Compound Summary
Tyrphostin AG 538
Compound Information
Tyrphostin AG 538
Compound Name: | Tyrphostin AG 538 |
Compound CID: | 5328760 |
Synonyms: | Tyrphostin AG 538 AG-538 AG 538 133550-18-2 (E)-2-(3,4-dihydroxybenzoyl)-3-(3,4-dihydroxyphenyl)prop-2-enenitrile More... |
Iupac Name: | (E)-2-(3,4-dihydroxybenzoyl)-3-(3,4-dihydroxyphenyl)prop-2-enenitrile |
InChI: | InChI=1S/C16H11NO5/c17-8-11(5-9-1-3-12(18)14(20)6-9)16(22)10-2-4-13(19)15(21)7-10/h1-7,18-21H/b11-5+ |
InChIKey: | CANOJKGQDCJDOX-VZUCSPMQSA-N |
Canonical Smiles: | C1=CC(=C(C=C1C=C(C#N)C(=O)C2=CC(=C(C=C2)O)O)O)O |
Isomeric Smiles: | C1=CC(=C(C=C1/C=C(\C#N)/C(=O)C2=CC(=C(C=C2)O)O)O)O |
Molecular Weight: | 297.26 |
Molecular Formula: | C16H11NO5 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Tyrphostin AG 538
Molecular Weight: | 297.26 |
Molecular Formula: | C16H11NO5 |
Hydrogen Bond Donor Count: | 4 |
Hydrogen Bond Acceptor Count: | 6 |
Rotatable Bond Count: | 3 |
Heavy Atom Count: | 22 |
Complexity: | 494 |
Synonyms
Tyrphostin AG 538
| Tyrphostin AG 538 | Tyrphostin AG 538 |
|---|---|
Tyrphostin AG 538 |
AG-538 |
AG 538 |
133550-18-2 |
(E)-2-(3,4-dihydroxybenzoyl)-3-(3,4-dihydroxyphenyl)prop-2-enenitrile |
NSC676485 |
Tyrphostin deriv. 24 |
Lopac-T-7822 |
ag538 |
Lopac0_001261 |
MLS002153408 |
CHEMBL56393 |
BDBM4293 |
SCHEMBL2678764 |
SCHEMBL2678765 |
REGID_for_CID_660907 |
CHEBI:92138 |
cid_5328760 |
REGID_for_CID_5328760 |
DTXSID701017643 |
HMS2233K10 |
HMS3263N04 |
ZINC3871438 |
Tox21_501261 |
HSCI1_000189 |
CCG-205335 |
LP01261 |
NSC-676485 |
SDCCGSBI-0051228.P002 |
alpha-Cyano-(3,4-dihydroxy)cinnamoyl-(3′,4′-dihydroxyphenyl)ketone |
NCGC00016054-01 |
NCGC00016054-02 |
NCGC00016054-03 |
NCGC00016054-04 |
NCGC00016054-05 |
NCGC00094499-01 |
NCGC00094499-02 |
NCGC00261946-01 |
SMR001230786 |
EU-0101261 |
T 7822 |
SR-01000076178 |
J-006400 |
SR-01000076178-1 |
AG 538 - CAS 133550-18-2 |
BRD-K07888196-001-01-8 |
(2E)-2-(3,4-Dihydroxybenzoyl)-3-(3,4-dihydroxyphenyl)-2-propenenitrile |
3-(3,4-Dihydroxyphenyl)-2-1-(3,4-dihydroxyphenyl)methanoylacrylonitrile |
(2E)-3-(3,4-dihydroxyphenyl)-2-(3,4-dihydroxyphenyl)carbonylprop-2-enenitrile |
(alphaE)-alpha-(3,4-Dihydroxyphenyl)methylene-3,4-dihydroxy-beta-oxo-benzenepropanenitrile |
3,4-Dihydroxy-a-(3,4-dihydroxybenzoyl)-cis-cinnamonitrile 2-Cyano-3 ,4 -dihydroxyacetophenone |
Experimental Data
Tyrphostin AG 538
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | 9.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Tyrphostin AG 538
Statistics Data
Tyrphostin AG 538
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 9.000000000000000 | 1 | 1 |
Statistics Data Visualization
Tyrphostin AG 538
