Compound Summary
Tyrphostin AG 34
Compound Information
Tyrphostin AG 34
Compound Name: | Tyrphostin AG 34 |
Compound CID: | 667645 |
Synonyms: | Tyrphostin AG 34 2-(3,4-dihydroxy-5-methoxyphenyl)methylidenepropanedinitrile 2-(3,4-dihydroxy-5-methoxyphenyl)methylenemalononitrile 2-(3,4-Dihydroxy-5-methoxybenzylidene)malononitrile AG-34 More... |
Iupac Name: | 2-[(3,4-dihydroxy-5-methoxyphenyl)methylidene]propanedinitrile |
InChI: | InChI=1S/C11H8N2O3/c1-16-10-4-7(2-8(5-12)6-13)3-9(14)11(10)15/h2-4,14-15H,1H3 |
InChIKey: | DWZFIFZYMHNRRV-UHFFFAOYSA-N |
Canonical Smiles: | COC1=CC(=CC(=C1O)O)C=C(C#N)C#N |
Isomeric Smiles: | COC1=CC(=CC(=C1O)O)C=C(C#N)C#N |
Molecular Weight: | 216.19 |
Molecular Formula: | C11H8N2O3 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Tyrphostin AG 34
Molecular Weight: | 216.19 |
Molecular Formula: | C11H8N2O3 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 16 |
Complexity: | 355 |
Synonyms
Tyrphostin AG 34
| Tyrphostin AG 34 | Tyrphostin AG 34 |
|---|---|
Tyrphostin AG 34 |
2-(3,4-dihydroxy-5-methoxyphenyl)methylidenepropanedinitrile |
2-(3,4-dihydroxy-5-methoxyphenyl)methylenemalononitrile |
2-(3,4-Dihydroxy-5-methoxybenzylidene)malononitrile |
AG-34 |
118409-54-4 |
Tyrphostin A24 |
Lopac-T-6318 |
Lopac0_001169 |
Oprea1_550548 |
CHEMBL80155 |
BDBM4340 |
SCHEMBL3459584 |
ZINC15332 |
MCK103237 |
MFCD00814022 |
AKOS024319659 |
CCG-205243 |
MCULE-6367545167 |
NCGC00016036-01 |
NCGC00016036-02 |
NCGC00016036-03 |
NCGC00094427-01 |
NCGC00094427-02 |
benzylidenemalononitrile (BMN) deriv. 24 |
EU-0101169 |
T 6318 |
(3,4-Dihydroxy-5-methoxybenzylidene)malononitrile |
SR-01000076166 |
SR-01000076166-1 |
Experimental Data
Tyrphostin AG 34
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | 8.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Tyrphostin AG 34
Statistics Data
Tyrphostin AG 34
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 8.000000000000000 | 1 | 1 |
Statistics Data Visualization
Tyrphostin AG 34
