879 AG-879 AG879 More... |
Iupac Name: | (E)-2-cyano-3-(3,5-ditert-butyl-4-hydroxyphenyl)prop-2-enethioamide |
InChI: | InChI=1S/C18H24N2OS/c1-17(2,3)13-8-11(7-12(10-19)16(20)22)9-14(15(13)21)18(4,5)6/h7-9,21H,1-6H3,(H2,20,22)/b12-7+ |
InChIKey: | XRZYELWZLNAXGE-KPKJPENVSA-N |
Canonical Smiles: | CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)C=C(C#N)C(=S)N |
Isomeric Smiles: | CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)/C=C(\C#N)/C(=S)N |
Molecular Weight: | 316.5 |
Molecular Formula: | C18H24N2OS |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Tyrphostin AG 879
Molecular Weight: | 316.5 |
Molecular Formula: | C18H24N2OS |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 22 |
Complexity: | 477 |
Synonyms
Tyrphostin AG 879
| Tyrphostin AG 879 | Tyrphostin AG 879 |
|---|---|
Tyrphostin AG 879 |
148741-30-4 |
AG 879 |
AG-879 |
AG879 |
Tyrphostin Ag-879 |
alpha-Cyano-(3,5-di-t-butyl-4-hydroxy)thiocinnamide |
(2E)-2-cyano-3-(3,5-di-tert-butyl-4-hydroxyphenyl)prop-2-enethioamide |
(E)-2-cyano-3-(3,5-di-tert-butyl-4-hydroxyphenyl)prop-2-enethioamide |
2-Propenethioamide, 3-(3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl)-2-cyano-, (E)- |
C18H24N2OS |
2-CYANO-3-(3,5-DI-TERT-BUTYL-4-HYDROXYPHENYL)PROP-2-ENETHIOAMIDE |
tyrphostin AG879 |
tyrphostin-AG-879 |
BiomolKI_000028 |
Lopac-T-2067 |
BiomolKI2_000036 |
Lopac0_001175 |
BMK1-D4 |
BSPBio_001398 |
SCHEMBL607701 |
SCHEMBL607703 |
CHEMBL539947 |
GTPL4863 |
SCHEMBL3731617 |
BCBcMAP01_000075 |
CHEBI:93041 |
DTXSID801017139 |
HMS1361F20 |
HMS1791F20 |
HMS1989F20 |
HMS3263L11 |
HMS3402F20 |
BCP08354 |
CS-D0050 |
EX-A1893 |
Tyrphostin AG 879 (AG 879) |
ZINC3871425 |
Tox21_501175 |
2775AH |
BDBM50468261 |
EI-258 |
MFCD00236450 |
s2816 |
AKOS024256594 |
CCG-100632 |
LP01175 |
SDCCGSBI-0051142.P002 |
SU-0879 |
Tyrphostin AG 879, 99% (HPLC) |
2-Propenethioamide,3-3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl-2-cyano-, (2E)- |
IDI1_033868 |
NCGC00016007-01 |
NCGC00016007-02 |
NCGC00016007-03 |
NCGC00016007-04 |
NCGC00016007-05 |
NCGC00016007-06 |
NCGC00016007-07 |
NCGC00016007-12 |
NCGC00094432-01 |
NCGC00094432-02 |
NCGC00094432-03 |
NCGC00094432-04 |
NCGC00094432-05 |
NCGC00261860-01 |
AC-33024 |
AS-73877 |
HY-20878 |
B1544 |
EU-0101175 |
SW219152-1 |
T 2067 |
SR-01000076151 |
A1-01966 |
SR-01000076151-1 |
AG 879 - CAS 148741-30-4 |
BRD-K59469039-001-03-1 |
BRD-K59469039-001-04-9 |
Q27074342 |
(E)-2-cyano-3-(3,5-ditert-butyl-4-hydroxyphenyl)prop-2-enethioamide |
(2E)-3-3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl-2-cyano-2-propenethioamide |
2-Propenethioamide, 3-3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl-2-cyano-, (2E)- |
AG-879|||(E)-3-Amino-2-(3,5-ditert-butyl-4-oxocyclohexa-2,5-dien-1-ylidene)methyl-3-sulfanylprop-2-enenitrile |
Experimental Data
Tyrphostin AG 879
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -92.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Tyrphostin AG 879
Statistics Data
Tyrphostin AG 879
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -92.000000000000000 | 1 | 1 |
Statistics Data Visualization
Tyrphostin AG 879
